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Jean-Pierre Brion
Jean-Pierre Brion
Adresse e-mail validée de ulb.ac.be
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Glycogen synthase kinase-3 induces Alzheimer's disease-like phosphorylation of tau: generation of paired helical filament epitopes and neuronal localisation of the kinase
DP Hanger, K Hughes, JR Woodgett, JP Brion, BH Anderton
Neuroscience letters 147 (1), 58-62, 1992
9321992
MISE EN ÉVIDENCE IMMUNOLOGIQUE DE LA PROTEINE TAU AU NIVEAU DES LESIONS DE DEGENERESCENCE NEUROFIBRILLAIRE DE LA MALADIE D‘ALZHEIMER
JP BRION, H Passareiro, J NUNEZ, J Jacqueline FLAMENT-DURAND
Archives de Biologie 95, 229-235, 1985
457*1985
Alzheimer's disease-like tau neuropathology leads to memory deficits and loss of functional synapses in a novel mutated tau transgenic mouse without any motor deficits
K Schindowski, A Bretteville, K Leroy, S Bégard, JP Brion, M Hamdane, ...
The American journal of pathology 169 (2), 599-616, 2006
4362006
Increased level of active GSK‐3β in Alzheimer’s disease and accumulation in argyrophilic grains and in neurones at different stages of neurofibrillary degeneration
K Leroy, Z Yilmaz, JP Brion
Neuropathology and applied neurobiology 33 (1), 43-55, 2007
4252007
What is the evidence that tau pathology spreads through prion-like propagation?
A Mudher, M Colin, S Dujardin, M Medina, I Dewachter, SM Alavi Naini, ...
Acta neuropathologica communications 5, 1-20, 2017
3282017
Neurofibrillary tangles of Alzheimer's disease: an immunohistochemical study.
JP Brion, AM Couck, E Passareiro, J Flament-Durand
Journal of submicroscopic cytology 17 (1), 89-96, 1985
3261985
PART is part of Alzheimer disease
C Duyckaerts, H Braak, JP Brion, L Buée, K Del Tredici, M Goedert, ...
Acta neuropathologica 129, 749-756, 2015
2982015
Developmental expression and localization of glycogen synthase kinase-3β in rat brain
K Leroy, JP Brion
Journal of chemical neuroanatomy 16 (4), 279-293, 1999
2831999
Mutations in tau reduce its microtubule binding properties in intact cells and affect its phosphorylation
R Dayanandan, M Van Slegtenhorst, TGA Mack, L Ko, SH Yen, K Leroy, ...
FEBS letters 446 (2-3), 228-232, 1999
2581999
Transgenic expression of the shortest human tau affects its compartmentalization and its phosphorylation as in the pretangle stage of Alzheimer's disease
JP Brion, G Tremp, JN Octave
The American journal of pathology 154 (1), 255-270, 1999
2551999
Clusterin regulates β-amyloid toxicity via Dickkopf-1-driven induction of the wnt–PCP–JNK pathway
R Killick, EM Ribe, R Al-Shawi, B Malik, C Hooper, C Fernandes, ...
Molecular psychiatry 19 (1), 88-98, 2014
2542014
Neurofibrillary tangles and Alzheimer’s disease
JP Brion
European neurology 40 (3), 130-140, 1998
2481998
Developmental Changes in τ Phosphorylation: Fetal τ Is Transiently Phosphorylated in a Manner Similar to Paired Helical Filament‐τ Characteristic of Alzheimer's Disease
JP Brion, C Smith, AM Couck, JM Gallo, BH Anderton
Journal of neurochemistry 61 (6), 2071-2080, 1993
2441993
Tyrosine 394 is phosphorylated in Alzheimer's paired helical filament tau and in fetal tau with c-Abl as the candidate tyrosine kinase
P Derkinderen, TME Scales, DP Hanger, KY Leung, HL Byers, MA Ward, ...
Journal of Neuroscience 25 (28), 6584-6593, 2005
2292005
The active form of glycogen synthase kinase-3β is associated with granulovacuolar degeneration in neurons in Alzheimer's disease
K Leroy, A Boutajangout, M Authelet, JR Woodgett, BH Anderton, JP Brion
Acta neuropathologica 103, 91-99, 2002
2272002
Hallmarks of Alzheimer’s disease in stem-cell-derived human neurons transplanted into mouse brain
I Espuny-Camacho, AM Arranz, M Fiers, A Snellinx, K Ando, S Munck, ...
Neuron 93 (5), 1066-1081. e8, 2017
2242017
Reduction of acetylated α-tubulin immunoreactivity in neurofibrillary tangle-bearing neurons in Alzheimer's disease
B Hempen, JP Brion
Journal of Neuropathology & Experimental Neurology 55 (9), 964-972, 1996
2111996
Abnormalities of Wnt signalling in schizophrenia–evidence for neurodevelopmental abnormality
D Cotter, R Kerwin, S Al-Sarraji, JP Brion, A Chadwich, S Lovestone, ...
Neuroreport 9 (7), 1379-1383, 1998
2091998
Lithium reduces tau phosphorylation: effects in living cells and in neurons at therapeutic concentrations
S Lovestone, DR Davis, MT Webster, S Kaech, JP Brion, A Matus, ...
Biological psychiatry 45 (8), 995-1003, 1999
1941999
Tau in Alzheimer neurofibrillary tangles. N- and C-terminal regions are differentially associated with paired helical filaments and the location of a putative abnormal …
JP Brion, DP Hanger, MT Bruce, AM Couck, J Flament-Durand, ...
Biochemical journal 273 (1), 127-133, 1991
1821991
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