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Jacob Degner
Jacob Degner
AbbVie
Verified email at uchicago.edu - Homepage
Title
Cited by
Cited by
Year
Understanding mechanisms underlying human gene expression variation with RNA sequencing
JK Pickrell, JC Marioni, AA Pai, JF Degner, BE Engelhardt, E Nkadori, ...
Nature 464 (7289), 768-772, 2010
15252010
DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines
JT Bell, AA Pai, JK Pickrell, DJ Gaffney, R Pique-Regi, JF Degner, Y Gilad, ...
Genome biology 12 (1), R10, 2011
9882011
DNase I sensitivity QTLs are a major determinant of human expression variation
JF Degner, AA Pai, R Pique-Regi, JB Veyrieras, DJ Gaffney, JK Pickrell, ...
Nature 482 (7385), 390-394, 2012
7882012
Accurate inference of transcription factor binding from DNA sequence and chromatin accessibility data
R Pique-Regi, JF Degner, AA Pai, DJ Gaffney, Y Gilad, JK Pritchard
Genome research 21 (3), 447-455, 2011
6512011
Effect of read-mapping biases on detecting allele-specific expression from RNA-sequencing data
JF Degner, JC Marioni, AA Pai, JK Pickrell, E Nkadori, Y Gilad, ...
Bioinformatics 25 (24), 3207, 2009
6192009
Identification of genetic variants that affect histone modifications in human cells
G McVicker, B Van De Geijn, JF Degner, CE Cain, NE Banovich, A Raj, ...
Science 342 (6159), 747-749, 2013
5072013
Are drug targets with genetic support twice as likely to be approved? Revised estimates of the impact of genetic support for drug mechanisms on the probability of drug approval
EA King, JW Davis, JF Degner
PLoS genetics 15 (12), e1008489, 2019
4412019
The Burmese python genome reveals the molecular basis for extreme adaptation in snakes
TA Castoe, APJ De Koning, KT Hall, DC Card, DR Schield, MK Fujita, ...
Proceedings of the National Academy of Sciences 110 (51), 20645-20650, 2013
3112013
Methylation QTLs are associated with coordinated changes in transcription factor binding, histone modifications, and gene expression levels
NE Banovich, X Lan, G McVicker, B Van de Geijn, JF Degner, JD Blischak, ...
PLoS genetics 10 (9), e1004663, 2014
3012014
Dissecting the regulatory architecture of gene expression QTLs
DJ Gaffney, JB Veyrieras, JF Degner, R Pique-Regi, AA Pai, GE Crawford, ...
Genome biology 13, 1-15, 2012
2422012
The contribution of RNA decay quantitative trait loci to inter-individual variation in steady-state gene expression levels
AA Pai, CE Cain, O Mizrahi-Man, S De Leon, N Lewellen, JB Veyrieras, ...
Public Library of Science 8 (10), e1003000, 2012
1182012
Metabolic fright responses of different-sized largemouth bass (Micropterus salmoides) to two avian predators show variations in nonlethal energetic costs
SJ Cooke, J Steinmetz, JF Degner, EC Grant, DP Philipp
Canadian Journal of Zoology 81 (4), 699-709, 2003
872003
Promoter shape varies across populations and affects promoter evolution and expression noise
IE Schor, JF Degner, D Harnett, E Cannavò, FP Casale, H Shim, ...
Nature genetics 49 (4), 550-558, 2017
722017
Identification of HLA-DRB1 association to adalimumab immunogenicity
M Liu, J Degner, JW Davis, KB Idler, A Nader, NM Mostafa, JF Waring
PLoS One 13 (4), e0195325, 2018
692018
Genetic variants regulating expression levels and isoform diversity during embryogenesis
E Cannavò, N Koelling, D Harnett, D Garfield, FP Casale, L Ciglar, ...
Nature 541 (7637), 402-406, 2017
602017
Population genetics and conservation of the threatened southeastern beach mouse (Peromyscus polionotus niveiventris): subspecies and evolutionary units
JF Degner, IJ Stout, JD Roth, CL Parkinson
Conservation Genetics 8, 1441-1452, 2007
472007
Lineage-resolved enhancer and promoter usage during a time course of embryogenesis
JP Reddington, DA Garfield, OM Sigalova, AK Calviello, ...
Developmental cell 55 (5), 648-664. e9, 2020
462020
Population pharmacokinetics of elagolix in healthy women and women with endometriosis
I Winzenborg, A Nader, AR Polepally, M Liu, J Degner, CE Klein, ...
Clinical pharmacokinetics 57, 1295-1306, 2018
262018
Fat frogs, mobile genes: unexpected phylogeographic patterns for the ornate chorus frog (Pseudacris ornata)
JF Degner, DM Silva, TD Hether, JM Daza, EA Hoffman
Molecular Ecology 19 (12), 2501-2515, 2010
262010
A genetic variant in the BCL2 gene associates with adalimumab response in hidradenitis suppurativa clinical trials and regulates expression of BCL2
M Liu, J Degner, RW Georgantas, A Nader, NM Mostafa, HD Teixeira, ...
Journal of investigative dermatology 140 (3), 574-582. e2, 2020
202020
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