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Anastasia C. Murthy
Anastasia C. Murthy
Scientist II at Monte Rosa Tx
Adresse e-mail validée de monterosatx.com
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Année
Molecular interactions underlying liquid− liquid phase separation of the FUS low-complexity domain
AC Murthy, GL Dignon, Y Kan, GH Zerze, SH Parekh, J Mittal, NL Fawzi
Nature structural & molecular biology 26 (7), 637-648, 2019
4832019
SARS‐CoV‐2 nucleocapsid protein phase‐separates with RNA and with human hnRNPs
TM Perdikari, AC Murthy, VH Ryan, S Watters, MT Naik, NL Fawzi
The EMBO journal 39 (24), e106478, 2020
2042020
The (un) structural biology of biomolecular liquid-liquid phase separation using NMR spectroscopy
AC Murthy, NL Fawzi
Journal of Biological Chemistry 295 (8), 2375-2384, 2020
912020
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease
RJ Wheeler, HO Lee, I Poser, A Pal, T Doeleman, S Kishigami, S Kour, ...
872019
Molecular interactions contributing to FUS SYGQ LC-RGG phase separation and co-partitioning with RNA polymerase II heptads
AC Murthy, WS Tang, N Jovic, AM Janke, DH Seo, TM Perdikari, J Mittal, ...
Nature structural & molecular biology 28 (11), 923-935, 2021
712021
SARS-CoV-2 nucleocapsid protein undergoes liquid-liquid phase separation stimulated by RNA and partitions into phases of human ribonucleoproteins.
TM Perdikari, AC Murthy, VH Ryan, S Watters, MT Naik, NL Fawzi
BioRxiv, 2020
492020
N‐terminal acetylation modestly enhances phase separation and reduces aggregation of the low‐complexity domain of RNA‐binding protein fused in sarcoma
AS Bock, AC Murthy, WS Tang, N Jovic, F Shewmaker, J Mittal, NL Fawzi
Protein Science 30 (7), 1337-1349, 2021
302021
Reversible kinetic trapping of FUS biomolecular condensates
S Chatterjee, Y Kan, M Brzezinski, K Koynov, RM Regy, AC Murthy, ...
Advanced Science 9 (4), 2104247, 2022
282022
Fibril formation and ordering of disordered FUS LC driven by hydrophobic interactions
D Maltseva, S Chatterjee, CC Yu, M Brzezinski, Y Nagata, G Gonella, ...
Nature chemistry 15 (8), 1146-1154, 2023
132023
Incorporating NOE-derived distances in conformer generation of cyclic peptides with distance geometry
S Wang, K Krummenacher, GA Landrum, BD Sellers, P Di Lello, ...
Journal of Chemical Information and Modeling 62 (3), 472-485, 2022
102022
Small molecules for modulating protein driven liquid-liquid phase separation in treating neurodegenerative disease. bioRxiv. 2019; 721001
RJ Wheeler, HO Lee, I Poser, A Pal, T Doeleman, S Kishigami, S Kour, ...
Google Scholar][CrossRef][Green Version], 0
8
Molecular insights into the effect of alkanediols on FUS liquid-liquid phase separation
TM Perdikari, A Murthy, NL Fawzi
Biophysical Journal 122 (3), 484a, 2023
72023
An inquiry-based laboratory module to promote understanding of the scientific method and bacterial conjugation
MB Berkmen, AC Murthy, MP Broulidakis
Journal of Microbiology & Biology Education 15 (2), 321-322, 2014
62014
Small molecules for modulating protein driven liquid-liquid phase separation in neurodegenerative disease.
RJ Wheeler, H Lee, A Pal, A Murthy, I Poser, L Marrone, T Doeleman, ...
Molecular Biology of the Cell 28, 2017
32017
Interactions between FUS and the C-terminal Domain of Nup62 are Sufficient for their Co-phase Separation into Amorphous Assemblies
MS Kumar, KM Stallworth, AC Murthy, SM Lim, N Li, A Jain, JB Munro, ...
Journal of molecular biology 435 (6), 167972, 2023
22023
Sapun H Parekh, Jeetain Mittal, and Nicolas L Fawzi. Molecular 35 interactions underlying liquid-liquid phase separation of the FUS low-36 complexity domain
AC Murthy, GL Dignon, Y Kan, GH Zerze
Nature Structural & Molecular Biology 26 (7), 637-37, 34
234
Defining RNA oligonucleotides that reverse deleterious phase transitions of RNA-binding proteins with prion-like domains
L Guo, JR Mann, JC Mauna, KE Copley, H Wang, JD Rubien, HM Odeh, ...
bioRxiv, 2023.09. 04.555754, 2023
12023
EGFP insertional mutagenesis reveals multiple FXR2P fibrillar states with differing ribosome association in neurons
EE Stackpole, MR Akins, M Ivshina, AC Murthy, NL Fawzi, JR Fallon
Biology Open 8 (8), bio046383, 2019
12019
Intrinsically disordered regions and RNA binding domains contribute to protein enrichment in biomolecular condensates in Xenopus oocytes
LC O’Connell, V Johnson, AK Hutton, JP Otis, AC Murthy, MC Liang, ...
bioRxiv, 2023
2023
Characterization of ConE, the VirB4 Homolog of the Integrative and Conjugative Element ICEBs1 of Bacillus subtilis
AC Murthy, N Aleksanyan, GM Morton, HC Toyoda, M Kalashyan, S Chen, ...
Journal of Bacteriology 205 (6), e00033-23, 2023
2023
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