Tn-seq: high-throughput parallel sequencing for fitness and genetic interaction studies in microorganisms T Van Opijnen, KL Bodi, A Camilli Nature methods 6 (10), 767-772, 2009 | 964 | 2009 |
Transposon insertion sequencing: a new tool for systems-level analysis of microorganisms T Van Opijnen, A Camilli Nature Reviews Microbiology 11 (7), 435-442, 2013 | 550 | 2013 |
A decade of advances in transposon-insertion sequencing AK Cain, L Barquist, AL Goodman, IT Paulsen, J Parkhill, T van Opijnen Nature Reviews Genetics 21 (9), 526-540, 2020 | 274 | 2020 |
A fine scale phenotype–genotype virulence map of a bacterial pathogen T van Opijnen, A Camilli Genome research 22 (12), 2541-2551, 2012 | 248 | 2012 |
Control of Virulence by Small RNAs in Streptococcus pneumoniae B Mann, T van Opijnen, J Wang, C Obert, YD Wang, R Carter, ... PLoS pathogens 8 (7), e1002788, 2012 | 177 | 2012 |
High temperatures eliminate Wolbachia, a cytoplasmic incompatibility inducing endosymbiont, from the two-spotted spider mite T Van Opijnen, JAJ Breeuwer Experimental & applied acarology 23, 871-881, 1999 | 152 | 1999 |
Genome‐Wide Fitness and Genetic Interactions Determined by Tn‐seq, a High‐Throughput Massively Parallel Sequencing Method for Microorganisms: Emerging Technologies T van Opijnen, DW Lazinski, A Camilli Current protocols in microbiology 36 (1), 1E. 3.1-1E. 3.24, 2015 | 119 | 2015 |
Human immunodeficiency virus type 1 subtypes have a distinct long terminal repeat that determines the replication rate in a host-cell-specific manner T van Opijnen, RE Jeeninga, MC Boerlijst, GP Pollakis, V Zetterberg, ... Journal of virology 78 (7), 3675-3683, 2004 | 118 | 2004 |
AFLP fingerprinting for assessing intraspecific variation and genome mapping in mites AR Weeks, T Van Opijnen, JAJ Breeuwer Experimental & applied acarology 24, 775-793, 2000 | 80 | 2000 |
Elevated CO2 improves both lipid accumulation and growth rate in the glucose-6-phosphate dehydrogenase engineered Phaeodactylum tricornutum S Wu, W Gu, A Huang, Y Li, M Kumar, PE Lim, L Huan, S Gao, G Wang Microbial cell factories 18, 1-16, 2019 | 73* | 2019 |
Dielectrophoresis assisted rapid, selective and single cell detection of antibiotic resistant bacteria with G-FETs N Kumar, W Wang, JC Ortiz-Marquez, M Catalano, M Gray, N Biglari, ... Biosensors and Bioelectronics 156, 112123, 2020 | 71 | 2020 |
Genome‐wide fitness and genetic interactions determined by Tn‐seq, a high‐throughput massively parallel sequencing method for microorganisms T Van Opijnen, DW Lazinski, A Camilli Current protocols in molecular biology 106 (1), 7.16. 1-7.16. 24, 2014 | 71 | 2014 |
Genomic analyses of pneumococci from children with sickle cell disease expose host-specific bacterial adaptations and deficits in current interventions R Carter, J Wolf, T Van Opijnen, M Muller, C Obert, C Burnham, B Mann, ... Cell host & microbe 15 (5), 587-599, 2014 | 70 | 2014 |
Antibiotic susceptibility signatures identify potential antimicrobial targets in the Acinetobacter baumannii cell envelope E Geisinger, NJ Mortman, Y Dai, M Cokol, S Syal, A Farinha, DG Fisher, ... Nature communications 11 (1), 4522, 2020 | 66 | 2020 |
The human immunodeficiency virus type 1 promoter contains a CATA box instead of a TATA box for optimal transcription and replication T Van Opijnen, J Kamoschinski, RE Jeeninga, B Berkhout Journal of virology 78 (13), 6883-6890, 2004 | 66 | 2004 |
Droplet Tn-Seq combines microfluidics with Tn-Seq for identifying complex single-cell phenotypes D Thibault, PA Jensen, S Wood, C Qabar, S Clark, MG Shainheit, ... Nature Communications 10 (1), 5729, 2019 | 62 | 2019 |
Antibiotics disrupt coordination between transcriptional and phenotypic stress responses in pathogenic bacteria PA Jensen, Z Zhu, T van Opijnen Cell reports 20 (7), 1705-1716, 2017 | 62 | 2017 |
Phage display of dynamic covalent binding motifs enables facile development of targeted antibiotics KA McCarthy, MA Kelly, K Li, S Cambray, AS Hosseini, T van Opijnen, ... Journal of the American Chemical Society 140 (19), 6137-6145, 2018 | 60 | 2018 |
Strain dependent genetic networks for antibiotic-sensitivity in a bacterial pathogen with a large pan-genome T van Opijnen, S Dedrick, J Bento PLoS pathogens 12 (9), e1005869, 2016 | 58 | 2016 |
Bacterial factors required for transmission of Streptococcus pneumoniae in mammalian hosts HM Rowe, E Karlsson, H Echlin, TC Chang, L Wang, T van Opijnen, ... Cell host & microbe 25 (6), 884-891. e6, 2019 | 55 | 2019 |