| Extracellular vesicles: composition, biological relevance, and methods of study MŁP Zaborowski, L Balaj, XO Breakefield, CP Lai Bioscience 65 (8), 783-797, 2015 | 1066 | 2015 |
| Dynamic Biodistribution of Extracellular Vesicles in Vivo Using a Multimodal Imaging Reporter CP Lai, O Mardini, M Ericsson, S Prabhakar, CA Maguire, JW Chen, ... ACS nano 8 (1), 483-494, 2014 | 786 | 2014 |
| Obstacles and opportunities in the functional analysis of extracellular vesicle RNA–an ISEV position paper B Mateescu, EJK Kowal, BWM van Balkom, S Bartel, SN Bhattacharyya, ... Journal of extracellular vesicles 6 (1), 1286095, 2017 | 701 | 2017 |
| Visualization and tracking of tumour extracellular vesicle delivery and RNA translation using multiplexed reporters CP Lai, EY Kim, CE Badr, R Weissleder, TR Mempel, BA Tannous, ... Nature communications 6 (1), 7029, 2015 | 554 | 2015 |
| Role of Exosomes/Microvesicles in the Nervous System and Use in Emerging Therapies CPK Lai, XO Breakefield Frontiers in Physiology 3, 2012 | 348 | 2012 |
| Imaging extracellular vesicles: current and emerging methods STY Chuo, JCY Chien, CPK Lai Journal of biomedical science 25, 1-10, 2018 | 335 | 2018 |
| SCS macrophages suppress melanoma by restricting tumor-derived vesicle–B cell interactions F Pucci, C Garris, CP Lai, A Newton, C Pfirschke, C Engblom, D Alvarez, ... Science 352 (6282), 242-246, 2016 | 317 | 2016 |
| Concise review: developing best-practice models for the therapeutic use of extracellular vesicles AT Reiner, KW Witwer, BWM Van Balkom, J De Beer, C Brodie, ... Stem cells translational medicine 6 (8), 1730-1739, 2017 | 306 | 2017 |
| Directly visualized glioblastoma-derived extracellular vesicles transfer RNA to microglia/macrophages in the brain KE Van Der Vos, ER Abels, X Zhang, C Lai, E Carrizosa, D Oakley, ... Neuro-oncology 18 (1), 58-69, 2015 | 296 | 2015 |
| Selective inhibition of Cx43 hemichannels by Gap19 and its impact on myocardial ischemia/reperfusion injury N Wang, E De Vuyst, R Ponsaerts, K Boengler, N Palacios-Prado, ... Basic research in cardiology 108, 1-16, 2013 | 296 | 2013 |
| Delivery of nitric oxide with a nanocarrier promotes tumour vessel normalization and potentiates anti-cancer therapies YC Sung, PR Jin, LA Chu, FF Hsu, MR Wang, CC Chang, SJ Chiou, ... Nature nanotechnology 14 (12), 1160-1169, 2019 | 284 | 2019 |
| Engineered nanointerfaces for microfluidic isolation and molecular profiling of tumor-specific extracellular vesicles E Reátegui, KE Van Der Vos, CP Lai, M Zeinali, NA Atai, B Aldikacti, ... Nature communications 9 (1), 175, 2018 | 273 | 2018 |
| Ca2+ regulation of connexin 43 hemichannels in C6 glioma and glial cells E De Vuyst, N Wang, E Decrock, M De Bock, M Vinken, M Van Moorhem, ... Cell calcium 46 (3), 176-187, 2009 | 237 | 2009 |
| Tumor-suppressive effects of pannexin 1 in C6 glioma cells CPK Lai, JF Bechberger, RJ Thompson, BA MacVicar, R Bruzzone, ... Cancer research 67 (4), 1545-1554, 2007 | 225 | 2007 |
| Connexin 43 hemichannels contribute to the propagation of apoptotic cell death in a rat C6 glioma cell model E Decrock, E De Vuyst, M Vinken, M Van Moorhem, K Vranckx, N Wang, ... Cell Death & Differentiation 16 (1), 151-163, 2009 | 203 | 2009 |
| The power of imaging to understand extracellular vesicle biology in vivo FJ Verweij, L Balaj, CM Boulanger, DRF Carter, EB Compeer, G D’angelo, ... Nature methods 18 (9), 1013-1026, 2021 | 187 | 2021 |
| Critical considerations for the development of potency tests for therapeutic applications of mesenchymal stromal cell-derived small extracellular vesicles M Gimona, MF Brizzi, ABH Choo, M Dominici, SM Davidson, J Grillari, ... Cytotherapy 23 (5), 373-380, 2021 | 137 | 2021 |
| Delivery of therapeutic proteins via extracellular vesicles: review and potential treatments for Parkinson’s disease, glioma, and schwannoma J Hall, S Prabhakar, L Balaj, CP Lai, RA Cerione, XO Breakefield Cellular and molecular neurobiology 36, 417-427, 2016 | 104 | 2016 |
| Biogenesis, delivery, and function of extracellular RNA JG Patton, JL Franklin, AM Weaver, K Vickers, B Zhang, RJ Coffey, ... Journal of extracellular vesicles 4 (1), 27494, 2015 | 89 | 2015 |
| Glioblastoma hijacks microglial gene expression to support tumor growth SLN Maas, ER Abels, LL Van De Haar, X Zhang, L Morsett, S Sil, ... Journal of neuroinflammation 17, 1-18, 2020 | 87 | 2020 |
Tannous BAMassachusetts General Hospital and Harvard Medical SchoolAdresse e-mail validée de hms.harvard.edu
