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Cyril RONCO
Cyril RONCO
PhD, HDR, Université Côte d'Azur - UMR7272CNRS / Membre de l'Institut Universitaire de France
Adresse e-mail validée de univ-cotedazur.fr
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Crystal structures of human cholinesterases in complex with huprine W and tacrine: elements of specificity for anti-Alzheimer's drugs targeting acetyl-and butyryl-cholinesterase
F Nachon, E Carletti, C Ronco, M Trovaslet, Y Nicolet, L Jean, PY Renard
Biochemical Journal 453 (3), 393-399, 2013
3942013
Compounds triggering ER stress exert anti-melanoma effects and overcome BRAF inhibitor resistance
M Cerezo, A Lehraiki, A Millet, F Rouaud, M Plaisant, E Jaune, T Botton, ...
Cancer cell 29 (6), 805-819, 2016
2362016
Metastatic melanoma: insights into the evolution of the treatments and future challenges
A Millet, AR Martin, C Ronco, S Rocchi, R Benhida
Medicinal research reviews 37 (1), 98-148, 2017
1122017
Human butyrylcholinesterase produced in insect cells: huprine‐based affinity purification and crystal structure
X Brazzolotto, M Wandhammer, C Ronco, M Trovaslet, L Jean, ...
The FEBS journal 279 (16), 2905-2916, 2012
1122012
ATM, ATR, CHK1, CHK2 and WEE1 inhibitors in cancer and cancer stem cells
C Ronco, AR Martin, L Demange, R Benhida
Medchemcomm 8 (2), 295-319, 2017
1012017
Synthesis and structure–activity relationship of Huprine derivatives as human acetylcholinesterase inhibitors
C Ronco, G Sorin, F Nachon, R Foucault, L Jean, A Romieu, PY Renard
Bioorganic & medicinal chemistry 17 (13), 4523-4536, 2009
582009
Synthesis and biological evaluation of 3-amino-1, 2, 4-triazole derivatives as potential anticancer compounds
O Grytsai, O Valiashko, M Penco-Campillo, M Dufies, A Hagege, ...
Bioorganic chemistry 104, 104271, 2020
562020
Controlling plasma stability of hydroxamic acids: A medchem toolbox
P Hermant, D Bosc, C Piveteau, R Gealageas, B Lam, C Ronco, ...
Journal of Medicinal Chemistry 60 (21), 9067-9089, 2017
482017
New huprine derivatives functionalized at position 9 as highly potent acetylcholinesterase inhibitors
C Ronco, R Foucault, E Gillon, P Bohn, F Nachon, L Jean, PY Renard
ChemMedChem 6 (5), 876-888, 2011
442011
A fluorescent immunochromatographic test using immunoliposomes for detecting microcystins and nodularins
N Khreich, P Lamourette, B Lagoutte, C Ronco, X Franck, C Créminon, ...
Analytical and bioanalytical chemistry 397 (5), 1733-1742, 2010
442010
New CXCR1/CXCR2 inhibitors represent an effective treatment for kidney or head and neck cancers sensitive or refractory to reference treatments
M Dufies, O Grytsai, C Ronco, O Camara, D Ambrosetti, A Hagege, ...
Theranostics 9 (18), 5332, 2019
432019
Huprine derivatives as sub‐nanomolar human acetylcholinesterase inhibitors: from rational design to validation by X‐ray crystallography
C Ronco, E Carletti, JP Colletier, M Weik, F Nachon, L Jean, PY Renard
ChemMedChem 7 (3), 400-405, 2012
392012
The GRP78/BiP inhibitor HA15 synergizes with mitotane action against adrenocortical carcinoma cells through convergent activation of ER stress pathways
C Ruggiero, M Doghman-Bouguerra, C Ronco, R Benhida, S Rocchi, ...
Molecular and cellular endocrinology 474, 57-64, 2018
352018
Structure–activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino] acetic acids, dual binders of human insulin-degrading enzyme
J Charton, M Gauriot, J Totobenazara, N Hennuyer, J Dumont, D Bosc, ...
European journal of medicinal chemistry 90, 547-567, 2015
312015
Discovery and Optimization of N-(4-(3-Aminophenyl)thiazol-2-yl)acetamide as a Novel Scaffold Active against Sensitive and Resistant Cancer Cells
A Millet, M Plaisant, C Ronco, M Cerezo, P Abbe, E Jaune, E Cavazza, ...
Journal of medicinal chemistry 59 (18), 8276-8292, 2016
272016
Reaction site-driven regioselective synthesis of AChE inhibitors
E Oueis, G Santoni, C Ronco, O Syzgantseva, V Tognetti, L Joubert, ...
Organic & biomolecular chemistry 12 (1), 156-161, 2014
262014
Improved synthetic pathway for the derivatization of huprine scaffold
C Ronco, L Jean, PY Renard
Tetrahedron 66 (37), 7399-7404, 2010
262010
Unified Azoline and Azole Syntheses by Optimized Aza‐Wittig Chemistry
P Loos, C Ronco, M Riedrich, HD Arndt
European Journal of Organic Chemistry 2013 (16), 3290-3315, 2013
252013
Recent advances in age-related macular degeneration therapies
M Fabre, L Mateo, D Lamaa, S Baillif, G Pagès, L Demange, C Ronco, ...
Molecules 27 (16), 5089, 2022
222022
Hypoxia inducible factor down-regulation, cancer and cancer stem cells (CSCs): ongoing success stories
AR Martin, C Ronco, L Demange, R Benhida
MedChemComm 8 (1), 21-52, 2017
222017
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