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Ruben Pio
Ruben Pio
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Year
Biomarkers in lung cancer screening: achievements, promises, and challenges
LM Seijo, N Peled, D Ajona, M Boeri, JK Field, G Sozzi, R Pio, JJ Zulueta, ...
Journal of Thoracic Oncology 14 (3), 343-357, 2019
3962019
Hypoxia-inducible factor-1 (HIF-1) up-regulates adrenomedullin expression in human tumor cell lines during oxygen deprivation: a possible promotion mechanism of carcinogenesis
M Garayoa, A Martínez, S Lee, R Pío, WG An, L Neckers, J Trepel, ...
Molecular endocrinology 14 (6), 848-862, 2000
3382000
Complement factor H is a serum-binding protein for adrenomedullin, and the resulting complex modulates the bioactivities of both partners
R Pıo, A Martı́nez, EJ Unsworth, JA Kowalak, JA Bengoechea, PF Zipfel, ...
Journal of Biological Chemistry 276 (15), 12292-12300, 2001
3342001
Alternative splicing: an emerging topic in molecular and clinical oncology
MJ Pajares, T Ezponda, R Catena, A Calvo, R Pio, LM Montuenga
The lancet oncology 8 (4), 349-357, 2007
3272007
Anaphylatoxin C5a creates a favorable microenvironment for lung cancer progression
L Corrales, D Ajona, S Rafail, JJ Lasarte, JI Riezu-Boj, JD Lambris, ...
The Journal of Immunology 189 (9), 4674-4683, 2012
2892012
Frequent BRG1/SMARCA4–inactivating mutations in human lung cancer cell lines
PP Medina, OA Romero, T Kohno, LM Montuenga, R Pio, J Yokota, ...
Human mutation 29 (5), 617-622, 2008
2862008
The role of complement in tumor growth
R Pio, L Corrales, JD Lambris
Tumor Microenvironment and Cellular Stress: Signaling, Metabolism, Imaging …, 2014
2372014
Altered patterns of expression of members of the heterogeneous nuclear ribonucleoprotein (hnRNP) family in lung cancer
I Pino, R Pıo, G Toledo, N Zabalegui, S Vicent, N Rey, MD Lozano, ...
Lung cancer 41 (2), 131-143, 2003
2332003
A combined PD-1/C5a blockade synergistically protects against lung cancer growth and metastasis
D Ajona, S Ortiz-Espinosa, H Moreno, T Lozano, MJ Pajares, J Agorreta, ...
Cancer discovery 7 (7), 694-703, 2017
1832017
Complementing the cancer-immunity cycle
R Pio, D Ajona, S Ortiz-Espinosa, A Mantovani, JD Lambris
Frontiers in immunology 10, 445513, 2019
1632019
The effects of adrenomedullin overexpression in breast tumor cells
A Martínez, M Vos, L Guédez, G Kaur, Z Chen, M Garayoa, R Pío, ...
Journal of the National Cancer Institute 94 (16), 1226-1237, 2002
1592002
A gene‐alteration profile of human lung cancer cell lines
R Blanco, R Iwakawa, M Tang, T Kohno, B Angulo, R Pio, LM Montuenga, ...
Human mutation 30 (8), 1199-1206, 2009
1552009
Investigation of complement activation product c4d as a diagnostic and prognostic biomarker for lung cancer
D Ajona, MJ Pajares, L Corrales, JL Perez-Gracia, J Agorreta, MD Lozano, ...
Journal of the National Cancer Institute 105 (18), 1385-1393, 2013
1462013
Novel and natural knockout lung cancer cell lines for the LKB1/STK11 tumor suppressor gene
J Carretero, PP Medina, R Pio, LM Montuenga, M Sanchez-Cespedes
Oncogene 23 (22), 4037-4040, 2004
1442004
Innate immune mediators in cancer: between defense and resistance
P Berraondo, L Minute, D Ajona, L Corrales, I Melero, R Pio
Immunological Reviews 274 (1), 290-306, 2016
1422016
Complement inhibition in cancer therapy
R Pio, D Ajona, JD Lambris
Seminars in immunology 25 (1), 54-64, 2013
1412013
Molecular analysis of a multistep lung cancer model induced by chronic inflammation reveals epigenetic regulation of p16, activation of the DNA damage response pathway
D Blanco, S Vicent, MF Fraga, I Fernandez-Garcia, J Freire, A Lujambio, ...
Neoplasia 9 (10), 840-IN12, 2007
1382007
Expression of complement factor H by lung cancer cells: effects on the activation of the alternative pathway of complement
D Ajona, Z Castano, M Garayoa, E Zudaire, MJ Pajares, A Martinez, ...
Cancer Research 64 (17), 6310-6318, 2004
1362004
A novel epigenetic signature for early diagnosis in lung cancer
A Diaz-Lagares, J Mendez-Gonzalez, D Hervas, M Saigi, MJ Pajares, ...
Clinical Cancer Research 22 (13), 3361-3371, 2016
1352016
Improving selection criteria for lung cancer screening. The potential role of emphysema
P Sanchez-Salcedo, DO Wilson, JP de-Torres, JL Weissfeld, J Berto, ...
American journal of respiratory and critical care medicine 191 (8), 924-931, 2015
1262015
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