Frank Gibbons
Frank Gibbons
Associate Director, Biogen
Adresse e-mail validée de biogen.com
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Towards a proteome-scale map of the human protein–protein interaction network
JF Rual, K Venkatesan, T Hao, T Hirozane-Kishikawa, A Dricot, N Li, ...
Nature 437 (7062), 1173-1178, 2005
31342005
Judging the quality of gene expression-based clustering methods using gene annotation
FD Gibbons, FP Roth
Genome research 12 (10), 1574-1581, 2002
4052002
Intensity-based protein identification by machine learning from a library of tandem mass spectra
JE Elias, FD Gibbons, OD King, FP Roth, SP Gygi
Nature biotechnology 22 (2), 214-219, 2004
3572004
A critical assessment of Mus musculus gene function prediction using integrated genomic evidence
L Peña-Castillo, M Tasan, CL Myers, H Lee, T Joshi, C Zhang, Y Guan, ...
Genome biology 9 (1), 1-19, 2008
2772008
Predicting protein complex membership using probabilistic network reliability
S Asthana, OD King, FD Gibbons, FP Roth
Genome research 14 (6), 1170-1175, 2004
2502004
AZD1208, a potent and selective pan-Pim kinase inhibitor, demonstrates efficacy in preclinical models of acute myeloid leukemia
EK Keeton, K McEachern, KS Dillman, S Palakurthi, Y Cao, MR Grondine, ...
Blood 123 (6), 905-913, 2014
1862014
Discovery of Mcl-1-specific inhibitor AZD5991 and preclinical activity in multiple myeloma and acute myeloid leukemia
AE Tron, MA Belmonte, A Adam, BM Aquila, LH Boise, E Chiarparin, ...
Nature communications 9 (1), 1-14, 2018
1822018
Genomewide identification of Sko1 target promoters reveals a regulatory network that operates in response to osmotic stress in Saccharomyces cerevisiae
M Proft, FD Gibbons, M Copeland, FP Roth, K Struhl
Eukaryotic Cell 4 (8), 1343-1352, 2005
872005
Combining guilt-by-association and guilt-by-profiling to predict Saccharomyces cerevisiae gene function
W Tian, LV Zhang, M Taşan, FD Gibbons, OD King, J Park, Z Wunderlich, ...
Genome biology 9 (1), 1-21, 2008
852008
Chipper: discovering transcription-factor targets from chromatin immunoprecipitation microarrays using variance stabilization
FD Gibbons, M Proft, K Struhl, FP Roth
Genome biology 6 (11), 1-9, 2005
652005
An en masse phenotype and function prediction system for Mus musculus
M Taşan, W Tian, DP Hill, FD Gibbons, JA Blake, FP Roth
Genome biology 9 (1), 1-16, 2008
292008
SILVER helps assign peptides to tandem mass spectra using intensity-based scoring
FD Gibbons, JE Elias, SP Gygi, FP Roth
Journal of the American Society for Mass Spectrometry 15 (6), 910-912, 2004
282004
Methods, systems and products for predicting response of tumor cells to a therapeutic agent and treating a patient according to the predicted response
B Schoeberl, B Harms, FD Gibbons, JB Fitzgerald, MD Onsum, U Nielsen, ...
US Patent App. 12/707,521, 2011
182011
FuncBase: a resource for quantitative gene function annotation
JE Beaver, M Taşan, FD Gibbons, W Tian, TR Hughes, FP Roth
Bioinformatics 26 (14), 1806-1807, 2010
142010
MM-111, an ErbB2/ErbB3 bispecific antibody with potent activity in ErbB2-overexpressing cells, positively combines with trastuzumab to inhibit growth of breast cancer cells …
A Huhalov, S Adams, V Paragas, S Oyama, R Overland, L Luus, ...
Cancer Research 70 (8 Supplement), 3485-3485, 2010
112010
Methods and systems for predicting response of cells to a therapeutic agent
B Schoeberl, B Harms, FD Gibbons, JB Fitzgerald, MD Onsum, U Nielsen, ...
US Patent 8,623,592, 2014
92014
Methods and systems for predicting response of cells to a therapeutic agent
B Schoeberl, B Harms, FD Gibbons, JB Fitzgerald, MD Onsum, U Nielsen, ...
US Patent 8,623,592, 2014
92014
Methods and systems for predicting response of cells to a therapeutic agent
B Schoeberl, B Harms, FD Gibbons, JB Fitzgerald, MD Onsum, U Nielsen, ...
US Patent 8,623,592, 2014
92014
Discovery of a potent and selective oral inhibitor of ERK1/2 (AZD0364) that is efficacious in both monotherapy and combination therapy in models of nonsmall cell lung cancer …
RA Ward, MJ Anderton, P Bethel, J Breed, C Cook, EJ Davies, A Dobson, ...
Journal of medicinal chemistry 62 (24), 11004-11018, 2019
72019
Mixture dynamics: combination therapy in oncology
J Gabrielsson, FD Gibbons, LA Peletier
European Journal of Pharmaceutical Sciences 88, 132-146, 2016
72016
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