The oncogenic and clinical implications of lactate induced immunosuppression in the tumour microenvironment C Hayes, CL Donohoe, M Davern, NE Donlon Cancer letters 500, 75-86, 2021 | 101 | 2021 |
Cooperation between chemotherapy and immunotherapy in gastroesophageal cancers M Davern, J Lysaght Cancer letters 495, 89-99, 2020 | 45 | 2020 |
The tumour immune microenvironment in oesophageal cancer M Davern, NE Donlon, R Power, C Hayes, R King, MR Dunne, ... British Journal of Cancer 125 (4), 479-494, 2021 | 24 | 2021 |
CROSS versus FLOT regimens in esophageal and esophagogastric junction adenocarcinoma: a propensity-matched comparison NE Donlon, B Moran, A Kamilli, M Davern, A Sheppard, S King, ... Annals of Surgery 276 (5), 792-798, 2022 | 21 | 2022 |
FLOT-regimen chemotherapy and transthoracic en bloc resection for esophageal and junctional adenocarcinoma NE Donlon, A Kammili, R Roopnarinesingh, M Davern, R Power, S King, ... Annals of surgery 274 (5), 814-820, 2021 | 21 | 2021 |
Chemotherapy regimens induce inhibitory immune checkpoint protein expression on stem-like and senescent-like oesophageal adenocarcinoma cells M Davern, NE Donlon, A Sheppard, F O’Connell, C Hayes, A Bhardwaj, ... Translational Oncology 14 (6), 101062, 2021 | 17 | 2021 |
Linking circulating serum proteins with clinical outcomes in esophageal adenocarcinoma—an emerging role for chemokines NE Donlon, A Sheppard, M Davern, F O’Connell, JJ Phelan, R Power, ... Cancers 12 (11), 3356, 2020 | 17 | 2020 |
Characterisation of an isogenic model of cisplatin resistance in oesophageal adenocarcinoma cells AM Buckley, BAS Bibby, MR Dunne, SA Kennedy, MB Davern, ... Pharmaceuticals 12 (1), 33, 2019 | 14 | 2019 |
Acidosis significantly alters immune checkpoint expression profiles of T cells from oesophageal adenocarcinoma patients M Davern, NE Donlon, F O’Connell, C Gaughan, C O’Donovan, ... Cancer Immunology, Immunotherapy 72 (1), 55-71, 2023 | 13 | 2023 |
The impact of histone deacetylase inhibitors on immune cells and implications for cancer therapy B Moran, M Davern, JV Reynolds, NE Donlon, J Lysaght Cancer Letters 559, 216121, 2023 | 12 | 2023 |
Hypoxia and its impact on the tumour microenvironment of gastroesophageal cancers R King, C Hayes, CL Donohoe, MR Dunne, M Davern, NE Donlon World Journal of Gastrointestinal Oncology 13 (5), 312, 2021 | 12 | 2021 |
Radiation and immunotherapy in upper gastrointestinal cancers: the current state of play NE Donlon, R Power, C Hayes, M Davern, JV Reynolds, J Lysaght International Journal of Molecular Sciences 22 (3), 1071, 2021 | 12 | 2021 |
Real-time metabolic profiling of oesophageal tumours reveals an altered metabolic phenotype to different oxygen tensions and to treatment with Pyrazinib AM Buckley, MR Dunne, ME Morrissey, SA Kennedy, A Nolan, M Davern, ... Scientific reports 10 (1), 12105, 2020 | 11 | 2020 |
Fractalkine elicits chemotactic, phenotypic, and functional effects on CX3CR1+ CD27− NK cells in obesity-associated cancer E Mylod, AM Melo, NE Donlon, M Davern, A Bhardwaj, JV Reynolds, ... The Journal of Immunology 207 (4), 1200-1210, 2021 | 10 | 2021 |
The impact of esophageal oncological surgery on perioperative immune function; implications for adjuvant immune checkpoint inhibition NE Donlon, M Davern, AD Sheppard, F O’Connell, MR Dunne, C Hayes, ... Frontiers in Immunology 13, 823225, 2022 | 8 | 2022 |
The immune response to major gastrointestinal cancer surgery and potential implications for adjuvant immunotherapy NE Donlon, M Davern, C Hayes, R Power, AD Sheppard, CL Donohoe, ... Critical Reviews in Oncology/Hematology 175, 103729, 2022 | 7 | 2022 |
Impact of radiotherapy on the immune landscape in oesophageal adenocarcinoma NE Donlon, M Davern, F O’Connell, A Sheppard, A Heeran, A Bhardwaj, ... World Journal of Gastroenterology 28 (21), 2302, 2022 | 6 | 2022 |
Impact of COVID-19 on the diagnosis and surgical treatment of colorectal cancer: a national perspective NE Donlon, C Hayes, M Davern, JC Bolger, SC Irwin, WT Butt, ... Diseases of the Colon & Rectum 64 (11), 1305-1309, 2021 | 6 | 2021 |
Cooperation between chemotherapy and immune checkpoint blockade to enhance anti-tumour T cell immunity in oesophageal adenocarcinoma M Davern, NE Donlon, F O’Connell, AD Sheppard, C Hayes, R King, ... Translational Oncology 20, 101406, 2022 | 5 | 2022 |
PD-1 and TIGIT blockade differentially affect tumour cell survival under hypoxia and glucose deprived conditions in oesophageal adenocarcinoma; implications for overcoming … M Davern, MC Fitzgerald, CE Buckley, AB Heeran, NE Donlon, J McGrath, ... Translational oncology 19, 101381, 2022 | 5 | 2022 |