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Howard Crawford
Howard Crawford
Adresse e-mail validée de hfhs.org
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Preinvasive and invasive ductal pancreatic cancer and its early detection in the mouse
SR Hingorani, EF Petricoin, A Maitra, V Rajapakse, C King, MA Jacobetz, ...
Cancer cell 4 (6), 437-450, 2003
27582003
The metalloproteinase matrilysin is a target of β-catenin transactivation in intestinal tumors
HC Crawford, BM Fingleton, LA Rudolph-Owen, KJH Goss, B Rubinfeld, ...
Oncogene 18 (18), 2883-2891, 1999
9341999
Release of an invasion promoter E-cadherin fragment by matrilysin and stromelysin-1
V Noë, B Fingleton, K Jacobs, HC Crawford, S Vermeulen, W Steelant, ...
Journal of cell science 114 (1), 111-118, 2001
9192001
Ductal pancreatic cancer modeling and drug screening using human pluripotent stem cell–and patient-derived tumor organoids
L Huang, A Holtzinger, I Jagan, M BeGora, I Lohse, N Ngai, C Nostro, ...
Nature medicine 21 (11), 1364-1371, 2015
7052015
Inhibition of RhoA by p120 catenin
PZ Anastasiadis, SY Moon, MA Thoreson, DJ Mariner, HC Crawford, ...
Nature cell biology 2 (9), 637-644, 2000
6102000
EGF receptor is required for KRAS-induced pancreatic tumorigenesis
CM Ardito, BM Grüner, KK Takeuchi, C Lubeseder-Martellato, ...
Cancer cell 22 (3), 304-317, 2012
5332012
Matrix metalloproteinase-7–dependent release of tumor necrosis factor-α in a model of herniated disc resorption
H Haro, HC Crawford, B Fingleton, K Shinomiya, DM Spengler, ...
The Journal of clinical investigation 105 (2), 143-150, 2000
4962000
Osteopontin, a novel substrate for matrix metalloproteinase-3 (stromelysin-1) and matrix metalloproteinase-7 (matrilysin)
R Agnihotri, HC Crawford, H Haro, LM Matrisian, MC Havrda, L Liaw
Journal of Biological Chemistry 276 (30), 28261-28267, 2001
4932001
The p120 ctn -binding partner Kaiso is a bi-modal DNA-binding protein that recognizes both a sequence-specific consensus and methylated CpG …
JM Daniel, CM Spring, HC Crawford, AB Reynolds, A Baig
Nucleic acids research 30 (13), 2911-2919, 2002
3502002
NRF2 promotes tumor maintenance by modulating mRNA translation in pancreatic cancer
IIC Chio, SM Jafarnejad, M Ponz-Sarvise, Y Park, K Rivera, W Palm, ...
Cell 166 (4), 963-976, 2016
3482016
Adipogenesis is inhibited by brief, daily exposure to high-frequency, extremely low-magnitude mechanical signals
CT Rubin, E Capilla, YK Luu, B Busa, H Crawford, DJ Nolan, V Mittal, ...
Proceedings of the National Academy of Sciences 104 (45), 17879-17884, 2007
3292007
Macrophage-released pyrimidines inhibit gemcitabine therapy in pancreatic cancer
CJ Halbrook, C Pontious, I Kovalenko, L Lapienyte, S Dreyer, HJ Lee, ...
Cell metabolism 29 (6), 1390-1399. e6, 2019
3252019
Macrophage-secreted cytokines drive pancreatic acinar-to-ductal metaplasia through NF-κB and MMPs
GY Liou, H Döppler, B Necela, M Krishna, HC Crawford, M Raimondo, ...
Journal of Cell Biology 202 (3), 563-577, 2013
2902013
Ablation of sensory neurons in a genetic model of pancreatic ductal adenocarcinoma slows initiation and progression of cancer
JL Saloman, KM Albers, D Li, DJ Hartman, HC Crawford, EA Muha, ...
Proceedings of the National Academy of Sciences 113 (11), 3078-3083, 2016
2842016
Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer
Y Song, MK Washington, HC Crawford
Cancer research 70 (5), 2115-2125, 2010
2802010
Matrix metalloproteinase-7 is expressed by pancreatic cancer precursors and regulates acinar-to-ductal metaplasia in exocrine pancreas
HC Crawford, CR Scoggins, MK Washington, LM Matrisian, SD Leach
The Journal of clinical investigation 109 (11), 1437-1444, 2002
2782002
Tumor and stromal expression of matrix metalloproteinases and their role in tumor progression.
HC Crawford, LM Matrisian
Invasion & metastasis 14 (1-6), 234-245, 1994
2771994
Mechanisms controlling the transcription of matrix metalloproteinase genes in normal and neoplastic cells
HC Crawford, LM Matrisian
Enzyme and Protein 49 (1-3), 20-37, 1996
2671996
Regulatory T-cell depletion alters the tumor microenvironment and accelerates pancreatic carcinogenesis
Y Zhang, J Lazarus, NG Steele, W Yan, HJ Lee, ZC Nwosu, CJ Halbrook, ...
Cancer discovery 10 (3), 422-439, 2020
2622020
Distinct TCR signaling pathways drive proliferation and cytokine production in T cells
CS Guy, KM Vignali, J Temirov, ML Bettini, AE Overacre, M Smeltzer, ...
Nature immunology 14 (3), 262-270, 2013
2542013
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