Suivre
Kevin Wei
Kevin Wei
Assistant Professor of Medicine, Harvard Medical School, Brigham and Women's Hospital
Adresse e-mail validée de bwh.harvard.edu
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Année
Fast, sensitive and accurate integration of single-cell data with Harmony
I Korsunsky, N Millard, J Fan, K Slowikowski, F Zhang, K Wei, ...
Nature methods 16 (12), 1289-1296, 2019
38292019
A novel chemokine receptor for SDF-1 and I-TAC involved in cell survival, cell adhesion, and tumor development
JM Burns, BC Summers, Y Wang, A Melikian, R Berahovich, Z Miao, ...
The Journal of experimental medicine 203 (9), 2201-2213, 2006
16182006
Pathologically expanded peripheral T helper cell subset drives B cells in rheumatoid arthritis
DA Rao, MF Gurish, JL Marshall, K Slowikowski, CY Fonseka, Y Liu, ...
Nature 542 (7639), 110-114, 2017
8852017
Defining inflammatory cell states in rheumatoid arthritis joint synovial tissues by integrating single-cell transcriptomics and mass cytometry
F Zhang, K Wei, K Slowikowski, CY Fonseka, DA Rao, S Kelly, ...
Nature immunology 20 (7), 928-942, 2019
8632019
Distinct fibroblast subsets drive inflammation and damage in arthritis
AP Croft, J Campos, K Jansen, JD Turner, J Marshall, M Attar, L Savary, ...
Nature 570 (7760), 246-251, 2019
6502019
Metabolic reprogramming of natural killer cells in obesity limits antitumor responses
X Michelet, L Dyck, A Hogan, RM Loftus, D Duquette, K Wei, S Beyaz, ...
Nature immunology 19 (12), 1330-1340, 2018
4822018
Functionally distinct disease-associated fibroblast subsets in rheumatoid arthritis
F Mizoguchi, K Slowikowski, K Wei, JL Marshall, DA Rao, SK Chang, ...
Nature communications 9 (1), 789, 2018
4272018
Notch signalling drives synovial fibroblast identity and arthritis pathology
K Wei, I Korsunsky, JL Marshall, A Gao, GFM Watts, T Major, AP Croft, ...
Nature 582 (7811), 259-264, 2020
3052020
AXL is an essential factor and therapeutic target for metastatic ovarian cancer
EB Rankin, KC Fuh, TE Taylor, AJ Krieg, M Musser, J Yuan, K Wei, ...
Cancer research 70 (19), 7570-7579, 2010
2432010
VEGF modulates erythropoiesis through regulation of adult hepatic erythropoietin synthesis
BYY Tam, K Wei, JS Rudge, J Hoffman, J Holash, S Park, J Yuan, ...
Nature medicine 12 (7), 793-800, 2006
1782006
HBEGF+ macrophages in rheumatoid arthritis induce fibroblast invasiveness
D Kuo, J Ding, IS Cohn, F Zhang, K Wei, DA Rao, C Rozo, UK Sokhi, ...
Science translational medicine 11 (491), eaau8587, 2019
1602019
Cross-talk between hypoxia and insulin signaling through Phd3 regulates hepatic glucose and lipid metabolism and ameliorates diabetes
CM Taniguchi, EC Finger, AJ Krieg, C Wu, AN Diep, EL LaGory, K Wei, ...
Nature medicine 19 (10), 1325-1330, 2013
1572013
Autocrine loop involving IL-6 family member LIF, LIF receptor, and STAT4 drives sustained fibroblast production of inflammatory mediators
HN Nguyen, EH Noss, F Mizoguchi, C Huppertz, KS Wei, GFM Watts, ...
Immunity 46 (2), 220-232, 2017
1422017
IL-1-driven stromal–neutrophil interactions define a subset of patients with inflammatory bowel disease that does not respond to therapies
M Friedrich, M Pohin, MA Jackson, I Korsunsky, SJ Bullers, ...
Nature Medicine 27 (11), 1970-1981, 2021
1362021
A liver Hif-2α–Irs2 pathway sensitizes hepatic insulin signaling and is modulated by Vegf inhibition
K Wei, SM Piecewicz, LM McGinnis, CM Taniguchi, SJ Wiegand, ...
Nature medicine 19 (10), 1331-1337, 2013
1142013
Methods for high-dimensional analysis of cells dissociated from cryopreserved synovial tissue
LT Donlin, DA Rao, K Wei, K Slowikowski, MJ McGeachy, JD Turner, ...
Arthritis research & therapy 20, 1-15, 2018
982018
Cross-tissue, single-cell stromal atlas identifies shared pathological fibroblast phenotypes in four chronic inflammatory diseases
I Korsunsky, K Wei, M Pohin, EY Kim, F Barone, T Major, E Taylor, ...
Med 3 (7), 481-518. e14, 2022
962022
Fibroblast pathology in inflammatory diseases
K Wei, HN Nguyen, MB Brenner
The Journal of clinical investigation 131 (20), 2021
962021
Accelerating Medicines Partnership Rheumatoid Arthritis and Systemic Lupus Erythematosus (AMP RA/SLE) Consortium
F Zhang, K Wei, K Slowikowski, CY Fonseka, DA Rao, S Kelly, ...
Defining inflammatory cell states in rheumatoid arthritis joint synovial …, 2019
872019
Granzyme K+ CD8 T cells form a core population in inflamed human tissue
AH Jonsson, F Zhang, G Dunlap, E Gomez-Rivas, GFM Watts, HJ Faust, ...
Science translational medicine 14 (649), eabo0686, 2022
832022
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