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Patrick Kwok Shing Ng
Patrick Kwok Shing Ng
The Jackson Laboratory For Genomic Medicine
Verified email at jax.org
Title
Cited by
Cited by
Year
Comprehensive molecular profiling of lung adenocarcinoma
Cancer Genome Atlas Research Network
Nature 511 (7511), 543-550, 2014
38022014
Comprehensive genomic characterization of head and neck squamous cell carcinomas
Cancer Genome Atlas Network
Nature 517 (7536), 576-582, 2015
32052015
Comprehensive characterization of cancer driver genes and mutations
MH Bailey, C Tokheim, E Porta-Pardo, S Sengupta, D Bertrand, ...
Cell 173 (2), 371-385. e18, 2018
21342018
Frequent Mutation of the PI3K Pathway in Head and Neck Cancer Defines Predictive BiomarkersMutation of PI3K Pathway in Head and Neck Cancer
VWY Lui, ML Hedberg, H Li, BS Vangara, K Pendleton, Y Zeng, Y Lu, ...
Cancer discovery 3 (7), 761-769, 2013
6402013
A pan-cancer proteomic perspective on The Cancer Genome Atlas
R Akbani, PKS Ng, HMJ Werner, M Shahmoradgoli, F Zhang, Z Ju, W Liu, ...
Nature communications 5 (1), 1-15, 2014
5472014
A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations
Y Zhang, PKS Ng, M Kucherlapati, F Chen, Y Liu, YH Tsang, ...
Cancer Cell 31 (6), 820-832. e3, 2017
5112017
Comprehensive Molecular Characterization of the Hippo Signaling Pathway in Cancer
Y Wang, X Xu, D Maglic, MT Dill, K Mojumdar, PKS Ng, KJ Jeong, ...
Cell reports 25 (5), 1304-1317. e5, 2018
3542018
Systematic Functional Annotation of Somatic Mutations in Cancer
PKS Ng, J Li, KJ Jeong, S Shao, H Chen, YH Tsang, S Sengupta, Z Wang, ...
Cancer cell 33 (3), 450-462. e10, 2018
2432018
Rational combination therapy with PARP and MEK inhibitors capitalizes on therapeutic liabilities in RAS mutant cancers
C Sun, Y Fang, J Yin, J Chen, Z Ju, D Zhang, X Chen, CP Vellano, ...
Science translational medicine 9 (392), 2017
1972017
The draft genome, transcriptome, and microbiome of Dermatophagoides farinae reveal a broad spectrum of dust mite allergens
TF Chan, KM Ji, AKY Yim, XY Liu, JW Zhou, RQ Li, KY Yang, J Li, M Li, ...
Journal of Allergy and Clinical Immunology 135 (2), 539-548, 2015
1942015
Cloning and expression analysis of two distinct HIF-alpha isoforms–gcHIF-1alpha and gcHIF-4alpha–from the hypoxia-tolerant grass carp, Ctenopharyngodon idellus
SHW Law, RSS Wu, PKS Ng, RMK Yu, RYC Kong
BMC molecular biology 7, 1-13, 2006
1572006
Frequent mutation of receptor protein tyrosine phosphatases provides a mechanism for STAT3 hyperactivation in head and neck cancer
VWY Lui, ND Peyser, PKS Ng, J Hritz, Y Zeng, Y Lu, H Li, L Wang, ...
Proceedings of the National Academy of Sciences 111 (3), 1114-1119, 2014
1152014
Naturally occurring neomorphic pik3r1 mutations activate the MAPK pathway, dictating therapeutic response to MAPK pathway inhibitors
LWT Cheung, S Yu, D Zhang, J Li, PKS Ng, N Panupinthu, S Mitra, Z Ju, ...
Cancer cell 26 (4), 479-494, 2014
892014
A Comprehensive Evaluation of Biomarkers Predictive of Response to PI3K Inhibitors and of Resistance Mechanisms in Head and Neck Squamous Cell CarcinomaPI3K Pathway Inhibition …
T Mazumdar, LA Byers, PKS Ng, GB Mills, S Peng, L Diao, YH Fan, ...
Molecular cancer therapeutics 13 (11), 2738-2750, 2014
852014
RET fusion as a novel driver of medullary thyroid carcinoma
EG Grubbs, PKS Ng, J Bui, NL Busaidy, K Chen, JE Lee, X Lu, H Lu, ...
The Journal of Clinical Endocrinology & Metabolism 100 (3), 788-793, 2015
812015
Hypoxia induces telomerase reverse transcriptase (TERT) gene expression in non-tumor fish tissues in vivo: the marine medaka (Oryzias melastigma) model
RMK Yu, EXH Chen, RYC Kong, PKS Ng, HOL Mok, DWT Au
BMC Molecular Biology 7, 1-12, 2006
692006
Inhibition of c-Met downregulates TIGAR expression and reduces NADPH production leading to cell death
VWY Lui, EYL Wong, K Ho, PKS Ng, CPY Lau, SKW Tsui, CM Tsang, ...
Oncogene 30 (9), 1127-1134, 2011
682011
Enhancement of hypoxia-induced gene expression in fish liver by the aryl hydrocarbon receptor (AhR) ligand, benzo [a] pyrene (BaP)
RMK Yu, PKS Ng, T Tan, DLH Chu, RSS Wu, RYC Kong
Aquatic toxicology 90 (3), 235-242, 2008
642008
Characterization of a hypoxia-responsive leptin receptor (omLepR L) cDNA from the marine medaka (Oryzias melastigma)
MML Wong, RMK Yu, PKS Ng, SHW Law, AKC Tsang, RYC Kong
Marine pollution bulletin 54 (6), 797-803, 2007
632007
Molecular landscape of BRAF-mutant NSCLC reveals an association between clonality and driver mutations and identifies targetable non-V600 driver mutations
MV Negrao, VM Raymond, RB Lanman, JP Robichaux, J He, MB Nilsson, ...
Journal of Thoracic Oncology 15 (10), 1611-1623, 2020
522020
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