Mathieu Laplante
Mathieu Laplante
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mTOR signaling in growth control and disease
M Laplante, DM Sabatini
cell 149 (2), 274-293, 2012
mTOR signaling at a glance
M Laplante, DM Sabatini
Journal of cell science 122 (20), 3589-3594, 2009
Obesity-associated improvements in metabolic profile through expansion of adipose tissue
JY Kim, E Van De Wall, M Laplante, A Azzara, ME Trujillo, SM Hofmann, ...
The Journal of clinical investigation 117 (9), 2621-2637, 2007
DEPTOR is an mTOR inhibitor frequently overexpressed in multiple myeloma cells and required for their survival
TR Peterson, M Laplante, CC Thoreen, Y Sancak, SA Kang, WM Kuehl, ...
Cell 137 (5), 873-886, 2009
Regulation of mTORC1 and its impact on gene expression at a glance
M Laplante, DM Sabatini
Journal of cell science 126 (8), 1713-1719, 2013
An emerging role of mTOR in lipid biosynthesis
M Laplante, DM Sabatini
Current biology 19 (22), R1046-R1052, 2009
A transgenic mouse with a deletion in the collagenous domain of adiponectin displays elevated circulating adiponectin and improved insulin sensitivity
TP Combs, UB Pajvani, AH Berg, Y Lin, LA Jelicks, M Laplante, ...
Endocrinology 145 (1), 367-383, 2004
mTORC1 controls fasting-induced ketogenesis and its modulation by ageing
S Sengupta, TR Peterson, M Laplante, S Oh, DM Sabatini
Nature 468 (7327), 1100-1104, 2010
mTOR signaling
M Laplante, DM Sabatini
Cold Spring Harbor perspectives in biology 4 (2), a011593, 2012
The roles of mTOR complexes in lipid metabolism
A Caron, D Richard, M Laplante
Annual review of nutrition 35, 321-348, 2015
Connecting mTORC1 signaling to SREBP-1 activation
I Bakan, M Laplante
Current opinion in lipidology 23 (3), 226-234, 2012
In vivo measurement of energy substrate contribution to cold‐induced brown adipose tissue thermogenesis
SM Labbé, A Caron, I Bakan, M Laplante, AC Carpentier, R Lecomte, ...
The FASEB Journal 29 (5), 2046-2058, 2015
PPAR-γ Activation Mediates Adipose Depot− Specific Effects on Gene Expression and Lipoprotein Lipase Activity: Mechanisms for Modulation of Postprandial Lipemia and …
M Laplante, H Sell, KL MacNaul, D Richard, JP Berger, Y Deshaies
Diabetes 52 (2), 291-299, 2003
PPARγ agonism increases rat adipose tissue lipolysis, expression of glyceride lipases, and the response of lipolysis to hormonal control
WT Festuccia, M Laplante, M Berthiaume, Y Gelinas, Y Deshaies
Diabetologia 49, 2427-2436, 2006
A comparative perspective on lipid storage in animals
K Birsoy, WT Festuccia, M Laplante
Journal of cell science 126 (7), 1541-1552, 2013
A Mitofusin-2–dependent inactivating cleavage of Opa1 links changes in mitochondria cristae and ER contacts in the postprandial liver
A Sood, DV Jeyaraju, J Prudent, A Caron, P Lemieux, HM McBride, ...
Proceedings of the National Academy of Sciences 111 (45), 16017-16022, 2014
Mechanisms of the depot specificity of peroxisome proliferator–activated receptor γ action on adipose tissue metabolism
M Laplante, WT Festuccia, G Soucy, Y Gélinas, J Lalonde, JP Berger, ...
Diabetes 55 (10), 2771-2778, 2006
mTORC1 activates SREBP-1c and uncouples lipogenesis from gluconeogenesis
M Laplante, DM Sabatini
Proceedings of the National Academy of Sciences 107 (8), 3281-3282, 2010
The oncometabolite 2-hydroxyglutarate activates the mTOR signalling pathway
M Carbonneau, L M. Gagné, ME Lalonde, MA Germain, A Motorina, ...
Nature communications 7 (1), 12700, 2016
Peroxisome proliferator-activated receptor-γ-mediated positive energy balance in the rat is associated with reduced sympathetic drive to adipose tissues and thyroid status
WT Festuccia, S Oztezcan, M Laplante, M Berthiaume, C Michel, S Dohgu, ...
Endocrinology 149 (5), 2121-2130, 2008
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