| Protective effect of quercetin on high-fat diet-induced non-alcoholic fatty liver disease in mice is mediated by modulating intestinal microbiota imbalance and related gut … D Porras, E Nistal, S Martínez-Flórez, S Pisonero-Vaquero, JL Olcoz, ... Free Radical Biology and Medicine 102, 188-202, 2017 | 460 | 2017 |
| Diclofenac toxicity to hepatocytes: a role for drug metabolism in cell toxicity R Bort, X Ponsoda, R Jover, MJ Gómez-Lechón, JV Castell Journal of Pharmacology and Experimental Therapeutics 288 (1), 65-72, 1999 | 368 | 1999 |
| Hepatogenic differentiation of human mesenchymal stem cells from adipose tissue in comparison with bone marrow mesenchymal stem cells R Taléns-Visconti, A Bonora, R Jover, V Mirabet, F Carbonell, JV Castell, ... World journal of gastroenterology: WJG 12 (36), 5834, 2006 | 350 | 2006 |
| Human hepatocytes in primary culture: the choice to investigate drug metabolism in man MJ Gomez-Lechon, MT Donato, JV Castell, R Jover Current drug metabolism 5 (5), 443-462, 2004 | 312 | 2004 |
| Human hepatocytes as a tool for studying toxicity and drug metabolism MJ Gomez-Lechon, MT Donato, JV Castell, R Jover Current drug metabolism 4 (4), 292-312, 2003 | 297 | 2003 |
| Inhibition of VEGF expression through blockade of Hif1α and STAT3 signalling mediates the anti-angiogenic effect of melatonin in HepG2 liver cancer cells S Carbajo-Pescador, R Ordoñez, M Benet, R Jover, A García-Palomo, ... British journal of cancer 109 (1), 83-91, 2013 | 293 | 2013 |
| Cytochrome P450 regulation by hepatocyte nuclear factor 4 in human hepatocytes: a study using adenovirus‐mediated antisense targeting R Jover, R Bort, MJ Gómez‐Lechón, JV Castell Hepatology 33 (3), 668-675, 2001 | 280 | 2001 |
| Down‐regulation of human CYP3A4 by the inflammatory signal interleukin 6: molecular mechanism and transcription factors involved R Jover, R Bort, MJ Gómez‐Lechón, JV Castell The FASEB Journal 16 (13), 1-29, 2002 | 279 | 2002 |
| Hepatocyte cell lines: their use, scope and limitations in drug metabolism studies JV Castell, R Jover, CP Martnez-Jimnez, MJ Gmez-Lechn Expert opinion on drug metabolism & toxicology 2 (2), 183-212, 2006 | 276 | 2006 |
| Diclofenac induces apoptosis in hepatocytes by alteration of mitochondrial function and generation of ROS MJ Gómez-Lechón, X Ponsoda, E O’Connor, T Donato, JV Castell, ... Biochemical pharmacology 66 (11), 2155-2167, 2003 | 227 | 2003 |
| Hepatic cytochrome P450 down-regulation during aseptic inflammation in the mouse is interleukin 6 dependent E Siewert, R Bort, R Kluge, PC Heinrich, J Castell, R Jover Hepatology 32 (1), 49-55, 2000 | 223 | 2000 |
| Long‐term expression of differentiated functions in hepatocytes cultured in three‐dimensional collagen matrix MJ Gómez‐Lechón, R Jover, T Donato, X Ponsoda, C Rodriguez, ... Journal of cellular physiology 177 (4), 553-562, 1998 | 196 | 1998 |
| Re-expression of C/EBPα induces CYP2B6, CYP2C9 and CYP2D6 genes in HepG2 cells R Jover, R Bort, MJ Gómez-Lechón, JV Castell FEBS letters 431 (2), 227-230, 1998 | 177 | 1998 |
| Transcriptional regulation and expression of CYP3A4 in hepatocytes CP Martínez-Jiménez, R Jover, M Teresa Donato, JV Castell, ... Current drug metabolism 8 (2), 185-194, 2007 | 175 | 2007 |
| Human mesenchymal stem cells from adipose tissue: differentiation into hepatic lineage R Taléns-Visconti, A Bonora, R Jover, V Mirabet, F Carbonell, JV Castell, ... Toxicology in vitro 21 (2), 324-329, 2007 | 149 | 2007 |
| Transcriptional regulation of human CYP3A4 basal expression by CCAAT enhancer-binding protein α and hepatocyte nuclear factor-3γ C Rodrıguez-Antona, R Bort, R Jover, N Tindberg, M Ingelman-Sundberg, ... Molecular pharmacology 63 (5), 1180-1189, 2003 | 139 | 2003 |
| Cytotoxicity evaluation of the first ten MEIC chemicals: acute lethal toxicity in man predicted by cytotoxicity in five cellular assays and by oral LD50 tests in rodents B Ekwall, I Bondesson, JV Castell, MJ Gómez-Lechón, S Hellberg, ... Alternatives to Laboratory Animals 17 (2), 83-100, 1989 | 135 | 1989 |
| Quantitative RT-PCR measurement of human cytochrome P-450s: application to drug induction studies C Rodríguez-Antona, R Jover, MJ Gómez-Lechón, JV Castell Archives of biochemistry and biophysics 376 (1), 109-116, 2000 | 128 | 2000 |
| Quercetin ameliorates dysregulation of lipid metabolism genes via the PI3K/AKT pathway in a diet‐induced mouse model of nonalcoholic fatty liver disease S Pisonero‐Vaquero, Á Martínez‐Ferreras, MV García‐Mediavilla, ... Molecular Nutrition & Food Research 59 (5), 879-893, 2015 | 127 | 2015 |
| Hepatic cell lines for drug hepatotoxicity testing: limitations and strategies to upgrade their metabolic competence by gene engineering M Teresa Donato, R Jover, M Jose Gomez-Lechon Current drug metabolism 14 (9), 946-968, 2013 | 122 | 2013 |
