Sébastien Viel
Sébastien Viel
University of Lyon
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Autoantibodies against type I IFNs in patients with life-threatening COVID-19
P Bastard, LB Rosen, Q Zhang, E Michailidis, HH Hoffmann, Y Zhang, ...
Science 370 (6515), eabd4585, 2020
Inborn errors of type I IFN immunity in patients with life-threatening COVID-19
Q Zhang, P Bastard, Z Liu, J Le Pen, M Moncada-Velez, J Chen, M Ogishi, ...
Science 370 (6515), eabd4570, 2020
Should we stimulate or suppress immune responses in COVID-19? Cytokine and anti-cytokine interventions
Y Jamilloux, T Henry, A Belot, S Viel, M Fauter, T El Jammal, T Walzer, ...
Autoimmunity reviews 19 (7), 102567, 2020
TGF-β inhibits the activation and functions of NK cells by repressing the mTOR pathway
S Viel, A Marçais, FSF Guimaraes, R Loftus, J Rabilloud, M Grau, ...
Science signaling 9 (415), ra19-ra19, 2016
The metabolic checkpoint kinase mTOR is essential for IL-15 signaling during the development and activation of NK cells
A Marçais, J Cherfils-Vicini, C Viant, S Degouve, S Viel, A Fenis, ...
Nature immunology 15 (8), 749-757, 2014
T-bet and Eomes instruct the development of two distinct natural killer cell lineages in the liver and in the bone marrow
C Daussy, F Faure, K Mayol, S Viel, G Gasteiger, E Charrier, J Bienvenu, ...
Journal of Experimental Medicine 211 (3), 563-577, 2014
Autoantibodies neutralizing type I IFNs are present in~ 4% of uninfected individuals over 70 years old and account for~ 20% of COVID-19 deaths
P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, J Manry, ...
Science immunology 6 (62), eabl4340, 2021
X-linked recessive TLR7 deficiency in~ 1% of men under 60 years old with life-threatening COVID-19
T Asano, B Boisson, F Onodi, D Matuozzo, M Moncada-Velez, ...
Science immunology 6 (62), eabl4348, 2021
In vitro tests for drug hypersensitivity reactions: an ENDA/EAACI Drug Allergy Interest Group position paper
C Mayorga, G Celik, P Rouzaire, P Whitaker, P Bonadonna, ...
Allergy 71 (8), 1103-1134, 2016
Type I IFN immunoprofiling in COVID-19 patients
S Trouillet-Assant, S Viel, A Gaymard, S Pons, JC Richard, M Perret, ...
Journal of Allergy and Clinical Immunology 146 (1), 206-208. e2, 2020
Regulation of mouse NK cell development and function by cytokines
A Marçais, S Viel, M Grau, T Henry, J Marvel, T Walzer
Frontiers in immunology 4, 450, 2013
Terminal NK cell maturation is controlled by concerted actions of T-bet and Zeb2 and is essential for melanoma rejection
MJ Van Helden, S Goossens, C Daussy, AL Mathieu, F Faure, A Marcais, ...
Journal of experimental medicine 212 (12), 2015-2025, 2015
T‐bet and Eomes govern differentiation and function of mouse and human NK cells and ILC1
J Zhang, M Marotel, S Fauteux‐Daniel, AL Mathieu, S Viel, A Marçais, ...
European journal of immunology 48 (5), 738-750, 2018
The risk of COVID-19 death is much greater and age dependent with type I IFN autoantibodies
J Manry, P Bastard, A Gervais, T Le Voyer, J Rosain, Q Philippot, ...
Proceedings of the National Academy of Sciences 119 (21), 2022
Commercial anti‐CD19 CAR T cell therapy for patients with relapsed/refractory aggressive B cell lymphoma in a European center
P Sesques, E Ferrant, V Safar, F Wallet, J Tordo, A Dhomps, L Karlin, ...
American journal of hematology 95 (11), 1324-1333, 2020
Alteration of natural killer cell phenotype and function in obese individuals
S Viel, L Besson, E Charrier, A Marçais, E Disse, J Bienvenu, T Walzer, ...
Clinical immunology 177, 12-17, 2017
PRKDC mutations associated with immunodeficiency, granuloma, and autoimmune regulator–dependent autoimmunity
AL Mathieu, E Verronese, GI Rice, F Fouyssac, Y Bertrand, C Picard, ...
Journal of Allergy and Clinical Immunology 135 (6), 1578-1588. e5, 2015
Monogenic lupus: dissecting heterogeneity
O Omarjee, C Picard, C Frachette, M Moreews, F Rieux-Laucat, ...
Autoimmunity reviews 18 (10), 102361, 2019
Early-onset autoimmunity associated with SOCS1 haploinsufficiency
J Hadjadj, CN Castro, M Tusseau, MC Stolzenberg, F Mazerolles, ...
Nature communications 11 (1), 5341, 2020
High mTOR activity is a hallmark of reactive natural killer cells and amplifies early signaling through activating receptors
A Marçais, M Marotel, S Degouve, A Koenig, S Fauteux-Daniel, ...
Elife 6, e26423, 2017
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