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Karien Bloem
Karien Bloem
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Multivalent glycopeptide dendrimers for the targeted delivery of antigens to dendritic cells
JJ García-Vallejo, M Ambrosini, A Overbeek, WE van Riel, K Bloem, ...
Molecular immunology 53 (4), 387-397, 2013
1212013
Systematic comparison of drug-tolerant assays for anti-drug antibodies in a cohort of adalimumab-treated rheumatoid arthritis patients
K Bloem, A van Leeuwen, G Verbeek, MT Nurmohamed, GJ Wolbink, ...
Journal of immunological methods 418, 29-38, 2015
882015
Defining the therapeutic range for adalimumab and predicting response in psoriasis: a multicenter prospective observational cohort study
N Wilkinson, T Tsakok, N Dand, K Bloem, M Duckworth, D Baudry, ...
Journal of Investigative Dermatology 139 (1), 115-123, 2019
692019
Immunogenicity of therapeutic antibodies: monitoring antidrug antibodies in a clinical context
K Bloem, B Hernández-Breijo, A Martínez-Feito, T Rispens
Therapeutic drug monitoring 39 (4), 327-332, 2017
652017
BODIPY-labeled DC-SIGN-targeting glycodendrons efficiently internalize and route to lysosomes in human dendritic cells
R Ribeiro-Viana, JJ Garcia-Vallejo, D Collado, E Perez-Inestrosa, ...
Biomacromolecules 13 (10), 3209-3219, 2012
602012
Ligand binding and signaling of dendritic cell immunoreceptor (DCIR) is modulated by the glycosylation of the carbohydrate recognition domain
K Bloem, IM Vuist, AJ van der Plas, LMJ Knippels, J Garssen, ...
PLoS One 8 (6), e66266, 2013
562013
DCIR interacts with ligands from both endogenous and pathogenic origin
K Bloem, IM Vuist, M van den Berk, EJ Klaver, I van Die, LMJ Knippels, ...
Immunology letters 158 (1-2), 33-41, 2014
542014
Identification and characterization of a complete carnitine biosynthesis pathway in Candida albicans
K Strijbis, CWT Van Roermund, GP Hardy, J Van den Burg, K Bloem, ...
The FASEB Journal 23 (8), 2349-2359, 2009
482009
Capillary blood microsampling to determine serum biopharmaceutical concentration: Mitra® microsampler vs dried blood spot
K Bloem, T Schaap, R Boshuizen, EL Kneepkens, GJ Wolbink, A Vries, ...
Bioanalysis 10 (11), 815-823, 2018
452018
Dynamics of circulating TNF during adalimumab treatment using a drug-tolerant TNF assay
LC Berkhout, MJ l’Ami, J Ruwaard, MH Hart, PO Heer, K Bloem, ...
Science Translational Medicine 11 (477), eaat3356, 2019
422019
The consequences of multiple simultaneous C-type lectin–ligand interactions: DCIR alters the endo-lysosomal routing of DC-SIGN
JJ García-Vallejo, K Bloem, LMJ Knippels, J Garssen, SJ van Vliet, ...
Frontiers in Immunology 6, 132847, 2015
402015
Association of serum ustekinumab levels with clinical response in psoriasis
T Tsakok, N Wilson, N Dand, FC Loeff, K Bloem, D Baudry, M Duckworth, ...
JAMA dermatology 155 (11), 1235-1243, 2019
392019
Dried blood spots from finger prick facilitate therapeutic drug monitoring of adalimumab and anti‐adalimumab in patients with inflammatory diseases
EL Kneepkens, MF Pouw, GJ Wolbink, T Schaap, MT Nurmohamed, ...
British journal of clinical pharmacology 83 (11), 2474-2484, 2017
372017
Interaction of the Capsular Polysaccharide A from Bacteroides fragilis with DC-SIGN on Human Dendritic Cells is Necessary for Its Processing and Presentation to …
K Bloem, JJ García-Vallejo, IM Vuist, BA Cobb, SJ van Vliet, Y Van Kooyk
Frontiers in immunology 4, 103, 2013
372013
Dried blood samples can support monitoring of infliximab concentrations in patients with inflammatory bowel disease: a clinical validation
SE Berends, GRAM D'Haens, T Schaap, A de Vries, T Rispens, K Bloem, ...
British journal of clinical pharmacology 85 (7), 1544-1551, 2019
322019
Toll-like receptor 4 triggering promotes cytosolic routing of DC-SIGN-targeted antigens for presentation on MHC class I
SK Horrevorts, S Duinkerken, K Bloem, P Secades, H Kalay, RJ Musters, ...
Frontiers in immunology 9, 1231, 2018
322018
Predictive value of serum infliximab levels at induction phase in rheumatoid arthritis patients
T Jurado, C Plasencia-Rodríguez, A Martínez-Feito, V Navarro-Compán, ...
The Open Rheumatology Journal 11, 75, 2017
242017
Monitoring of adalimumab concentrations at home in patients with inflammatory bowel disease using dried blood samples
SE Berends, K Bloem, A de Vries, T Schaap, T Rispens, AS Strik, ...
Therapeutic drug monitoring 42 (2), 289-294, 2020
162020
Comprehensive evaluation of microneedle‐based intradermal adalimumab delivery vs. subcutaneous administration: results of a randomized controlled clinical trial
J Jacobse, W Ten Voorde, A Tandon, SG Romeijn, HW Grievink, ...
British journal of clinical pharmacology 87 (8), 3162-3176, 2021
112021
Using real‐world data to guide ustekinumab dosing strategies for psoriasis: a prospective pharmacokinetic‐pharmacodynamic study
S Pan, T Tsakok, N Dand, DO Lonsdale, FC Loeff, K Bloem, A de Vries, ...
Clinical and Translational Science 13 (2), 400-409, 2020
102020
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