Suivre
Jacques-Philippe Colletier
Jacques-Philippe Colletier
Directeur de recherche, CNRS (DR2)
Adresse e-mail validée de ibs.fr
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The crystal structure of mouse VDAC1 at 2.3 Å resolution reveals mechanistic insights into metabolite gating
R Ujwal, D Cascio, JP Colletier, S Faham, J Zhang, L Toro, P Ping, ...
Proceedings of the National Academy of Sciences 105 (46), 17742-17747, 2008
6042008
Molecular basis for amyloid-β polymorphism
JP Colletier, A Laganowsky, M Landau, M Zhao, AB Soriaga, ...
Proceedings of the National Academy of Sciences 108 (41), 16938-16943, 2011
4422011
Protein encapsulation in liposomes: efficiency depends on interactions between protein and phospholipid bilayer.
JP Colletier, B Chaize, M Winterhalter, D Fournier
BMC biotechnology 2 (1), 1-8, 2002
3722002
The cytotoxic Staphylococcus aureus PSMα3 reveals a cross-α amyloid-like fibril
E Tayeb-Fligelman, O Tabachnikov, A Moshe, O Goldshmidt-Tran, ...
Science 355 (6327), 831-833, 2017
2852017
Discovery, biological evaluation, and crystal structure of a novel nanomolar selective butyrylcholinesterase inhibitor
B Brus, U Kosak, S Turk, A Pislar, N Coquelle, J Kos, J Stojan, JP Colletier, ...
Journal of medicinal chemistry 57 (19), 8167-8179, 2014
2502014
Translational diffusion of hydration water correlates with functional motions in folded and intrinsically disordered proteins
G Schirò, Y Fichou, FX Gallat, K Wood, F Gabel, M Moulin, M Härtlein, ...
Nature communications 6 (1), 6490, 2015
2262015
Structural insights into substrate traffic and inhibition in acetylcholinesterase
JP Colletier, D Fournier, HM Greenblatt, J Stojan, JL Sussman, G Zaccai, ...
The EMBO journal 25 (12), 2746-2756, 2006
2232006
Chromophore twisting in the excited state of a photoswitchable fluorescent protein captured by time-resolved serial femtosecond crystallography
N Coquelle, M Sliwa, J Woodhouse, G Schirò, V Adam, A Aquila, ...
Nature Chemistry 10 (1), 31-37, 2018
1832018
Flexibility of aromatic residues in the active-site gorge of acetylcholinesterase: X-ray versus molecular dynamics
Y Xu, JP Colletier, M Weik, H Jiang, J Moult, I Silman, JL Sussman
Biophysical Journal 95 (5), 2500-2511, 2008
1412008
Mechanisms of cholinesterase inhibition by inorganic mercury
MF Frasco, JP Colletier, M Weik, F Carvalho, L Guilhermino, J Stojan, ...
the FEBS Journal 274 (7), 1849-1861, 2007
1412007
Raster-scanning serial protein crystallography using micro-and nano-focused synchrotron beams
N Coquelle, AS Brewster, U Kapp, A Shilova, B Weinhausen, ...
Acta Crystallographica Section D: Biological Crystallography 71 (5), 1184-1196, 2015
1392015
Protein crystal structure obtained at 2.9 Å resolution from injecting bacterial cells into an X-ray free-electron laser beam
MR Sawaya, D Cascio, M Gingery, J Rodriguez, L Goldschmidt, ...
Proceedings of the National Academy of Sciences 111 (35), 12769-12774, 2014
1382014
Three-dimensional view of ultrafast dynamics in photoexcited bacteriorhodopsin
G Nass Kovacs, JP Colletier, ML Grünbein, Y Yang, T Stensitzki, A Batyuk, ...
Nature communications 10 (1), 3177, 2019
1372019
The magic of crystal structure-based inhibitor optimization: development of a butyrylcholinesterase inhibitor with picomolar affinity and in vivo activity
U Kosak, B Brus, D Knez, S Zakelj, J Trontelj, A Pislar, R Sink, M Jukic, ...
Journal of medicinal chemistry 61 (1), 119-139, 2018
1282018
Development of an in-vivo active reversible butyrylcholinesterase inhibitor
U Košak, B Brus, D Knez, R Šink, S Žakelj, J Trontelj, A Pišlar, J Šlenc, ...
Scientific reports 6 (1), 39495, 2016
1272016
Structural evidence that human acetylcholinesterase inhibited by tabun ages through O-dealkylation
E Carletti, JP Colletier, F Dupeux, M Trovaslet, P Masson, F Nachon
Journal of Medicinal Chemistry 53 (10), 4002-4008, 2010
1132010
De novo phasing with X-ray laser reveals mosquito larvicide BinAB structure
JP Colletier, MR Sawaya, M Gingery, JA Rodriguez, D Cascio, ...
Nature 539 (7627), 43-47, 2016
1112016
Crystallographic snapshots of nonaged and aged conjugates of soman with acetylcholinesterase, and of a ternary complex of the aged conjugate with pralidoxime
B Sanson, F Nachon, JP Colletier, MT Froment, L Toker, HM Greenblatt, ...
Journal of medicinal chemistry 52 (23), 7593-7603, 2009
1092009
Toxicity of eosinophil MBP is repressed by intracellular crystallization and promoted by extracellular aggregation
A Soragni, S Yousefi, C Stoeckle, AB Soriaga, MR Sawaya, E Kozlowski, ...
Molecular cell 57 (6), 1011-1021, 2015
1082015
Megahertz data collection from protein microcrystals at an X-ray free-electron laser
ML Grünbein, J Bielecki, A Gorel, M Stricker, R Bean, M Cammarata, ...
Nature communications 9 (1), 3487, 2018
1072018
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