Joseph L Witztum
Joseph L Witztum
Professor of Medicine, University California, San Diego
Verified email at
Cited by
Cited by
Beyond cholesterol
D Steinberg, S Parthasarathy, TE Carew, JC Khoo, JL Witztum
New England Journal of Medicine 320 (14), 915-924, 1989
Atherosclerosis: the road ahead
CK Glass, JL Witztum
Cell 104 (4), 503-516, 2001
Role of oxidized low density lipoprotein in atherogenesis.
JL Witztum, D Steinberg
The Journal of clinical investigation 88 (6), 1785-1792, 1991
Evidence for the presence of oxidatively modified low density lipoprotein in atherosclerotic lesions of rabbit and man.
S Ylä-Herttuala, W Palinski, ME Rosenfeld, S Parthasarathy, TE Carew, ...
The Journal of clinical investigation 84 (4), 1086-1095, 1989
A comprehensive classification system for lipids1
E Fahy, S Subramaniam, HA Brown, CK Glass, AH Merrill, RC Murphy, ...
Journal of lipid research 46 (5), 839-861, 2005
Modification of low density lipoprotein by endothelial cells involves lipid peroxidation and degradation of low density lipoprotein phospholipids.
UP Steinbrecher, S Parthasarathy, DS Leake, JL Witztum, D Steinberg
Proceedings of the National Academy of Sciences 81 (12), 3883-3887, 1984
The oxidation hypothesis of atherosclerosis.
JL Witztum
The lancet 344 (8925), 793-795, 1994
Low density lipoprotein undergoes oxidative modification in vivo.
W Palinski, ME Rosenfeld, S Ylä-Herttuala, GC Gurtner, SS Socher, ...
Proceedings of the National Academy of Sciences 86 (4), 1372-1376, 1989
Autoantibody against oxidised LDL and progression of carotid atherosclerosis
JT Salonen, H Korpela, R Salonen, K Nyyssonen, S Yla-Herttuala, ...
The Lancet 339 (8798), 883-887, 1992
Triglyceride-rich lipoproteins and high-density lipoprotein cholesterol in patients at high risk of cardiovascular disease: evidence and guidance for management
MJ Chapman, HN Ginsberg, P Amarenco, F Andreotti, J Borén, ...
European heart journal 32 (11), 1345-1361, 2011
Lipoprotein management in patients with cardiometabolic risk: consensus conference report from the American Diabetes Association and the American College of Cardiology Foundation
JD Brunzell, M Davidson, CD Furberg, RB Goldberg, BV Howard, ...
Journal of the American College of Cardiology 51 (15), 1512-1524, 2008
Fatty streak formation occurs in human fetal aortas and is greatly enhanced by maternal hypercholesterolemia. Intimal accumulation of low density lipoprotein and its oxidation …
C Napoli, FP D'Armiento, FP Mancini, A Postiglione, JL Witztum, ...
The Journal of clinical investigation 100 (11), 2680-2690, 1997
T lymphocytes from human atherosclerotic plaques recognize oxidized low density lipoprotein.
S Stemme, B Faber, J Holm, O Wiklund, JL Witztum, GK Hansson
Proceedings of the National Academy of Sciences 92 (9), 3893-3897, 1995
Expression of monocyte chemoattractant protein 1 in macrophage-rich areas of human and rabbit atherosclerotic lesions.
S Ylä-Herttuala, BA Lipton, ME Rosenfeld, T Särkioja, T Yoshimura, ...
Proceedings of the national academy of sciences 88 (12), 5252-5256, 1991
Interleukin-4-dependent production of PPAR-γ ligands in macrophages by 12/15-lipoxygenase
JT Huang, JS Welch, M Ricote, CJ Binder, TM Willson, C Kelly, JL Witztum, ...
Nature 400 (6742), 378-382, 1999
Oxidized phospholipids, Lp (a) lipoprotein, and coronary artery disease
S Tsimikas, ES Brilakis, ER Miller, JP McConnell, RJ Lennon, ...
New England Journal of Medicine 353 (1), 46-57, 2005
Structural identification by mass spectrometry of oxidized phospholipids in minimally oxidized low density lipoprotein that induce monocyte/endothelial interactions and …
AD Watson, N Leitinger, M Navab, KF Faull, S Hörkkö, JL Witztum, ...
Journal of Biological Chemistry 272 (21), 13597-13607, 1997
Expression of the peroxisome proliferator-activated receptor γ (PPARγ) in human atherosclerosis and regulation in macrophages by colony stimulating factors and oxidized low …
M Ricote, J Huang, L Fajas, A Li, J Welch, J Najib, JL Witztum, J Auwerx, ...
Proceedings of the National Academy of Sciences 95 (13), 7614-7619, 1998
Innate and acquired immunity in atherogenesis
CJ Binder, MK Chang, PX Shaw, YI Miller, K Hartvigsen, A Dewan, ...
Nature medicine 8 (11), 1218-1226, 2002
Pneumococcal vaccination decreases atherosclerotic lesion formation: molecular mimicry between Streptococcus pneumoniae and oxidized LDL
CJ Binder, S Hörkkö, A Dewan, MK Chang, EP Kieu, CS Goodyear, ...
Nature medicine 9 (6), 736-743, 2003
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