Caspase-6 is the direct activator of caspase-8 in the cytochrome c-induced apoptosis pathway: absolute requirement for removal of caspase-6 prodomain V Cowling, J Downward Cell Death & Differentiation 9 (10), 1046-1056, 2002 | 342 | 2002 |
Regulation of mRNA cap methylation VH Cowling Biochemical Journal 425 (2), 295-302, 2010 | 295 | 2010 |
Cap-binding complex (CBC) T Gonatopoulos-Pournatzis, VH Cowling Biochemical Journal 457 (2), 231-242, 2014 | 228 | 2014 |
Mechanism of transcriptional activation by the Myc oncoproteins VH Cowling, MD Cole Seminars in cancer biology 16 (4), 242-252, 2006 | 217 | 2006 |
Transcription-independent functions of MYC: regulation of translation and DNA replication MD Cole, VH Cowling Nature reviews Molecular cell biology 9 (10), 810-815, 2008 | 197 | 2008 |
mRNA cap regulation in mammalian cell function and fate A Galloway, VH Cowling Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1862 (3), 270-279, 2019 | 193 | 2019 |
The Myc transactivation domain promotes global phosphorylation of the RNA polymerase II carboxy-terminal domain independently of direct DNA binding VH Cowling, MD Cole Molecular and cellular biology 27 (6), 2059-2073, 2007 | 192 | 2007 |
Single cell tuning of Myc expression by antigen receptor signal strength and interleukin‐2 in T lymphocytes GC Preston, LV Sinclair, A Kaskar, JL Hukelmann, MN Navarro, I Ferrero, ... The EMBO journal 34 (15), 2008-2024, 2015 | 162 | 2015 |
A core MYC gene expression signature is prominent in basal-like breast cancer but only partially overlaps the core serum response S Chandriani, E Frengen, VH Cowling, SA Pendergrass, CM Perou, ... PloS one 4 (8), e6693, 2009 | 162 | 2009 |
Binding specificity and regulation of the serine protease and PDZ domains of HtrA2/Omi LM Martins, BE Turk, V Cowling, A Borg, ET Jarrell, LC Cantley, ... Journal of Biological Chemistry 278 (49), 49417-49427, 2003 | 161 | 2003 |
Nestin is expressed in the basal/myoepithelial layer of the mammary gland and is a selective marker of basal epithelial breast tumors H Li, P Cherukuri, N Li, V Cowling, M Spinella, M Cole, AK Godwin, ... Cancer research 67 (2), 501-510, 2007 | 150 | 2007 |
Involvement of MINK, a Ste20 family kinase, in Ras oncogene-induced growth arrest in human ovarian surface epithelial cells B Nicke, J Bastien, SJ Khanna, PH Warne, V Cowling, SJ Cook, G Peters, ... Molecular cell 20 (5), 673-685, 2005 | 150 | 2005 |
A conserved Myc protein domain, MBIV, regulates DNA binding, apoptosis, transformation, and G2 arrest VH Cowling, S Chandriani, ML Whitfield, MD Cole Molecular and cellular biology, 2006 | 143 | 2006 |
c-Myc transforms human mammary epithelial cells through repression of the Wnt inhibitors DKK1 and SFRP1 VH Cowling, CM D'Cruz, LA Chodosh, MD Cole Molecular and cellular biology 27 (14), 5135-5146, 2007 | 131 | 2007 |
SINE transcription by RNA polymerase III is suppressed by histone methylation but not by DNA methylation D Varshney, J Vavrova-Anderson, AJ Oler, VH Cowling, BR Cairns, ... Nature communications 6 (1), 6569, 2015 | 89 | 2015 |
RAM/Fam103a1 is required for mRNA cap methylation T Gonatopoulos-Pournatzis, S Dunn, R Bounds, VH Cowling Molecular cell 44 (4), 585-596, 2011 | 86 | 2011 |
Specific regulation of mRNA cap methylation by the c-Myc and E2F1 transcription factors MD Cole, VH Cowling Oncogene 28 (9), 1169-1175, 2009 | 86 | 2009 |
E-cadherin repression contributes to c-Myc-induced epithelial cell transformation VH Cowling, MD Cole Oncogene 26 (24), 3582-3586, 2007 | 80 | 2007 |
Enhanced mRNA cap methylation increases cyclin D1 expression and promotes cell transformation VH Cowling Oncogene 29 (6), 930-936, 2010 | 75 | 2010 |
S-adenosyl homocysteine hydrolase is required for Myc-induced mRNA cap methylation, protein synthesis, and cell proliferation ME Fernandez-Sanchez, T Gonatopoulos-Pournatzis, G Preston, ... Molecular and cellular biology, 2009 | 67 | 2009 |