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Bernadette Scutellà
Bernadette Scutellà
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How vial geometry variability influences heat transfer and product temperature during freeze-drying
B Scutella, S Passot, E Bourlés, F Fonseca, IC Tréléa
Journal of Pharmaceutical Sciences 106 (3), 770-778, 2017
612017
3D mathematical modelling to understand atypical heat transfer observed in vial freeze-drying
B Scutellà, A Plana-Fattori, S Passot, E Bourlès, F Fonseca, D Flick, ...
Applied thermal engineering 126, 226-236, 2017
582017
Determination of the dried product resistance variability and its influence on the product temperature in pharmaceutical freeze-drying
B Scutella, IC Trelea, E Bourlés, F Fonseca, S Passot
European Journal of Pharmaceutics and Biopharmaceutics 128, 379-388, 2018
282018
Towards in silico process modeling for vaccines
AG Cardillo, MM Castellanos, B Desailly, S Dessoy, M Mariti, ...
Trends in biotechnology 39 (11), 1120-1130, 2021
182021
In-line monitoring of the freeze-drying process by means of heat flux sensors
C Moino, E Bourles, R Pisano, B Scutella
Industrial & Engineering Chemistry Research 60 (26), 9637-9645, 2021
152021
Scale-up of freeze-drying cycles, the use of process analytical technology (PAT), and statistical analysis
E Bourlès, G de Lannoy, B Scutellà, F Fonseca, IC Trelea, S Passot
Lyophilization of Pharmaceuticals and Biologicals: New Technologies and …, 2019
142019
Effect of freeze dryer design on heat transfer variability investigated using a 3D mathematical model
B Scutellà, E Bourlès, A Plana-Fattori, F Fonseca, D Flick, IC Trelea, ...
Journal of Pharmaceutical Sciences 107 (8), 2098-2106, 2018
82018
Development of freeze-drying cycle via design space approach: a case study on vaccines
B Scutella, E Bourles
Pharmaceutical Development and Technology 25 (10), 1302-1313, 2020
72020
Use of a multi-vial mathematical model to design freeze-drying cycles for pharmaceuticals at known risk of failure
B Scutellà, IC Trelea, E Bourlés, F Fonseca, S Passot
IDS 2018. 21st International Drying Symposium Proceedings, 315-322, 2018
62018
Heat transfer during freeze-drying using a high-throughput vial system in view of process scale-up to serum vials
JP Buceta, IC Tréléa, B Scutellà, E Bourlés, F Fonseca, S Passot
Journal of Pharmaceutical Sciences 110 (3), 1323-1336, 2021
52021
Analysis of the Shear Stresses in a Filling Line of Parenteral Products: The Role of Tubing
C Moino, B Scutellà, M Bellini, E Bourlès, G Boccardo, R Pisano
Processes 11 (3), 833, 2023
42023
Surface treatment of glass vials for lyophilization: implications for vacuum-induced surface freezing
F Regis, A Arsiccio, E Bourlès, B Scutellà, R Pisano
Pharmaceutics 13 (11), 1766, 2021
42021
Use of 3D mathematical modelling to understand the heat transfer mechanisms during freeze-drying using high-throughput vials
JP Buceta, S Passot, B Scutellà, E Bourlés, F Fonseca, IC Trelea
Applied Thermal Engineering 207, 118099, 2022
32022
Analysis of the Shear Stresses in a Filling Line of Parenteral Products: The Role of Fittings
C Moino, B Scutellà, M Bellini, E Bourlès, G Boccardo, R Pisano
Processes 11 (6), 1797, 2023
22023
Freeze-drying of vaccines: Contribution of mathematical modelling for assessing product heterogeneity and scale-up risks
B Scutella
Université Paris Saclay (COmUE), 2017
22017
Can the desorption kinetics explain the residual moisture content heterogeneity observed in pharmaceuticals freeze-drying process?
B Scutella, E Bourlés, C Tordjman, F Fonseca, Y Mayeresse, IC Trelea, ...
6. European Drying Conference: EuroDrying 2017, np, 2017
22017
Analysis of the shear stresses in a filling line of parenteral products: The role of sterilizing filters
C Moino, E Agostini, A Albano, M Bellini, E Bourlès, B Scutellà, ...
Separation and Purification Technology 344, 127248, 2024
2024
Scale-down modeling of the filling process for vaccine production
C Moino, B Scutellà, M Bellini, E Bourlès, G Boccardo, R Pisano
Abstracts ECCE/ECAB 2023, 2023
2023
Scale-Down Modeling of the Filling Process for Protein-Based Parenteral Drug Products
C Moino, B Scutella, M Bellini, E Bourles, G Boccardo, R Pisano
2023 AIChE Annual Meeting proceedings, 1-6, 2023
2023
Analysis of the shear stresses in a filling line of parenteral products
C Moino, B Scutellà, A Albano, M Bellini, E Bourlès, G Boccardo, ...
Titolo volume non avvalorato, 2023
2023
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