Suivre
VIctoria H. Cowling
VIctoria H. Cowling
Professor of Cancer Biology, Beatson Institute, UK
Adresse e-mail validée de glasgow.ac.uk
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Année
Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain
V Cowling, J Downward
Cell Death & Differentiation 9 (10), 1046-1056, 2002
3422002
Regulation of mRNA cap methylation
VH Cowling
Biochemical Journal 425 (2), 295-302, 2010
2952010
Cap-binding complex (CBC)
T Gonatopoulos-Pournatzis, VH Cowling
Biochemical Journal 457 (2), 231-242, 2014
2282014
Mechanism of transcriptional activation by the Myc oncoproteins
VH Cowling, MD Cole
Seminars in cancer biology 16 (4), 242-252, 2006
2172006
Transcription-independent functions of MYC: regulation of translation and DNA replication
MD Cole, VH Cowling
Nature reviews Molecular cell biology 9 (10), 810-815, 2008
1972008
mRNA cap regulation in mammalian cell function and fate
A Galloway, VH Cowling
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1862 (3), 270-279, 2019
1932019
The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding
VH Cowling, MD Cole
Molecular and cellular biology 27 (6), 2059-2073, 2007
1922007
Single cell tuning of Myc expression by antigen receptor signal strength and interleukin‐2 in T lymphocytes
GC Preston, LV Sinclair, A Kaskar, JL Hukelmann, MN Navarro, I Ferrero, ...
The EMBO journal 34 (15), 2008-2024, 2015
1622015
A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response
S Chandriani, E Frengen, VH Cowling, SA Pendergrass, CM Perou, ...
PloS one 4 (8), e6693, 2009
1622009
Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi
LM Martins, BE Turk, V Cowling, A Borg, ET Jarrell, LC Cantley, ...
Journal of Biological Chemistry 278 (49), 49417-49427, 2003
1612003
Nestin is expressed in the basal/myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors
H Li, P Cherukuri, N Li, V Cowling, M Spinella, M Cole, AK Godwin, ...
Cancer research 67 (2), 501-510, 2007
1502007
Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells
B Nicke, J Bastien, SJ Khanna, PH Warne, V Cowling, SJ Cook, G Peters, ...
Molecular cell 20 (5), 673-685, 2005
1502005
A conserved Myc protein domain, MBIV, regulates DNA binding, apoptosis, transformation, and G2 arrest
VH Cowling, S Chandriani, ML Whitfield, MD Cole
Molecular and cellular biology, 2006
1432006
c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1
VH Cowling, CM D'Cruz, LA Chodosh, MD Cole
Molecular and cellular biology 27 (14), 5135-5146, 2007
1312007
SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation
D Varshney, J Vavrova-Anderson, AJ Oler, VH Cowling, BR Cairns, ...
Nature communications 6 (1), 6569, 2015
892015
RAM/Fam103a1 is required for mRNA cap methylation
T Gonatopoulos-Pournatzis, S Dunn, R Bounds, VH Cowling
Molecular cell 44 (4), 585-596, 2011
862011
Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors
MD Cole, VH Cowling
Oncogene 28 (9), 1169-1175, 2009
862009
E-cadherin repression contributes to c-Myc-induced epithelial cell transformation
VH Cowling, MD Cole
Oncogene 26 (24), 3582-3586, 2007
802007
Enhanced mRNA cap methylation increases cyclin D1 expression and promotes cell transformation
VH Cowling
Oncogene 29 (6), 930-936, 2010
752010
S-adenosyl homocysteine hydrolase is required for Myc-induced mRNA cap methylation, protein synthesis, and cell proliferation
ME Fernandez-Sanchez, T Gonatopoulos-Pournatzis, G Preston, ...
Molecular and cellular biology, 2009
672009
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