| The emerging mechanisms of isoform-specific PI3K signalling B Vanhaesebroeck, J Guillermet-Guibert, M Graupera, B Bilanges Nature reviews Molecular cell biology 11 (5), 329-341, 2010 | 1981 | 2010 |
| Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration M Graupera, J Guillermet-Guibert, LC Foukas, LK Phng, RJ Cain, ... Nature 453 (7195), 662-666, 2008 | 597 | 2008 |
| Simvastatin treatment improves liver sinusoidal endothelial dysfunction in CCl4 cirrhotic rats JG Abraldes, A Rodríguez-Vilarrupla, M Graupera, C Zafra, ... Journal of hepatology 46 (6), 1040-1046, 2007 | 275 | 2007 |
| cKit lineage hemogenic endothelium-derived cells contribute to mesenteric lymphatic vessels L Stanczuk, I Martinez-Corral, MH Ulvmar, Y Zhang, B Laviña, M Fruttiger, ... Cell reports 10 (10), 1708-1721, 2015 | 245 | 2015 |
| Targeting PI3K in cancer: impact on tumor cells, their protective stroma, angiogenesis, and immunotherapy K Okkenhaug, M Graupera, B Vanhaesebroeck Cancer discovery 6 (10), 1090-1105, 2016 | 234 | 2016 |
| The metabolic co-regulator PGC1α suppresses prostate cancer metastasis V Torrano, L Valcarcel-Jimenez, AR Cortazar, X Liu, J Urosevic, ... Nature cell biology 18 (6), 645-656, 2016 | 203 | 2016 |
| Cyclooxygenase-derived products modulate the increased intrahepatic resistance of cirrhotic rat livers M Graupera, JC Garcıa-Pagán, JG Abraldes, C Peralta, M Bragulat, ... Hepatology 37 (1), 172-181, 2003 | 202 | 2003 |
| Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans SD Castillo, E Tzouanacou, M Zaw-Thin, IM Berenjeno, VER Parker, ... Science translational medicine 8 (332), 332ra43-332ra43, 2016 | 170 | 2016 |
| Re-education of tumor-associated macrophages by CXCR2 blockade drives senescence and tumor inhibition in advanced prostate cancer D Di Mitri, M Mirenda, J Vasilevska, A Calcinotto, N Delaleu, A Revandkar, ... Cell reports 28 (8), 2156-2168. e5, 2019 | 155 | 2019 |
| PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia R Ola, A Dubrac, J Han, F Zhang, JS Fang, B Larrivée, M Lee, AA Urarte, ... Nature communications 7 (1), 13650, 2016 | 154 | 2016 |
| Integrin-dependent and-independent functions of astrocytic fibronectin in retinal angiogenesis D Stenzel, A Lundkvist, D Sauvaget, M Busse, M Graupera, ... Development 138 (20), 4451-4463, 2011 | 150 | 2011 |
| 5-Lipoxygenase inhibition reduces intrahepatic vascular resistance of cirrhotic rat livers: a possible role of cysteinyl-leukotrienes M Graupera, JC García–Pagán, E Titos, J Claria, A Massaguer, J Bosch, ... Gastroenterology 122 (2), 387-393, 2002 | 136 | 2002 |
| Regulation of angiogenesis by PI3K signaling networks M Graupera, M Potente Experimental cell research 319 (9), 1348-1355, 2013 | 133 | 2013 |
| Resistance to antiangiogenic therapies by metabolic symbiosis in renal cell carcinoma PDX models and patients G Jiménez-Valerio, M Martínez-Lozano, N Bassani, A Vidal, ... Cell reports 15 (6), 1134-1143, 2016 | 114 | 2016 |
| Developmental and tumor angiogenesis requires the mitochondria-shaping protein Opa1 S Herkenne, O Ek, M Zamberlan, A Pellattiero, M Chergova, I Chivite, ... Cell metabolism 31 (5), 987-1003. e8, 2020 | 109 | 2020 |
| PTEN mediates Notch-dependent stalk cell arrest in angiogenesis H Serra, I Chivite, A Angulo-Urarte, A Soler, JD Sutherland, ... Nature communications 6 (1), 7935, 2015 | 109 | 2015 |
| Cyclooxygenase-1 inhibition corrects endothelial dysfunction in cirrhotic rat livers M Graupera, JC Garcı́a-Pagán, M Parés, JG Abraldes, J Roselló, J Bosch, ... Journal of hepatology 39 (4), 515-521, 2003 | 102 | 2003 |
| Sinusoidal endothelial COX-1-derived prostanoids modulate the hepatic vascular tone of cirrhotic rat livers M Graupera, S March, P Engel, J Rodés, J Bosch, JC Garcia-Pagan American Journal of Physiology-Gastrointestinal and Liver Physiology 288 (4 …, 2005 | 96 | 2005 |
| Resistance to targeted therapies in renal cancer: the importance of changing the mechanism of action I Duran, J Lambea, P Maroto, JL González-Larriba, L Flores, ... Targeted oncology 12, 19-35, 2017 | 94 | 2017 |
| Metronomic chemotherapy following the maximum tolerated dose is an effective anti‐tumour therapy affecting angiogenesis, tumour dissemination and cancer stem cells M Vives, MM Ginestà, K Gracova, M Graupera, O Casanovas, G Capella, ... International journal of cancer 133 (10), 2464-2472, 2013 | 94 | 2013 |
