Small extracellular vesicles are key regulators of non-cell autonomous intercellular communication in senescence via the interferon protein IFITM3 M Borghesan, J Fafián-Labora, O Eleftheriadou, P Carpintero-Fernández, ... Cell Reports 27 (13), 3956-3971. e6, 2019 | 216 | 2019 |
A senescence-centric view of aging: implications for longevity and disease M Borghesan, WMH Hoogaars, M Varela-Eirin, N Talma, M Demaria Trends in cell biology 30 (10), 777-791, 2020 | 169 | 2020 |
Integrin beta 3 regulates cellular senescence by activating the TGF-β pathway V Rapisarda, M Borghesan, V Miguela, V Encheva, AP Snijders, ... Cell reports 18 (10), 2480-2493, 2017 | 159 | 2017 |
Redox homeostasis and epigenetics in non-alcoholic fatty liver disease (NAFLD) C Podrini, M Borghesan, A Greco, V Pazienza, G Mazzoccoli, ... Current pharmaceutical design 19 (15), 2737-2746, 2013 | 114 | 2013 |
Cellular senescence as a potential mediator of COVID‐19 severity in the elderly J Nehme, M Borghesan, S Mackedenski, TG Bird, M Demaria Aging Cell 20 (9), 2020 | 97 | 2020 |
Physiological hypoxia restrains the senescence-associated secretory phenotype via AMPK-mediated mTOR suppression T van Vliet, M Varela-Eirin, B Wang, M Borghesan, SM Brandenburg, ... Molecular Cell, 2021 | 79 | 2021 |
Extracellular fluid viscosity enhances liver cancer cell mechanosensing and migration J Gonzalez-Molina, X Zhang, M Borghesan, JM da Silva, M Awan, B Fuller, ... Biomaterials 177, 113-124, 2018 | 78 | 2018 |
DNA hypomethylation and histone variant macroH2A1 synergistically attenuate chemotherapy-induced senescence to promote hepatocellular carcinoma progression M Borghesan, C Fusilli, F Rappa, C Panebianco, G Rizzo, JA Oben, ... Cancer research 76 (3), 594-606, 2016 | 78 | 2016 |
The role of cellular senescence in female reproductive aging and the potential for senotherapeutic interventions L Secomandi, M Borghesan, M Velarde, M Demaria Human reproduction update, 1-18, 2021 | 68 | 2021 |
Hepatic stellate cell senescence in liver fibrosis: Characteristics, mechanisms and perspectives M Zhang, S Serna-Salas, T , Damba, M Borghesan, M Demaria, ... Mechanisms of Ageing and Development 199 (111572), 2021 | 61 | 2021 |
SIRT1-metabolite binding histone macroH2A1. 1 protects hepatocytes against lipid accumulation V Pazienza, M Borghesan, T Mazza, F Sheedfar, C Panebianco, ... Aging (Albany NY) 6 (1), 35, 2014 | 57 | 2014 |
Caloric restriction and aging stem cells: the stick and the carrot? G Mazzoccoli, MF Tevy, M Borghesan, MR Delle Vergini, M Vinciguerra Experimental gerontology 50, 137-148, 2014 | 34 | 2014 |
Histone macroH2A1. 2 promotes metabolic health and leanness by inhibiting adipogenesis V Pazienza, C Panebianco, F Rappa, D Memoli, M Borghesan, S Cannito, ... Epigenetics & chromatin 9, 1-19, 2016 | 31 | 2016 |
Integrins in senescence and aging M Borghesan, A O'Loghlen Cell Cycle 16 (10), 909-910, 2017 | 24 | 2017 |
Prolonged hypoxia delays aging and preserves functionality of human amniotic fluid stem cells F Casciaro, M Borghesan, F Beretti, M Zavatti, E Bertucci, M Yung Follo, ... Mechanisms of Ageing and Development 191 (111328), 2020 | 14 | 2020 |
Histone variants and lipid metabolism M Borghesan, G Mazzoccoli, F Sheedfar, J Oben, V Pazienza, ... Biochemical Society Transactions 42 (5), 1409-1413, 2014 | 13 | 2014 |
Genome wide CRISPR/Cas9 screen identifies the coagulation factor IX (F9) as a regulator of senescence P Carpintero-Fernández, M Borghesan, O Eleftheriadou, B Pan-Castillo, ... Cell Death & Disease 13, 163, 2022 | 11 | 2022 |
The transcriptional regulators, the immune system and the the circadian clock. M Vinciguerra, M Borghesan, V Pazienza, A Piepoli, O Palmieri, ... Journal of Biological Regulators and Homeostatic Agents 27 (1), 9-22, 2013 | 8 | 2013 |
Circulating monocytes expressing senescence‐associated features are enriched in COVID‐19 patients with severe disease Y Lin, DF Postma, LS Steeneken, LS Melo Dos Santos, JL Kirkland, ... Aging Cell 22 (12), e14011, 2023 | 4 | 2023 |
Exosomes are key regulators of non-cell autonomous communication in senescence M Borghesan, J Fafián-Labora, P Carpintero-Fernández, ... bioRxiv, 356238, 2018 | 2 | 2018 |