| ERK and p38 MAPK-activated protein kinases: a family of protein kinases with diverse biological functions PP Roux, J Blenis Microbiology and molecular biology reviews 68 (2), 320-344, 2004 | 2765 | 2004 |
| Activation and function of the MAPKs and their substrates, the MAPK-activated protein kinases M Cargnello, PP Roux Microbiology and molecular biology reviews 75 (1), 50-83, 2011 | 2188 | 2011 |
| Tuberous sclerosis complex gene products, Tuberin and Hamartin, control mTOR signaling by acting as a GTPase-activating protein complex toward Rheb AR Tee, BD Manning, PP Roux, LC Cantley, J Blenis Current biology 13 (15), 1259-1268, 2003 | 1268 | 2003 |
| Tumor-promoting phorbol esters and activated Ras inactivate the tuberous sclerosis tumor suppressor complex via p90 ribosomal S6 kinase PP Roux, BA Ballif, R Anjum, SP Gygi, J Blenis Proceedings of the National Academy of Sciences 101 (37), 13489-13494, 2004 | 854 | 2004 |
| Rapamycin differentially inhibits S6Ks and 4E-BP1 to mediate cell-type-specific repression of mRNA translation AY Choo, SO Yoon, SG Kim, PP Roux, J Blenis Proceedings of the National Academy of Sciences 105 (45), 17414-17419, 2008 | 801 | 2008 |
| Neurotrophin signaling through the p75 neurotrophin receptor PP Roux, PA Barker Progress in neurobiology 67 (3), 203-233, 2002 | 801 | 2002 |
| RAS/ERK signaling promotes site-specific ribosomal protein S6 phosphorylation via RSK and stimulates cap-dependent translation PP Roux, D Shahbazian, H Vu, MK Holz, MS Cohen, J Taunton, ... Journal of Biological Chemistry 282 (19), 14056-14064, 2007 | 693 | 2007 |
| The mTOR/PI3K and MAPK pathways converge on eIF4B to control its phosphorylation and activity D Shahbazian, PP Roux, V Mieulet, MS Cohen, B Raught, J Taunton, ... The EMBO journal 25 (12), 2781-2791, 2006 | 545 | 2006 |
| mTORC1-activated S6K1 phosphorylates Rictor on threonine 1135 and regulates mTORC2 signaling LA Julien, A Carriere, J Moreau, PP Roux Molecular and cellular biology 30 (4), 908-921, 2010 | 430 | 2010 |
| NRAGE, a novel MAGE protein, interacts with the p75 neurotrophin receptor and facilitates nerve growth factor–dependent apoptosis AH Salehi, PP Roux, CJ Kubu, C Zeindler, A Bhakar, LL Tannis, JM Verdi, ... Neuron 27 (2), 279-288, 2000 | 360 | 2000 |
| Oncogenic MAPK signaling stimulates mTORC1 activity by promoting RSK-mediated raptor phosphorylation A Carrière, M Cargnello, LA Julien, H Gao, É Bonneil, P Thibault, ... Current biology 18 (17), 1269-1277, 2008 | 343 | 2008 |
| Regulation and function of the RSK family of protein kinases Y Romeo, X Zhang, PP Roux Biochemical Journal 441 (2), 553-569, 2012 | 310 | 2012 |
| mTORC2 can associate with ribosomes to promote cotranslational phosphorylation and stability of nascent Akt polypeptide WJ Oh, C Wu, SJ Kim, V Facchinetti, LA Julien, M Finlan, PP Roux, B Su, ... The EMBO journal 29 (23), 3939-3951, 2010 | 302 | 2010 |
| p75 neurotrophin receptor expression is induced in apoptotic neurons after seizure PP Roux, MA Colicos, PA Barker, TE Kennedy Journal of neuroscience 19 (16), 6887-6896, 1999 | 264 | 1999 |
| A comprehensive map of the mTOR signaling network E Caron, S Ghosh, Y Matsuoka, D Ashton‐Beaucage, M Therrien, ... Molecular systems biology 6 (1), 453, 2010 | 255 | 2010 |
| Quantitative phosphorylation profiling of the ERK/p90 ribosomal S6 kinase-signaling cassette and its targets, the tuberous sclerosis tumor suppressors BA Ballif, PP Roux, SA Gerber, JP MacKeigan, J Blenis, SP Gygi Proceedings of the National Academy of Sciences 102 (3), 667-672, 2005 | 250 | 2005 |
| ERK1/2 phosphorylate Raptor to promote Ras-dependent activation of mTOR complex 1 (mTORC1) A Carriere, Y Romeo, HA Acosta-Jaquez, J Moreau, E Bonneil, P Thibault, ... Journal of Biological Chemistry 286 (1), 567-577, 2011 | 248 | 2011 |
| Transmembrane receptor DCC associates with protein synthesis machinery and regulates translation J Tcherkezian, PA Brittis, F Thomas, PP Roux, JG Flanagan Cell 141 (4), 632-644, 2010 | 244 | 2010 |
| Phosphorylation of p90 ribosomal S6 kinase (RSK) regulates extracellular signal-regulated kinase docking and RSK activity PP Roux, SA Richards, J Blenis Molecular and cellular biology 23 (14), 4796-4804, 2003 | 216 | 2003 |
| The RSK factors of activating the Ras/MAPK signaling cascade A Carriere, H Ray, J Blenis, PP Roux Front Biosci 13 (10), 4258-4275, 2008 | 211 | 2008 |
John BlenisProfessor of Pharmacology, Weill Cornell MedicineVerified email at med.cornell.edu
