Lentiviral-mediated silencing of SOD1 through RNA interference retards disease onset and progression in a mouse model of ALS C Raoul, T Abbas-Terki, JC Bensadoun, S Guillot, G Haase, J Szulc, ... Nature medicine 11 (4), 423-428, 2005 | 582 | 2005 |
Motoneuron death triggered by a specific pathway downstream of Fas: potentiation by ALS-linked SOD1 mutations C Raoul, AG Estévez, H Nishimune, DW Cleveland, O delapeyriere, ... Neuron 35 (6), 1067-1083, 2002 | 544 | 2002 |
Programmed cell death of embryonic motoneurons triggered through the Fas death receptor C Raoul, CE Henderson, B Pettmann The Journal of cell biology 147 (5), 1049-1062, 1999 | 293 | 1999 |
Systemic AAV6 delivery mediating RNA interference against SOD1: neuromuscular transduction does not alter disease progression in fALS mice C Towne, C Raoul, BL Schneider, P Aebischer Molecular Therapy 16 (6), 1018-1025, 2008 | 165 | 2008 |
Active killing of neurons during development and following stress: a role for p75NTR and Fas? C Raoul, B Pettmann, CE Henderson Current opinion in neurobiology 10 (1), 111-117, 2000 | 151 | 2000 |
Chronic activation in presymptomatic amyotrophic lateral sclerosis (ALS) mice of a feedback loop involving Fas, Daxx, and FasL C Raoul, E Buhler, C Sadeghi, A Jacquier, P Aebischer, B Pettmann, ... Proceedings of the National Academy of Sciences 103 (15), 6007-6012, 2006 | 141 | 2006 |
Reduced calreticulin levels link endoplasmic reticulum stress and Fas-triggered cell death in motoneurons vulnerable to ALS N Bernard-Marissal, A Moumen, C Sunyach, C Pellegrino, K Dudley, ... Journal of Neuroscience 32 (14), 4901-4912, 2012 | 119 | 2012 |
Signaling by death receptors in the nervous system G Haase, B Pettmann, C Raoul, CE Henderson Current opinion in neurobiology 18 (3), 284-291, 2008 | 117 | 2008 |
Cytotoxic CD8+ T lymphocytes expressing ALS-causing SOD1 mutant selectively trigger death of spinal motoneurons E Coque, C Salsac, G Espinosa-Carrasco, B Varga, N Degauque, ... Proceedings of the National Academy of Sciences 116 (6), 2312-2317, 2019 | 105 | 2019 |
Vitamin D confers protection to motoneurons and is a prognostic factor of amyotrophic lateral sclerosis W Camu, B Tremblier, C Plassot, S Alphandery, C Salsac, N Pageot, ... Neurobiology of aging 35 (5), 1198-1205, 2014 | 99 | 2014 |
IFNγ triggers a LIGHT-dependent selective death of motoneurons contributing to the non-cell-autonomous effects of mutant SOD1 J Aebischer, P Cassina, B Otsmane, A Moumen, D Seilhean, V Meininger, ... Cell Death & Differentiation 18 (5), 754-768, 2011 | 95 | 2011 |
Olesoxime delays muscle denervation, astrogliosis, microglial activation and motoneuron death in an ALS mouse model C Sunyach, M Michaud, T Arnoux, N Bernard-Marissal, J Aebischer, ... Neuropharmacology 62 (7), 2346-2353, 2012 | 94 | 2012 |
Fas/tumor necrosis factor receptor death signaling is required for axotomy-induced death of motoneurons in vivo G Ugolini, C Raoul, A Ferri, C Haenggeli, Y Yamamoto, D Salaün, ... Journal of Neuroscience 23 (24), 8526-8531, 2003 | 94 | 2003 |
Viral-based modelling and correction of neurodegenerative diseases by RNA interference C Raoul, SD Barker, P Aebischer Gene therapy 13 (6), 487-495, 2006 | 87 | 2006 |
Implication of the JNK pathway in a rat model of Huntington's disease V Perrin, N Dufour, C Raoul, R Hassig, E Brouillet, P Aebischer, ... Experimental neurology 215 (1), 191-200, 2009 | 83 | 2009 |
Wildtype motoneurons, ALS‐Linked SOD1 mutation and glutamate profoundly modify astrocyte metabolism and lactate shuttling B Madji Hounoum, S Mavel, E Coque, F Patin, P Vourc'h, S Marouillat, ... Glia 65 (4), 592-605, 2017 | 66 | 2017 |
Collapsin response mediator protein 4a (CRMP4a) is upregulated in motoneurons of mutant SOD1 mice and can trigger motoneuron axonal degeneration and cell death L Duplan, N Bernard, W Casseron, K Dudley, E Thouvenot, J Honnorat, ... Journal of Neuroscience 30 (2), 785-796, 2010 | 66 | 2010 |
Neuroimmunity dynamics and the development of therapeutic strategies for amyotrophic lateral sclerosis M Bowerman, T Vincent, F Scamps, FE Perrin, W Camu, C Raoul Frontiers in cellular neuroscience 7, 214, 2013 | 64 | 2013 |
AAV‐mediated expression of wild‐type and ALS‐linked mutant VAPB selectively triggers death of motoneurons through a Ca2+‐dependent ER‐associated pathway K Langou, A Moumen, C Pellegrino, J Aebischer, I Medina, P Aebischer, ... Journal of neurochemistry 114 (3), 795-809, 2010 | 64 | 2010 |
Regulation of brain cholesterol: what role do liver X receptors play in neurodegenerative diseases? K Mouzat, A Chudinova, A Polge, J Kantar, W Camu, C Raoul, ... International journal of molecular sciences 20 (16), 3858, 2019 | 59 | 2019 |