| Distinct profiles of functional discrimination among G proteins determine the actions of G protein–coupled receptors I Masuho, O Ostrovskaya, GM Kramer, CD Jones, K Xie, KA Martemyanov Science signaling 8 (405), ra123-ra123, 2015 | 224 | 2015 |
| Neuroprotective effect of paeoniflorin on cerebral ischemic rat by activating adenosine A1 receptor in a manner different from its classical agonists DZ Liu, KQ Xie, XQ Ji, Y Ye, CL Jiang, XZ Zhu British journal of pharmacology 146 (4), 604-611, 2005 | 167 | 2005 |
| Gβ5 recruits R7 RGS proteins to GIRK channels to regulate the timing of neuronal inhibitory signaling K Xie, KL Allen, S Kourrich, J Colón-Saez, MJ Thomas, K Wickman, ... Nature neuroscience 13 (6), 661-663, 2010 | 89 | 2010 |
| Retina-specific GTPase accelerator RGS11/Gβ5S/R9AP is a constitutive heterotrimer selectively targeted to mGluR6 in ON-bipolar neurons Y Cao, I Masuho, H Okawa, K Xie, J Asami, PJ Kammermeier, ... Journal of Neuroscience 29 (29), 9301-9313, 2009 | 89 | 2009 |
| Procyanidin dimer B2 [epicatechin-(4β-8)-epicatechin] suppresses the expression of cyclooxygenase-2 in endotoxin-treated monocytic cells W Zhang, H Liu, K Xie, L Yin, Y Li, CL Kwik-Uribe Biochemical and Biophysical Research Communications 345 (1), 508-515, 2006 | 88 | 2006 |
| RGS7/Gβ5/R7BP complex regulates synaptic plasticity and memory by modulating hippocampal GABABR-GIRK signaling. O Ostrovskaya, K Xie, M Ikuo, A Fajardo-Serrano, R Lujan, K Wickman, ... eLife 2014 (3), e02053, 2014 | 85 | 2014 |
| Orphan receptor GPR158 controls stress-induced depression LP Sutton, C Orlandi, C Song, WC Oh, BS Muntean, K Xie, A Filippini, ... Elife 7, e33273, 2018 | 65 | 2018 |
| Control of striatal signaling by g protein regulators K Xie, KA Martemyanov Frontiers in neuroanatomy 5, 49, 2011 | 64 | 2011 |
| Macromolecular Composition Dictates Receptor and G Protein Selectivity of Regulator of G Protein Signaling (RGS) 7 and 9-2 Protein Complexes in Living Cells I Masuho, K Xie, KA Martemyanov The Journal of Biological Chemistry 288, 25129-25142, 2013 | 59 | 2013 |
| The Complex of G Protein Regulator RGS9-2 and Gβ5 Controls Sensitization and Signaling Kinetics of Type 5 Adenylyl Cyclase in the Striatum K. Xie, I. Masuho, C. Brand, C. W. Dessauer, K. A SCIENCE SIGNALING 5 (239), ra63, 2012 | 51 | 2012 |
| Orphan Receptor GPR158 Is an Allosteric Modulator of RGS7 Catalytic Activity with an Essential Role in Dictating Its Expression and Localization in the Brain*♦ C Orlandi, K Xie, I Masuho, A Fajardo-Serrano, R Lujan, KA Martemyanov Journal of Biological Chemistry 290 (22), 13622-13639, 2015 | 47 | 2015 |
| Regulator of G-protein signaling 7 regulates reward behavior by controlling opioid signaling in the striatum LP Sutton, O Ostrovskaya, M Dao, K Xie, C Orlandi, R Smith, S Wee, ... Biological psychiatry 80 (3), 235-245, 2016 | 40 | 2016 |
| Paeoniflorin suppresses the expression of intercellular adhesion molecule‐1 (ICAM‐1) in endotoxin‐treated human monocytic cells L Jin, LM Zhang, KQ Xie, Y Ye, L Feng British Journal of Pharmacology 164 (2b), 694-703, 2011 | 35 | 2011 |
| NF1 is a direct G protein effector essential for opioid signaling to Ras in the striatum K Xie, LA Colgan, MT Dao, BS Muntean, LP Sutton, C Orlandi, SL Boye, ... Current Biology 26 (22), 2992-3003, 2016 | 34 | 2016 |
| Gβ5-RGS complexes are gatekeepers of hyperactivity involved in control of multiple neurotransmitter systems K Xie, S Ge, VE Collins, CL Haynes, KJ Renner, RL Meisel, R Lujan, ... Psychopharmacology 219, 823-834, 2012 | 34 | 2012 |
| Stable G protein-effector complexes in striatal neurons: mechanism of assembly and role in neurotransmitter signaling K Xie, I Masuho, CC Shih, Y Cao, K Sasaki, CWJ Lai, PL Han, H Ueda, ... Elife 4, e10451, 2015 | 31 | 2015 |
| Adenosine A1 receptor-mediated transactivation of the EGF receptor produces a neuroprotective effect on cortical neurons in vitro K Xie, L Zhang, Y Cao, J Zhu, L Feng Acta Pharmacologica Sinica 30 (7), 889-898, 2009 | 30 | 2009 |
| The enhancement of dopamine D1 receptor desensitization by adenosine A1 receptor activation Y Cao, KQ Xie, XZ Zhu European journal of pharmacology 562 (1-2), 34-38, 2007 | 27 | 2007 |
| Activation of adenosine A1 receptor modulates dopamine D1 receptor activity in stably cotransfected human embryonic kidney 293 cells Y Cao, WC Sun, L Jin, KQ Xie, XZ Zhu European journal of pharmacology 548 (1-3), 29-35, 2006 | 21 | 2006 |
| A conserved protein interaction interface on the type 5 G protein β subunit controls proteolytic stability and activity of R7 family regulator of G protein signaling proteins MY Porter, K Xie, E Pozharski, MR Koelle, KA Martemyanov Journal of biological chemistry 285 (52), 41100-41112, 2010 | 19 | 2010 |
Kirill MartemyanovProfessor, The Scripps Research InstituteAdresse e-mail validée de scripps.edu
