A tale of two Paks LE Arias‐Romero, J Chernoff Biology of the Cell 100 (2), 97-108, 2008 | 409 | 2008 |
A Rac–Pak signaling pathway is essential for ErbB2-mediated transformation of human breast epithelial cancer cells LE Arias-Romero, O Villamar-Cruz, A Pacheco, R Kosoff, M Huang, ... Oncogene 29 (43), 5839-5849, 2010 | 119 | 2010 |
Activation of Src by protein tyrosine phosphatase 1B Is required for ErbB2 transformation of human breast epithelial cells LE Arias-Romero, S Saha, O Villamar-Cruz, SC Yip, SP Ethier, ZY Zhang, ... Cancer research 69 (11), 4582-4588, 2009 | 114 | 2009 |
Targeting Cdc42 in cancer LE Arias-Romero, J Chernoff Expert opinion on therapeutic targets 17 (11), 1263-1273, 2013 | 109 | 2013 |
Pak1 kinase links ErbB2 to β-catenin in transformation of breast epithelial cells LE Arias-Romero, O Villamar-Cruz, M Huang, KP Hoeflich, J Chernoff Cancer research 73 (12), 3671-3682, 2013 | 96 | 2013 |
Interaction with LC8 is required for Pak1 nuclear import and is indispensable for zebrafish development CM Lightcap, G Kari, LE Arias-Romero, J Chernoff, U Rodeck, ... PloS one 4 (6), e6025, 2009 | 62 | 2009 |
Lack of STAT6 attenuates inflammation and drives protection against early steps of colitis-associated colon cancer SA Leon-Cabrera, E Molina-Guzman, YG Delgado-Ramirez, ... Cancer immunology research 5 (5), 385-396, 2017 | 50 | 2017 |
L10 ribosomal protein from Entamoeba histolytica share structural and functional homologies with QM/Jif-1: proteins with extraribosomal functions R Chávez-Rios, LE Arias-Romero, M de Jesús Almaraz-Barrera, ... Molecular and biochemical parasitology 127 (2), 151-160, 2003 | 42 | 2003 |
p21-activated kinases in Erbb2-positive breast cancer: A new therapeutic target? LE Arias-Romero, J Chernoff Small GTPases 1 (2), 5839-5849, 2010 | 40 | 2010 |
p21 Activated kinase 1: Nuclear activity and its role during DNA damage repair EDL Pérez-Yépez, HI Saldívar-Cerón, O Villamar-Cruz, ... DNA repair 65, 42-46, 2018 | 39 | 2018 |
Early and partial reduction in CD4+ Foxp3+ regulatory T cells during colitis-associated colon cancer induces CD4+ and CD8+ T cell activation inhibiting tumorigenesis JE Olguín, I Medina-Andrade, E Molina, A Vázquez, ... Journal of Cancer 9 (2), 239, 2018 | 37 | 2018 |
Helminth‐derived molecules inhibit colitis‐associated colon cancer development through NF‐κB and STAT3 regulation BE Callejas, MG Mendoza‐Rodríguez, O Villamar‐Cruz, ... International journal of cancer 145 (11), 3126-3139, 2019 | 35 | 2019 |
H-ras inhibits the hippo pathway by promoting Mst1/Mst2 heterodimerization SJ Rawat, D Araiza-Olivera, LE Arias-Romero, O Villamar-Cruz, ... Current Biology 26 (12), 1556-1563, 2016 | 35 | 2016 |
Recent advances in PTP1B signaling in metabolism and cancer O Villamar-Cruz, MA Loza-Mejía, LE Arias-Romero, I Camacho-Arroyo Bioscience Reports 41 (11), BSR20211994, 2021 | 34 | 2021 |
EhPAK2, a novel p21-activated kinase, is required for collagen invasion and capping in Entamoeba histolytica LE Arias-Romero, M de Jesús Almáraz-Barrera, JD Díaz-Valencia, ... Molecular and biochemical parasitology 149 (1), 17-26, 2006 | 34 | 2006 |
Anti-inflammatory and antitumor activity of a triple therapy for a colitis-related colorectal cancer G Figueroa-González, V García-Castillo, J Coronel-Hernández, ... Journal of Cancer 7 (12), 1632, 2016 | 24 | 2016 |
IFI27/ISG12 downregulates estrogen receptor α transactivation by facilitating its interaction with CRM1/XPO1 in breast cancer cells MG Cervantes-Badillo, A Paredes-Villa, V Gómez-Romero, ... Frontiers in endocrinology 11, 568375, 2020 | 21 | 2020 |
EhGEF2, a Dbl-RhoGEF from Entamoeba histolytica has atypical biochemical properties and participates in essential cellular processes CHG De la Rosa, LE Arias-Romero, M de Jesús Almaraz-Barrera, ... Molecular and biochemical parasitology 151 (1), 70-80, 2007 | 21 | 2007 |
EhGEF3, a novel Dbl family member, regulates EhRacA activation during chemotaxis and capping in Entamoeba histolytica LE Arias‐Romero, CHG de la Rosa, MJ Almaráz‐Barrera, ... Cell Motility and the Cytoskeleton 64 (5), 390-404, 2007 | 20 | 2007 |
Reduced PAK1 activity sensitizes FA/BRCA-proficient breast cancer cells to PARP inhibition O Villamar-Cruz, TY Prudnikova, D Araiza-Olivera, C Perez-Plasencia, ... Oncotarget, 2016 | 14 | 2016 |