Sebastian Müller
Sebastian Müller
Senior Scientist (CR), Institut Curie, Paris/ INSERM
Verified email at - Homepage
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A novel small molecule that alters shelterin integrity and triggers a DNA-damage response at telomeres
R Rodriguez, S Müller, JA Yeoman, C Trentesaux, JF Riou, ...
Journal of the American Chemical Society 130 (47), 15758-15759, 2008
Small-molecule-mediated G-quadruplex isolation from human cells
S Müller, S Kumari, R Rodriguez, S Balasubramanian
Nature chemistry 2 (12), 1095-1098, 2010
Salinomycin kills cancer stem cells by sequestering iron in lysosomes
TT Mai, A Hamaï, A Hienzsch, T Cañeque, S Müller, J Wicinski, O Cabaud, ...
Nature Chemistry, 10.1038/nchem.2778, 2017
Pyridostatin analogues promote telomere dysfunction and long-term growth inhibition in human cancer cells
S Müller, DA Sanders, M Di Antonio, S Matsis, JF Riou, R Rodriguez, ...
Organic & biomolecular chemistry 10 (32), 6537-6546, 2012
G-quadruplex interacting small molecules and drugs: from bench toward bedside
S Müller, R Rodriguez
Expert review of clinical pharmacology 7 (5), 663-679, 2014
Histone H3 variants and their chaperones during development and disease: contributing to epigenetic control
D Filipescu, S Müller, G Almouzni
Annual review of cell and developmental biology 30, 615-646, 2014
Chromatin dynamics during the cell cycle at centromeres
S Müller, G Almouzni
Nature Reviews Genetics 18 (3), 192-208, 2017
Targeting the c-Kit Promoter G-quadruplexes with 6-Substituted Indenoisoquinolines
M Bejugam, M Gunaratnam, S Müller, DA Sanders, S Sewitz, ...
ACS medicinal chemistry letters 1 (7), 306-310, 2010
HJURP involvement in de novo CenH3CENP-A and CENP-C recruitment
H Tachiwana, S Müller, J Blümer, K Klare, A Musacchio, G Almouzni
Cell reports 11 (1), 22-32, 2015
Phosphorylation and DNA binding of HJURP determine its centromeric recruitment and function in CenH3CENP-A loading
S Müller, RM de Oca, N Lacoste, F Dingli, D Loew, G Almouzni
Cell reports 8 (1), 190-203, 2014
A network of players in H3 histone variant deposition and maintenance at centromeres
S Müller, G Almouzni
Biochimica et Biophysica Acta (BBA)-Gene Regulatory Mechanisms 1839 (3), 241-250, 2014
Patients with a non‐dysferlin Miyoshi myopathy have a novel membrane repair defect
JK Jaiswal, G Marlow, G Summerill, I Mahjneh, S Mueller, M Hill, K Miyake, ...
Traffic 8 (1), 77-88, 2007
Visualizing biologically active small molecules in cells using click chemistry
T Cañeque, S Müller, R Rodriguez
Nature Reviews Chemistry 2 (9), 202-215, 2018
The CENP-T/-W complex is a binding partner of the histone chaperone FACT
L Prendergast, S Müller, Y Liu, H Huang, F Dingli, D Loew, I Vassias, ...
Genes & development 30 (11), 1313-1326, 2016
Targeting DNA G‐Quadruplexes with Helical Small Molecules
S Müller, K Laxmi‐Reddy, PV Jena, B Baptiste, Z Dong, F Godde, T Ha, ...
ChemBioChem 15 (17), 2563-2570, 2014
PML-regulated mitochondrial metabolism enhances chemosensitivity in human ovarian cancers
G Gentric, Y Kieffer, V Mieulet, O Goundiam, C Bonneau, F Nemati, ...
Cell metabolism 29 (1), 156-173. e10, 2019
Controlled-folding of a small molecule modulates DNA G-quadruplex recognition
S Müller, GD Pantoş, R Rodriguez, S Balasubramanian
Chemical communications, 80-82, 2009
An iron hand over cancer stem cells
A Hamaï, T Cañeque, S Müller, TT Mai, A Hienzsch, C Ginestier, ...
Autophagy 13 (8), 1465-1466, 2017
Targeting cancer stem cells with small molecules
S Müller, T Cañeque, V Acevedo, R Rodriguez
Israel Journal of Chemistry 57 (3-4), 239-250, 2017
Quinolizinium as a new fluorescent lysosomotropic probe
RR Zacharioudakis E, Cañeque T, Custodio R, Müller S, Cuadro AM, Vaquero JJ
Bioorg Med Chem Lett 27 (2), 203-207, 2017
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