Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3483 | 2010 |
Parkinson's disease, pesticides, and glutathione transferase polymorphisms A Menegon, PG Board, AC Blackburn, GD Mellick, DG Le Couteur The Lancet 352 (9137), 1344-1346, 1998 | 422 | 1998 |
Reversal of the glycolytic phenotype by dichloroacetate inhibits metastatic breast cancer cell growth in vitro and in vivo RC Sun, M Fadia, JE Dahlstrom, CR Parish, PG Board, AC Blackburn Breast cancer research and treatment 120, 253-260, 2010 | 324 | 2010 |
Identification of six new susceptibility loci for invasive epithelial ovarian cancer KB Kuchenbaecker, SJ Ramus, J Tyrer, A Lee, HC Shen, J Beesley, ... Nature genetics 47 (2), 164-171, 2015 | 307 | 2015 |
Characterization of the monomethylarsonate reductase and dehydroascorbate reductase activities of Omega class glutathione transferase variants: implications for arsenic … EM Schmuck, PG Board, AK Whitbread, N Tetlow, JA Cavanaugh, ... Pharmacogenetics and Genomics 15 (7), 493-501, 2005 | 178 | 2005 |
Crystal Structure of Maleylacetoacetate Isomerase/Glutathione Transferase Zeta Reveals the Molecular Basis for Its Remarkable Catalytic Promiscuity, G Polekhina, PG Board, AC Blackburn, MW Parker Biochemistry 40 (6), 1567-1576, 2001 | 163 | 2001 |
Targeting metabolism with arsenic trioxide and dichloroacetate in breast cancer cells RC Sun, PG Board, AC Blackburn Molecular cancer 10, 1-15, 2011 | 157 | 2011 |
Discovery of a functional polymorphism in human glutathione transferase zeta by expressed sequence tag database analysis AC Blackburn, HF Tzeng, MW Anders, PG Board Pharmacogenetics and Genomics 10 (1), 49-57, 2000 | 149 | 2000 |
Characterization and chromosome location of the gene GSTZ1 encoding the human Zeta class glutathione transferase and maleylacetoacetate isomerase AC Blackburn, E Woollatt, GR Sutherland, PG Board Cytogenetics and cell genetics 83 (1-2), 109-114, 1998 | 119 | 1998 |
Polymorphism-and species-dependent inactivation of glutathione transferase zeta by dichloroacetate HF Tzeng, AC Blackburn, PG Board, MW Anders Chemical research in toxicology 13 (4), 231-236, 2000 | 116 | 2000 |
Deficiency of glutathione transferase zeta causes oxidative stress and activation of antioxidant response pathways AC Blackburn, KI Matthaei, C Lim, MC Taylor, JY Cappello, JD Hayes, ... Molecular pharmacology 69 (2), 650-657, 2006 | 90 | 2006 |
Knockout and transgenic mice of Trp53: what have we learned about p53 in breast cancer? AC Blackburn, DJ Jerry Breast Cancer Research 4, 1-11, 2002 | 83 | 2002 |
Mice deficient in glutathione transferase zeta/maleylacetoacetate isomerase exhibit a range of pathological changes and elevated expression of alpha, mu, and pi class … CEL Lim, KI Matthaei, AC Blackburn, RP Davis, JE Dahlstrom, ME Koina, ... The American journal of pathology 165 (2), 679-693, 2004 | 76 | 2004 |
GSTZ1d: a new allele of glutathione transferase zeta and maleylacetoacetate isomerase AC Blackburn, M Coggan, HF Tzeng, H Lantum, G Polekhina, MW Parker, ... Pharmacogenetics and Genomics 11 (8), 671-678, 2001 | 74 | 2001 |
Targeting of two aspects of metabolism in breast cancer treatment BP Gang, PJ Dilda, PJ Hogg, AC Blackburn Cancer biology & therapy 15 (11), 1533-1541, 2014 | 61 | 2014 |
Loss of heterozygosity occurs via mitotic recombination in Trp53+/− mice and associates with mammary tumor susceptibility of the BALB/c strain AC Blackburn, SC McLary, R Naeem, J Luszcz, DW Stockton, ... Cancer research 64 (15), 5140-5147, 2004 | 61 | 2004 |
Leptin signals via TGFB1 to promote metastatic potential and stemness in breast cancer AK Mishra, CR Parish, ML Wong, J Licinio, AC Blackburn PLoS One 12 (5), e0178454, 2017 | 60 | 2017 |
Dichloroacetate prevents cisplatin-induced nephrotoxicity without compromising cisplatin anticancer properties R Galgamuwa, K Hardy, JE Dahlstrom, AC Blackburn, E Wium, M Rooke, ... Journal of the American Society of Nephrology 27 (11), 3331-3344, 2016 | 53 | 2016 |
Genetic mapping in mice identifies DMBT1 as a candidate modifier of mammary tumors and breast cancer risk AC Blackburn, LZ Hill, AL Roberts, J Wang, D Aud, J Jung, T Nikolcheva, ... The American journal of pathology 170 (6), 2030-2041, 2007 | 53 | 2007 |
Cancer progression as a sequence of atavistic reversions CH Lineweaver, KJ Bussey, AC Blackburn, PCW Davies BioEssays 43 (7), 2000305, 2021 | 48 | 2021 |