| Aromatase inhibitors in the treatment of breast cancer RW Brueggemeier, JC Hackett, ES Diaz-Cruz Endocrine reviews 26 (3), 331-345, 2005 | 581 | 2005 |
| Early events in the photochemistry of aryl azides from femtosecond UV/Vis spectroscopy and quantum chemical calculations G Burdzinski, JC Hackett, J Wang, TL Gustafson, CM Hadad, MS Platz Journal of the American Chemical Society 128 (41), 13402-13411, 2006 | 167 | 2006 |
| Synthesis and aromatase inhibitory activity of novel pyridine-containing isoflavones YW Kim, JC Hackett, RW Brueggemeier Journal of medicinal chemistry 47 (16), 4032-4040, 2004 | 124 | 2004 |
| The final catalytic step of cytochrome P450 aromatase: a density functional theory study JC Hackett, RW Brueggemeier, CM Hadad Journal of the American Chemical Society 127 (14), 5224-5237, 2005 | 121 | 2005 |
| Photoswitchable anticancer activity via trans–cis isomerization of a combretastatin A-4 analog JE Sheldon, MM Dcona, CE Lyons, JC Hackett, MCT Hartman Organic & biomolecular chemistry 14 (1), 40-49, 2016 | 98 | 2016 |
| Peroxo− iron mediated deformylation in sterol 14α-demethylase catalysis K Sen, JC Hackett Journal of the American Chemical Society 132 (30), 10293-10305, 2010 | 80 | 2010 |
| Evidence for an elevated aspartate pKa in the active site of human aromatase G Di Nardo, M Breitner, A Bandino, D Ghosh, GK Jennings, JC Hackett, ... Journal of Biological Chemistry 290 (2), 1186-1196, 2015 | 57 | 2015 |
| Competition between α-Cleavage and Energy Transfer in α-Azidoacetophenones S Muthukrishnan, SM Mandel, JC Hackett, PND Singh, CM Hadad, ... The Journal of Organic Chemistry 72 (8), 2757-2768, 2007 | 56 | 2007 |
| Tetrahydrofolate recognition by the mitochondrial folate transporter SA Lawrence, JC Hackett, RG Moran Journal of Biological Chemistry 286 (36), 31480-31489, 2011 | 54 | 2011 |
| Synthesis and characterization of azole isoflavone inhibitors of aromatase JC Hackett, YW Kim, B Su, RW Brueggemeier Bioorganic & medicinal chemistry 13 (12), 4063-4070, 2005 | 53 | 2005 |
| The Direct Detection of an Aryl Azide Excited State: An Ultrafast Study of the Photochemistry of para- and ortho-Biphenyl Azide GT Burdzinski, TL Gustafson, JC Hackett, CM Hadad, MS Platz Journal of the American Chemical Society 127 (40), 13764-13765, 2005 | 52 | 2005 |
| Acid/base and hydrogen bonding effects on the proton-coupled electron transfer of quinones and hydroquinones in acetonitrile: Mechanistic investigation by voltammetry, 1H NMR … TM Alligrant, JC Hackett, JC Alvarez Electrochimica acta 55 (22), 6507-6516, 2010 | 51 | 2010 |
| Coupled electron transfer and proton hopping in the final step of CYP19-catalyzed androgen aromatization K Sen, JC Hackett Biochemistry 51 (14), 3039-3049, 2012 | 47 | 2012 |
| Metabolic approaches to treatment of melanoma P Hersey, RN Watts, XD Zhang, J Hackett Clinical Cancer Research 15 (21), 6490-6494, 2009 | 42 | 2009 |
| Oxidative dehalogenation of perhalogenated benzenes by cytochrome P450 compound I JC Hackett, TT Sanan, CM Hadad Biochemistry 46 (20), 5924-5940, 2007 | 42 | 2007 |
| Membrane-embedded substrate recognition by cytochrome P450 3A4 JC Hackett Journal of Biological Chemistry 293 (11), 4037-4046, 2018 | 40 | 2018 |
| Early events in the photochemistry of 2-naphthyl azide from femtosecond UV/Vis spectroscopy and quantum chemical calculations: Direct observation of a very short-lived singlet … J Wang, J Kubicki, G Burdzinski, JC Hackett, TL Gustafson, CM Hadad, ... The Journal of organic chemistry 72 (20), 7581-7586, 2007 | 40 | 2007 |
| Engineered P450 biocatalysts show improved activity and regio-promiscuity in aromatic nitration R Zuo, Y Zhang, C Jiang, JC Hackett, R Loria, SD Bruner, Y Ding Scientific reports 7 (1), 842, 2017 | 39 | 2017 |
| Molecular oxygen activation and proton transfer mechanisms in lanosterol 14α-demethylase catalysis K Sen, JC Hackett The Journal of Physical Chemistry B 113 (23), 8170-8182, 2009 | 35 | 2009 |
| Lead optimization of 7-benzyloxy 2-(4′-pyridylmethyl) thio isoflavone aromatase inhibitors B Su, JC Hackett, ES Díaz-Cruz, YW Kim, RW Brueggemeier Bioorganic & medicinal chemistry 13 (23), 6571-6577, 2005 | 32 | 2005 |
Christopher M HadadOhio State UniversityAdresse e-mail validée de osu.edu
