| A lethal de novo mutation in the middle domain of the dynamin-related GTPase Drp1 impairs higher order assembly and mitochondrial division CR Chang, CM Manlandro, D Arnoult, J Stadler, AE Posey, RB Hill, ... Journal of biological chemistry 285 (42), 32494-32503, 2010 | 192 | 2010 |
| Phase separation of intrinsically disordered proteins AE Posey, AS Holehouse, RV Pappu Methods in enzymology 611, 1-30, 2018 | 163 | 2018 |
| Arginine-enriched mixed-charge domains provide cohesion for nuclear speckle condensation JA Greig, TA Nguyen, M Lee, AS Holehouse, AE Posey, RV Pappu, ... Molecular cell 77 (6), 1237-1250. e4, 2020 | 147 | 2020 |
| Profilin reduces aggregation and phase separation of huntingtin N-terminal fragments by preferentially binding to soluble monomers and oligomers AE Posey, KM Ruff, TS Harmon, SL Crick, A Li, MI Diamond, RV Pappu Journal of Biological Chemistry 293 (10), 3734-3746, 2018 | 110 | 2018 |
| Self-assembly of block heterochiral peptides into helical tapes TM Clover, CL O’Neill, R Appavu, G Lokhande, AK Gaharwar, AE Posey, ... Journal of the American Chemical Society 142 (47), 19809-19813, 2020 | 60 | 2020 |
| Dilute phase oligomerization can oppose phase separation and modulate material properties of a ribonucleoprotein condensate I Seim, AE Posey, WT Snead, BM Stormo, D Klotsa, RV Pappu, ... Proceedings of the National Academy of Sciences 119 (13), e2120799119, 2022 | 51 | 2022 |
| Inhibition of amyloid beta fibril formation by monomeric human transthyretin K Garai, AE Posey, X Li, JN Buxbaum, RV Pappu Protein Science 27 (7), 1252-1261, 2018 | 43 | 2018 |
| Molecular motor Dnm1 synergistically induces membrane curvature to facilitate mitochondrial fission MW Lee, EY Lee, GH Lai, NW Kennedy, AE Posey, W Xian, AL Ferguson, ... ACS central science 3 (11), 1156-1167, 2017 | 33 | 2017 |
| Glycine-Rich Peptides from FUS Have an Intrinsic Ability to Self-Assemble into Fibers and Networked Fibrils: Published as part of the Biochemistry virtual special … M Kar, AE Posey, F Dar, AA Hyman, RV Pappu Biochemistry 60 (43), 3213-3222, 2021 | 26 | 2021 |
| GADIS: Algorithm for designing sequences to achieve target secondary structure profiles of intrinsically disordered proteins TS Harmon, MD Crabtree, SL Shammas, AE Posey, J Clarke, RV Pappu Protein Engineering, Design and Selection 29 (9), 339-346, 2016 | 23 | 2016 |
| Mechanistic inferences from analysis of measurements of protein phase transitions in live cells AE Posey, KM Ruff, JM Lalmansingh, TS Kandola, JJ Lange, R Halfmann, ... Journal of molecular biology 433 (12), 166848, 2021 | 18 | 2021 |
| Quantifying charge state heterogeneity for proteins with multiple ionizable residues MJ Fossat, AE Posey, RV Pappu Biophysical Journal 120 (24), 5438-5453, 2021 | 17 | 2021 |
| A targeted mutation identified through pKa measurements indicates a postrecruitment role for Fis1 in yeast mitochondrial fission M Koppenol-Raab, MC Harwig, AE Posey, JM Egner, KR MacKenzie, ... Journal of Biological Chemistry 291 (39), 20329-20344, 2016 | 16 | 2016 |
| Gold nanoshell assembly on a ferritin protein employed as a bio-template JW Kim, AE Posey, GD Watt, SH Choi, PT Lillehei Journal of Nanoscience and Nanotechnology 10 (3), 1771-1777, 2010 | 14 | 2010 |
| Methods in Enzymology AE Posey, AS Holehouse, RV Pappu Elsevier, Inc 611, 1-30, 2018 | 13 | 2018 |
| Dynamical control enables the formation of demixed biomolecular condensates AZ Lin, KM Ruff, F Dar, A Jalihal, MR King, JM Lalmansingh, AE Posey, ... Nature Communications 14 (1), 7678, 2023 | 10 | 2023 |
| Quantifying coexistence concentrations in multi-component phase-separating systems using analytical HPLC A Bremer, AE Posey, MB Borgia, WM Borcherds, M Farag, RV Pappu, ... Biomolecules 12 (10), 1480, 2022 | 10 | 2022 |
| Sequence-specific interactions determine viscoelasticity and aging dynamics of protein condensates I Alshareedah, WM Borcherds, SR Cohen, A Singh, AE Posey, M Farag, ... bioRxiv, 2023.04. 06.535902, 2023 | 5 | 2023 |
| Uncovering the contributions of charge regulation to the stability of single alpha helices MJ Fossat, AE Posey, RV Pappu Chemphyschem 24 (7), e202200746, 2023 | 5 | 2023 |
| A first glimpse of nucleation of phase transitions in living cells AE Posey, RV Pappu Molecular cell 71 (1), 1-3, 2018 | 2 | 2018 |
Rohit V. PappuGene K. Beare Distinguished Professor of Biomedical Engineering, Washington University in St. LouisVerified email at wustl.edu
