Single-cell transcriptomics of the human retinal pigment epithelium and choroid in health and macular degeneration AP Voigt, K Mulfaul, NK Mullin, MJ Flamme-Wiese, JC Giacalone, ... Proceedings of the National Academy of Sciences 116 (48), 24100-24107, 2019 | 246 | 2019 |
IL-18 attenuates experimental choroidal neovascularization as a potential therapy for wet age-related macular degeneration SL Doyle, E Ozaki, K Brennan, MM Humphries, K Mulfaul, J Keaney, ... Science translational medicine 6 (230), 230ra44-230ra44, 2014 | 120 | 2014 |
Plasmonics-enhanced and optically modulated delivery of gold nanostars into brain tumor H Yuan, CM Wilson, J Xia, SL Doyle, S Li, AM Fales, Y Liu, E Ozaki, ... Nanoscale 6 (8), 4078-4082, 2014 | 62 | 2014 |
Interleukin-36 cytokines alter the intestinal microbiome and can protect against obesity and metabolic dysfunction E Giannoudaki, YE Hernandez-Santana, K Mulfaul, SL Doyle, E Hams, ... Nature communications 10 (1), 4003, 2019 | 56 | 2019 |
IL-18 immunotherapy for neovascular AMD: tolerability and efficacy in nonhuman primates SL Doyle, FJ López, L Celkova, K Brennan, K Mulfaul, E Ozaki, PF Kenna, ... Investigative ophthalmology & visual science 56 (9), 5424-5430, 2015 | 47 | 2015 |
Toll-like receptor 2 facilitates oxidative damage-induced retinal degeneration K Mulfaul, E Ozaki, N Fernando, K Brennan, KR Chirco, E Connolly, ... Cell reports 30 (7), 2209-2224. e5, 2020 | 46 | 2020 |
Bulk and single-cell gene expression analyses reveal aging human choriocapillaris has pro-inflammatory phenotype AP Voigt, SS Whitmore, K Mulfaul, KR Chirco, JC Giacalone, ... Microvascular research 131, 104031, 2020 | 33 | 2020 |
Choroidal endothelial and macrophage gene expression in atrophic and neovascular macular degeneration AP Voigt, NK Mullin, K Mulfaul, LP Lozano, LA Wiley, MJ Flamme-Wiese, ... Human molecular genetics 31 (14), 2406-2423, 2022 | 27 | 2022 |
Toll-like receptors and age-related macular degeneration K Mulfaul, M Rhatigan, S Doyle Retinal Degenerative Diseases: Mechanisms and Experimental Therapy, 19-28, 2018 | 21 | 2018 |
Stepwise differentiation and functional characterization of human induced pluripotent stem cell-derived choroidal endothelial cells K Mulfaul, JC Giacalone, AP Voigt, MJ Riker, D Ochoa, IC Han, EM Stone, ... Stem cell research & therapy 11, 1-10, 2020 | 17 | 2020 |
Local factor H production by human choroidal endothelial cells mitigates complement deposition: implications for macular degeneration K Mulfaul, NK Mullin, JC Giacalone, AP Voigt, M R DeVore, EM Stone, ... The Journal of pathology 257 (1), 29-38, 2022 | 13 | 2022 |
Type 1 IFN induction by cytosolic nucleic acid is intact in neonatal mononuclear cells, contrasting starkly with neonatal hyporesponsiveness to TLR ligation due to independence … K Brennan, BD O’Leary, D Mc Laughlin, EP Breen, E Connolly, N Ali, ... The Journal of Immunology 201 (4), 1131-1143, 2018 | 13 | 2018 |
The essential role of the choriocapillaris in vision: novel insights from imaging and molecular biology K Mulfaul, JF Russell, AP Voigt, EM Stone, BA Tucker, RF Mullins Annual review of vision science 8, 33-52, 2022 | 7 | 2022 |
TLR2 bridges oxidative damage and complement-associated pathology and is a therapeutic target for age-related macular degeneration. S Doyle, K Mulfaul, N Fernando, K Chirco, E Connolly, T Ryan, E Ozaki, ... Investigative Ophthalmology & Visual Science 59 (9), 3475-3475, 2018 | 2 | 2018 |
Development of chemically crosslinked PEG-PAA hydrogels suitable for engineering of the vascularized outer retina N Pandala, M LaScola, K Mulfaul, EM Stone, RF Mullins, BA Tucker, ... Investigative Ophthalmology & Visual Science 63 (7), 3735–F0341-3735–F0341, 2022 | 1 | 2022 |
Inflammatory cytokine profiling identifies elevated G-CSF protein in human age-related macular degeneration (AMD) donor choroid. K Mulfaul, X Liu, MJ Riker, EM Stone, BA Tucker, R Mullins Investigative Ophthalmology & Visual Science 64 (8), 5388-5388, 2023 | | 2023 |
Method of treating age-related macular degeneration S Doyle, M Campbell, E Ozaki, K Mulfaul US Patent App. 17/671,688, 2022 | | 2022 |
A novel perfusion system for modeling the outer retina-RPE-choriocapillaris unit in vitro NE Stone, A Shrestha, K Mulfaul, RF Mullins, BA Tucker Investigative Ophthalmology & Visual Science 63 (7), 3156–F0430-3156–F0430, 2022 | | 2022 |
Relative abundance of FH and FHR-4 in genotyped human donor eyes: significance for AMD pathogenesis K Mulfaul, MM Collins, LM Affatigato, EM Stone, BA Tucker, RF Mullins Investigative Ophthalmology & Visual Science 63 (7), 4615–F0407-4615–F0407, 2022 | | 2022 |
Local CFH synthesis protects choroidal endothelial cells from membrane attack complex formation. K Mulfaul, NK Mullin, JC Giacalone, A Shrestha, HT Daggett, EM Stone, ... Investigative Ophthalmology & Visual Science 62 (8), 2927-2927, 2021 | | 2021 |