| The interaction between N-WASP and the Arp2/3 complex links Cdc42-dependent signals to actin assembly R Rohatgi, L Ma, H Miki, M Lopez, T Kirchhausen, T Takenawa, ... Cell 97 (2), 221-231, 1999 | 1720 | 1999 |
| Patched1 regulates hedgehog signaling at the primary cilium R Rohatgi, L Milenkovic, MP Scott Science 317 (5836), 372-376, 2007 | 1614 | 2007 |
| Mechanism of regulation of WAVE1-induced actin nucleation by Rac1 and Nck S Eden, R Rohatgi, AV Podtelejnikov, M Mann, MW Kirschner Nature 418 (6899), 790-793, 2002 | 1091 | 2002 |
| Mechanism of N-WASP activation by CDC42 and phosphatidylinositol 4, 5-bisphosphate R Rohatgi, HH Ho, MW Kirschner The Journal of cell biology 150 (6), 1299-1310, 2000 | 811 | 2000 |
| Toca-1 mediates Cdc42-dependent actin nucleation by activating the N-WASP-WIP complex HYH Ho, R Rohatgi, AM Lebensohn, L Ma, J Li, SP Gygi, MW Kirschner Cell 118 (2), 203-216, 2004 | 525 | 2004 |
| The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins EW Humke, KV Dorn, L Milenkovic, MP Scott, R Rohatgi Genes & development 24 (7), 670-682, 2010 | 516 | 2010 |
| Nck and phosphatidylinositol 4, 5-bisphosphate synergistically activate actin polymerization through the N-WASP-Arp2/3 pathway R Rohatgi, P Nollau, HYH Ho, MW Kirschner, BJ Mayer Journal of Biological Chemistry 276 (28), 26448-26452, 2001 | 515 | 2001 |
| Structural basis of Smoothened regulation by its extracellular domains EFX Byrne, R Sircar, PS Miller, G Hedger, G Luchetti, S Nachtergaele, ... Nature 535 (7613), 517-522, 2016 | 354 | 2016 |
| WIP regulates N-WASP-mediated actin polymerization and filopodium formation N Martinez-Quiles, R Rohatgi, IM Antón, M Medina, SP Saville, H Miki, ... Nature cell biology 3 (5), 484-491, 2001 | 352 | 2001 |
| Hedgehog signal transduction by Smoothened: pharmacologic evidence for a 2-step activation process R Rohatgi, L Milenkovic, RB Corcoran, MP Scott Proceedings of the National Academy of Sciences 106 (9), 3196-3201, 2009 | 350 | 2009 |
| A single N‐terminal phosphomimic disrupts TDP‐43 polymerization, phase separation, and RNA splicing A Wang, AE Conicella, HB Schmidt, EW Martin, SN Rhoads, AN Reeb, ... The EMBO journal 37 (5), e97452, 2018 | 327 | 2018 |
| Oxysterols are allosteric activators of the oncoprotein Smoothened S Nachtergaele, LK Mydock, K Krishnan, J Rammohan, PH Schlesinger, ... Nature chemical biology 8 (2), 211-220, 2012 | 319 | 2012 |
| Lateral transport of Smoothened from the plasma membrane to the membrane of the cilium L Milenkovic, MP Scott, R Rohatgi Journal of cell biology 187 (3), 365-374, 2009 | 315 | 2009 |
| Dynamic remodeling of membrane composition drives cell cycle through primary cilia excision SC Phua, S Chiba, M Suzuki, E Su, EC Roberson, GV Pusapati, M Setou, ... Cell 168 (1), 264-279. e15, 2017 | 307 | 2017 |
| Cancer risk after use of recombinant bone morphogenetic protein-2 for spinal arthrodesis EJ Carragee, G Chu, R Rohatgi, EL Hurwitz, BK Weiner, ST Yoon, ... JBJS 95 (17), 1537-1545, 2013 | 295 | 2013 |
| The Arp2/3 complex mediates actin polymerization induced by the small GTP-binding protein Cdc42 LE Ma, R Rohatgi, MW Kirschner Proceedings of the National Academy of Sciences 95 (26), 15362-15367, 1998 | 282 | 1998 |
| TDP-43 α-helical structure tunes liquid–liquid phase separation and function AE Conicella, GL Dignon, GH Zerze, HB Schmidt, AM D’Ordine, YC Kim, ... Proceedings of the National Academy of Sciences 117 (11), 5883-5894, 2020 | 267 | 2020 |
| Gli protein activity is controlled by multisite phosphorylation in vertebrate Hedgehog signaling P Niewiadomski, JH Kong, R Ahrends, Y Ma, EW Humke, S Khan, ... Cell reports 6 (1), 168-181, 2014 | 262 | 2014 |
| Patching the gaps in Hedgehog signalling R Rohatgi, MP Scott Nature cell biology 9 (9), 1005-1009, 2007 | 251 | 2007 |
| Cholesterol activates the G-protein coupled receptor Smoothened to promote Hedgehog signaling G Luchetti, R Sircar, JH Kong, S Nachtergaele, A Sagner, EFX Byrne, ... Elife 5, e20304, 2016 | 227 | 2016 |
