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John F. Brothers II
John F. Brothers II
Bioinformatics Scientist
Verified email at immuneering.com - Homepage
Title
Cited by
Cited by
Year
Host response to the lung microbiome in chronic obstructive Pulmonary Disease
MA Sze, PA Dimitriu, M Suzuki, JE McDonough, JD Campbell, JF Brothers, ...
American journal of respiratory and critical care medicine 192 (4), 438-445, 2015
2742015
Integrated Genomics Reveals Convergent Transcriptomic Networks Underlying COPD and IPF
RL Kusko, JF Brothers II, J Tedrow, K Pandit, L Huleihel, C Perdomo, ...
Am J Respir Crit Care Med, 2016
1172016
Gene activation of SMN by selective disruption of lncRNA-mediated recruitment of PRC2 for the treatment of spinal muscular atrophy
CJ Woo, VK Maier, R Davey, J Brennan, G Li, J Brothers, B Schwartz, ...
Proceedings of the National Academy of Sciences 114 (8), E1509-E1518, 2017
882017
Genetic variation and antioxidant response gene expression in the bronchial airway epithelium of smokers at risk for lung cancer
X Wang, BN Chorley, GS Pittman, SR Kleeberger, J Brothers II, G Liu, ...
PLoS One 5 (8), e11934, 2010
682010
Bridging the clinical gaps: genetic, epigenetic and transcriptomic biomarkers for the early detection of lung cancer in the post-National Lung Screening Trial era
JF Brothers, K Hijazi, C Mascaux, RA El-Zein, MR Spitz, A Spira
BMC medicine 11 (1), 168, 2013
672013
Transcriptomic studies of the airway field of injury associated with smoking-related lung disease
AC Gower, K Steiling, JF Brothers, ME Lenburg, A Spira
Proceedings of the American Thoracic Society 8 (2), 173-179, 2011
612011
Elevated neutrophil gelatinase-associated lipocalin contributes to erlotinib resistance in non-small cell lung cancer
K Krysan, X Cui, BK Gardner, KL Reckamp, X Wang, L Hong, TC Walser, ...
Am J Transl Res 5 (5), 481-496, 2013
202013
Linking polymorphic p53 response elements with gene expression in airway epithelial cells of smokers and cancer risk
X Wang, GS Pittman, OJ Bandele, JJ Bischof, G Liu, JF Brothers II, A Spira, ...
Human genetics 133 (12), 1467-1476, 2014
62014
Integrity, standards, and QC-related issues with big-data in pre-clinical drug discovery
JF Brothers, M Ung, R Escalante-Chong, J Ross, J Zhang, Y Cha, ...
Biochemical pharmacology, 2018
52018
Comprehensive genomic profiling of the lung transcriptome in emphysema and idiopathic pulmonary fibrosis using RNA-Seq
RL Kusko, J Brothers, G Liu, L Luo, BJ Guardela, J Tedrow, Y Aleksyev, ...
BMC Proceedings 6 (6), P21, 2012
52012
The host response to the bacterial lung tissue microbiome in chronic obstructive pulmonary disease
M Sze, PA Dimitriu, M Suzuki, JE McDonough, JD Campbell, JF Brothers, ...
A14. LIVE AND LET BREATHE: IMPACT OF VIRAL AND BACTERIAL INFECTIONS IN COPD …, 2014
32014
The role of microRNA 125a-3P in the pathogenesis of lung cancer
S Hazra, BK Gardner, K Krysan, TC Walser, J Brothers, JE Larsen, ...
JOURNAL OF THORACIC ONCOLOGY 5 (6), S222-S223, 2010
22010
The Role Of Metallothionein 1j Pseudogene In Chronic Obstructive Pulmonary Disease
M Sze, JD Campbell, JF Brothers, SYJ Yang, M Obeidat, WM Elliott, ...
Am J Respir Crit Care Med 191, A2888, 2015
2015
Distinct Transcriptomic And Epigenetic Networks Underlie Lung Tumors From Smokers With COPD
K Steiling, EA Vucic, JF Brothers, G Liu, YO Alekseyev, D Sin, S Lam, ...
C107. INFORMING LUNG DISEASE WITH BIOINFORMATICS, A5267-A5267, 2014
2014
Moving beyond gene expression: identification of lung-disease-associated novel transcripts and alternative splicing by RNA sequencing
J Brothers, R Kusko, G Liu, L Luo, BJ Guardela, J Tedrow, Y Alekesyev, ...
BMC Proceedings 6 (6), P4, 2012
2012
Comprehensive Genomic Profiling Of The Lung Transcriptome In Emphysema And Ipf Using Rna-Seq
J Brothers II, G Liu, L Luo, BJ Guardela, JR Tedrow, Y Aleksyev, IV Yang, ...
Health 5 (6), 7, 2012
2012
Gene Expression Profiles In Nasal Epithelium Differ Between Smokers With And Without Lung Cancer
C Anderlind, JF Brothers, M Lenburg, J Brody, A Spira
A18. SMOKE SIGNALS: ILLUMINATING NOVEL TARGETS FOR COPD AND EMPHYSEMA …, 2011
2011
Characterizing the Lung Disease Transcriptome with Next Generation RNA-sequencing
J Beane, JF Brothers, G Liu, L Luo, BJ Guardela, J Tedrow, Y Aleksyev, ...
Health 5, 6, 2011
2011
The Role Of Promoter Methylation In Regulating The Expression Of Genes Associated With COPD Progression
JF Brothers, S Neumann, JD Campbell, J Zeskind, ME Lenburg, ...
D65. FUNCTIONAL GENOMICS/PROTEOMICS OF DISEASE PATHOGENESIS, A6406-A6406, 2010
2010
Abstract A31: The role of microRNA 125a‐3P in the pathogenesis of lung cancer
S Hazra, BK Gardner, K Krysan, TC Walser, J Brothers, JE Larsen, ...
Cancer Prevention Research 3 (1 Supplement), A31-A31, 2010
2010
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