Héléna A. Gaspar
Héléna A. Gaspar
Senior Chemoinformatics Data Scientist, BenevolentAI; Visiting Scientist, King's College London
Adresse e-mail validée de kcl.ac.uk
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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression
NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui, ...
Nature genetics 50 (5), 668-681, 2018
12702018
Genome-wide association study identifies 30 loci associated with bipolar disorder
EA Stahl, G Breen, AJ Forstner, A McQuillin, S Ripke, V Trubetskoy, ...
Nature genetics 51 (5), 793-803, 2019
6062019
Genetic identification of brain cell types underlying schizophrenia
NG Skene, J Bryois, TE Bakken, G Breen, JJ Crowley, HA Gaspar, ...
Nature genetics 50 (6), 825-833, 2018
2802018
Significant locus and metabolic genetic correlations revealed in genome-wide association study of anorexia nervosa
L Duncan, Z Yilmaz, H Gaspar, R Walters, J Goldstein, V Anttila, ...
American journal of psychiatry 174 (9), 850-858, 2017
2772017
Genome-wide association study identifies eight risk loci and implicates metabo-psychiatric origins for anorexia nervosa
HJ Watson, Z Yilmaz, LM Thornton, C Hübel, JRI Coleman, HA Gaspar, ...
Nature genetics 51 (8), 1207-1214, 2019
2572019
Genomic dissection of bipolar disorder and schizophrenia, including 28 subphenotypes
DM Ruderfer, S Ripke, A McQuillin, J Boocock, EA Stahl, JMW Pavlides, ...
Cell 173 (7), 1705-1715. e16, 2018
2272018
Genomic relationships, novel loci, and pleiotropic mechanisms across eight psychiatric disorders
PH Lee, V Anttila, H Won, YCA Feng, J Rosenthal, Z Zhu, EM Tucker-Drob, ...
Cell 179 (7), 1469-1482. e11, 2019
1432019
Comparative genetic architectures of schizophrenia in East Asian and European populations
M Lam, CY Chen, Z Li, AR Martin, J Bryois, X Ma, H Gaspar, M Ikeda, ...
Nature genetics 51 (12), 1670-1678, 2019
1352019
Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium.(2018). Genome-wide association analyses identify 44 risk variants and refine the genetic …
NR Wray, S Ripke, M Mattheisen, M Trzaskowski, EM Byrne, A Abdellaoui
Nature Genetics 50 (5), 668-681, 0
115
Generative topographic mapping (GTM): universal tool for data visualization, structure‐activity modeling and dataset comparison
N Kireeva, II Baskin, HA Gaspar, D Horvath, G Marcou, A Varnek
Molecular Informatics 31 (3‐4), 301-312, 2012
1102012
Translating genome-wide association findings into new therapeutics for psychiatry
G Breen, Q Li, BL Roth, P O'Donnell, M Didriksen, R Dolmetsch, ...
Nature neuroscience 19 (11), 1392-1396, 2016
1042016
Chemical data visualization and analysis with incremental generative topographic mapping: big data challenge
HA Gaspar, II Baskin, G Marcou, D Horvath, A Varnek
Journal of chemical information and modeling 55 (1), 84-94, 2015
802015
Bipolar Disorder Working Group of the Psychiatric Genomics Consortium. Genome-wide association study identifies 30 loci associated with bipolar disorder
EA Stahl, G Breen, AJ Forstner, A McQuillin, S Ripke, V Trubetskoy, A Reif
Nat Genet 51 (5), 793-803, 2019
722019
A major role for common genetic variation in anxiety disorders
KL Purves, JRI Coleman, SM Meier, C Rayner, KAS Davis, R Cheesman, ...
Molecular psychiatry 25 (12), 3292-3303, 2020
692020
Generative topographic mapping-based classification models and their applicability domain: application to the biopharmaceutics drug disposition classification system (BDDCS)
HA Gaspar, G Marcou, D Horvath, A Arault, S Lozano, P Vayer, A Varnek
Journal of chemical information and modeling 53 (12), 3318-3325, 2013
642013
GTM‐Based QSAR Models and Their Applicability Domains
HA Gaspar, II Baskin, G Marcou, D Horvath, A Varnek
Molecular informatics 34 (6‐7), 348-356, 2015
612015
A genome-wide association study for extremely high intelligence
D Zabaneh, E Krapohl, HA Gaspar, C Curtis, SH Lee, H Patel, ...
Molecular psychiatry 23 (5), 1226-1232, 2018
542018
Does childhood trauma moderate polygenic risk for depression? A meta-analysis of 5765 subjects from the psychiatric genomics consortium
WJ Peyrot, S Van der Auwera, Y Milaneschi, CV Dolan, PAF Madden, ...
Biological psychiatry 84 (2), 138-147, 2018
512018
Mappability of drug-like space: towards a polypharmacologically competent map of drug-relevant compounds
P Sidorov, H Gaspar, G Marcou, A Varnek, D Horvath
Journal of computer-aided molecular design 29 (12), 1087-1108, 2015
462015
Genomics of body fat percentage may contribute to sex bias in anorexia nervosa
C Hübel, HA Gaspar, JRI Coleman, H Finucane, KL Purves, ...
American Journal of Medical Genetics Part B: Neuropsychiatric Genetics 180 …, 2019
452019
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