Dissecting transcriptomic signatures of neuronal differentiation and maturation using iPSCs EE Burke, JG Chenoweth, JH Shin, L Collado-Torres, SK Kim, N Micali, ... Nature communications 11 (1), 462, 2020 | 111 | 2020 |
Psychiatric risk gene transcription factor 4 regulates intrinsic excitability of prefrontal neurons via repression of SCN10a and KCNQ1 MD Rannals, GR Hamersky, SC Page, MN Campbell, A Briley, RA Gallo, ... Neuron 90 (1), 43-55, 2016 | 93 | 2016 |
A myelin-related transcriptomic profile is shared by Pitt–Hopkins syndrome models and human autism spectrum disorder BDN Phan, JF Bohlen, BA Davis, Z Ye, HY Chen, B Mayfield, SR Sripathy, ... Nature neuroscience 23 (3), 375-385, 2020 | 91 | 2020 |
Transcriptional alterations in dorsolateral prefrontal cortex and nucleus accumbens implicate neuroinflammation and synaptic remodeling in opioid use disorder ML Seney, SM Kim, JR Glausier, MA Hildebrand, X Xue, W Zong, J Wang, ... Biological psychiatry 90 (8), 550-562, 2021 | 89 | 2021 |
Evolutionary constraint and innovation across hundreds of placental mammals MJ Christmas, IM Kaplow, DP Genereux, MX Dong, GM Hughes, X Li, ... Science 380 (6643), eabn3943, 2023 | 76 | 2023 |
dotdotdot: an automated approach to quantify multiplex single molecule fluorescent in situ hybridization (smFISH) images in complex tissues KR Maynard, M Tippani, Y Takahashi, BDN Phan, TM Hyde, AE Jaffe, ... Nucleic acids research 48 (11), e66-e66, 2020 | 58 | 2020 |
The schizophrenia-and autism-associated gene, transcription factor 4 regulates the columnar distribution of layer 2/3 prefrontal pyramidal neurons in an activity-dependent manner SC Page, GR Hamersky, RA Gallo, MD Rannals, NE Calcaterra, ... Molecular psychiatry 23 (2), 304, 2017 | 53 | 2017 |
A genomic timescale for placental mammal evolution NM Foley, VC Mason, AJ Harris, KR Bredemeyer, J Damas, HA Lewin, ... Science 380 (6643), eabl8189, 2023 | 47 | 2023 |
Integrating gene annotation with orthology inference at scale BM Kirilenko, C Munegowda, E Osipova, D Jebb, V Sharma, M Blumer, ... Science 380 (6643), eabn3107, 2023 | 42 | 2023 |
BDNF-TrkB signaling in oxytocin neurons contributes to maternal behavior KR Maynard, JW Hobbs, BDN Phan, A Gupta, S Rajpurohit, C Williams, ... eLIFE, 250332, 2018 | 40 | 2018 |
Leveraging base-pair mammalian constraint to understand genetic variation and human disease PF Sullivan, JRS Meadows, S Gazal, BDN Phan, X Li, DP Genereux, ... Science 380 (6643), eabn2937, 2023 | 39 | 2023 |
Three-dimensional genome rewiring in loci with human accelerated regions KC Keough, S Whalen, F Inoue, PF Przytycki, T Fair, C Deng, M Steyert, ... Science 380 (6643), eabm1696, 2023 | 28 | 2023 |
Insights into mammalian TE diversity through the curation of 248 genome assemblies AB Osmanski, NS Paulat, J Korstian, JR Grimshaw, M Halsey, ... Science 380 (6643), eabn1430, 2023 | 27 | 2023 |
Mammalian evolution of human cis-regulatory elements and transcription factor binding sites G Andrews, K Fan, HE Pratt, N Phalke, Zoonomia Consortium §, ... Science 380 (6643), eabn7930, 2023 | 26 | 2023 |
Relating enhancer genetic variation across mammals to complex phenotypes using machine learning IM Kaplow, AJ Lawler, DE Schäffer, C Srinivasan, HH Sestili, ME Wirthlin, ... Science 380 (6643), eabm7993, 2023 | 26 | 2023 |
The contribution of historical processes to contemporary extinction risk in placental mammals AP Wilder, MA Supple, A Subramanian, A Mudide, R Swofford, ... Science 380 (6643), eabn5856, 2023 | 24 | 2023 |
The functional and evolutionary impacts of human-specific deletions in conserved elements JR Xue, A Mackay-Smith, K Mouri, MF Garcia, MX Dong, JF Akers, ... Science 380 (6643), eabn2253, 2023 | 18 | 2023 |
Addiction-associated genetic variants implicate brain cell type-and region-specific cis-regulatory elements in addiction neurobiology C Srinivasan, BDN Phan, AJ Lawler, E Ramamurthy, M Kleyman, ... Journal of Neuroscience 41 (43), 9008-9030, 2021 | 18 | 2021 |
Molecular rhythm alterations in prefrontal cortex and nucleus accumbens associated with opioid use disorder X Xue, W Zong, JR Glausier, SM Kim, MA Shelton, BDN Phan, ... Translational Psychiatry 12 (1), 123, 2022 | 15 | 2022 |
Machine learning sequence prioritization for cell type-specific enhancer design AJ Lawler, E Ramamurthy, AR Brown, N Shin, Y Kim, N Toong, IM Kaplow, ... Elife 11, e69571, 2022 | 13 | 2022 |