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Yasmeen Abouelhassan
Yasmeen Abouelhassan
Adresse e-mail validée de ufl.edu
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Halogenated Phenazines that Potently Eradicate Biofilms, MRSA Persister Cells in Non‐Biofilm Cultures, and Mycobacterium tuberculosis
AT Garrison, Y Abouelhassan, D Kallifidas, F Bai, M Ukhanova, V Mai, ...
Angewandte Chemie 127 (49), 15032-15036, 2015
922015
Discovery of quinoline small molecules with potent dispersal activity against methicillin-resistant Staphylococcus aureus and Staphylococcus epidermidis biofilms using a …
Y Abouelhassan, AT Garrison, GM Burch, W Wong, VM Norwood IV, ...
Bioorganic & Medicinal Chemistry Letters 24 (21), 5076-5080, 2014
862014
Structure–activity relationships of a diverse class of halogenated phenazines that targets persistent, antibiotic-tolerant bacterial biofilms and Mycobacterium tuberculosis
AT Garrison, Y Abouelhassan, VM Norwood IV, D Kallifidas, F Bai, ...
Journal of Medicinal Chemistry 59 (8), 3808-3825, 2016
772016
Recent progress in natural-product-inspired programs aimed to address antibiotic resistance and tolerance
Y Abouelhassan, AT Garrison, H Yang, A Chávez-Riveros, GM Burch, ...
Journal of medicinal chemistry 62 (17), 7618-7642, 2019
752019
Nitroxoline: a broad-spectrum biofilm-eradicating agent against pathogenic bacteria
Y Abouelhassan, Q Yang, H Yousaf, MT Nguyen, M Rolfe, GS Schultz, ...
International journal of antimicrobial agents 49 (2), 247-251, 2017
662017
An efficient Buchwald–Hartwig/reductive cyclization for the scaffold diversification of halogenated phenazines: potent antibacterial targeting, biofilm eradication, and prodrug …
AT Garrison, Y Abouelhassan, D Kallifidas, H Tan, YS Kim, S Jin, ...
Journal of Medicinal Chemistry 61 (9), 3962-3983, 2018
512018
Bromophenazine derivatives with potent inhibition, dispersion and eradication activities against Staphylococcus aureus biofilms
AT Garrison, F Bai, Y Abouelhassan, NG Paciaroni, S Jin, RW Huigens III
Rsc Advances 5 (2), 1120-1124, 2015
512015
A highly potent class of halogenated phenazine antibacterial and biofilm-eradicating agents accessed through a modular Wohl-Aue synthesis
H Yang, Y Abouelhassan, GM Burch, D Kallifidas, G Huang, H Yousaf, ...
Scientific Reports 7 (1), 2003, 2017
472017
Transcript profiling of MRSA biofilms treated with a halogenated phenazine eradicating agent: a platform for defining cellular targets and pathways critical to biofilm survival
Y Abouelhassan, Y Zhang, S Jin, RW Huigens III
Angewandte Chemie International Edition 57 (47), 15523-15528, 2018
422018
Antimicrobial peptide-inspired NH125 analogues: bacterial and fungal biofilm-eradicating agents and rapid killers of MRSA persisters
A Basak, Y Abouelhassan, R Zuo, H Yousaf, Y Ding, RW Huigens
Organic & biomolecular chemistry 15 (26), 5503-5512, 2017
422017
Synthetically tuning the 2‐position of halogenated quinolines: Optimizing antibacterial and biofilm eradication activities via alkylation and reductive amination pathways
A Basak, Y Abouelhassan, VM Norwood IV, F Bai, MT Nguyen, S Jin, ...
Chemistry–A European Journal 22 (27), 9181-9189, 2016
392016
Halogenated quinolines discovered through reductive amination with potent eradication activities against MRSA, MRSE and VRE biofilms
A Basak, Y Abouelhassan, RW Huigens III
Organic & Biomolecular Chemistry 13 (41), 10290-10294, 2015
372015
A phytochemical–halogenated quinoline combination therapy strategy for the treatment of pathogenic bacteria
Y Abouelhassan, AT Garrison, F Bai, VM Norwood IV, MT Nguyen, S Jin, ...
ChemMedChem 10 (7), 1157-1162, 2015
362015
Phenazine Antibiotic‐Inspired Discovery of Bacterial Biofilm‐Eradicating Agents
RW Huigens III, Y Abouelhassan, H Yang
ChemBioChem 20 (23), 2885-2902, 2019
302019
Microwave-enhanced Friedländer synthesis for the rapid assembly of halogenated quinolines with antibacterial and biofilm eradication activities against drug resistant and …
AT Garrison, Y Abouelhassan, H Yang, HH Yousaf, TJ Nguyen, ...
MedChemComm 8 (4), 720-724, 2017
262017
Identification of N‐Arylated NH125 Analogues as Rapid Eradicating Agents against MRSA Persister Cells and Potent Biofilm Killers of Gram‐Positive Pathogens
Y Abouelhassan, A Basak, H Yousaf, RW Huigens III
ChemBioChem 18 (4), 352-357, 2017
252017
A Modular Synthetic Route Involving N-Aryl-2-nitrosoaniline Intermediates Leads to a New Series of 3-Substituted Halogenated Phenazine Antibacterial Agents
H Yang, S Kundra, M Chojnacki, K Liu, MA Fuse, Y Abouelhassan, ...
Journal of medicinal chemistry 64 (11), 7275-7295, 2021
212021
Halogenated quinolines bearing polar functionality at the 2-position: Identification of new antibacterial agents with enhanced activity against Staphylococcus epidermidis
A Basak, Y Abouelhassan, YS Kim, VM Norwood IV, S Jin, RW Huigens III
European Journal of Medicinal Chemistry 155, 705-713, 2018
162018
Plasma and cerebrospinal fluid concentrations of cefiderocol during successful treatment of carbapenem-resistant Acinetobacter baumannii meningitis
WD Kufel, Y Abouelhassan, JM Steele, RL Gutierrez, T Perwez, ...
Journal of Antimicrobial Chemotherapy 77 (10), 2737-2741, 2022
142022
Recent advances in the synthesis of acridines and phenazines
Y Xiao, W Hu, S Sun, JT Yu, J Cheng
Synlett 30 (19), 2113-2122, 2019
132019
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