John W. Semple
John W. Semple
Professor of Transfusion Medicine, Lund University
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Platelets and the immune continuum
JW Semple, JE Italiano, J Freedman
Nature Reviews Immunology 11 (4), 264-274, 2011
Platelet Toll-like receptor expression modulates lipopolysaccharide-induced thrombocytopenia and tumor necrosis factor-α production in vivo
R Aslam, ER Speck, M Kim, AR Crow, KWA Bang, FP Nestel, H Ni, ...
Blood 107 (2), 637-641, 2006
Differences in serum cytokine levels in acute and chronic autoimmune thrombocytopenic purpura: relationship to platelet phenotype and antiplatelet T-cell reactivity
JW Semple, Y Milev, D Cosgrave, M Mody, A Hornstein, V Blanchette, ...
Platelets release mitochondria serving as substrate for bactericidal group IIA-secreted phospholipase A2 to promote inflammation
LH Boudreau, AC Duchez, N Cloutier, D Soulet, N Martin, J Bollinger, ...
Blood, The Journal of the American Society of Hematology 124 (14), 2173-2183, 2014
Platelets and innate immunity
JW Semple, J Freedman
Cellular and Molecular Life Sciences 67 (4), 499-511, 2010
Pathogenesis and therapeutic mechanisms in immune thrombocytopenia (ITP)
A Zufferey, R Kapur, JW Semple
Journal of clinical medicine 6 (2), 16, 2017
Thrombocytopenia following pfizer and moderna SARS‐CoV‐2 vaccination
EJ Lee, DB Cines, T Gernsheimer, C Kessler, M Michel, MD Tarantino, ...
American journal of hematology, 2021
Increased antiplatelet T helper lymphocyte reactivity in patients with autoimmune thrombocytopenia
JW Semple, J Freedman
T granules in human platelets function in TLR9 organization and signaling
JN Thon, CG Peters, KR Machlus, R Aslam, J Rowley, H Macleod, ...
Journal of Cell Biology 198 (4), 561-574, 2012
Cellular immune dysfunction in immune thrombocytopenia (ITP)
CGJ McKenzie, L Guo, J Freedman, JW Semple
British journal of haematology 163 (1), 10-23, 2013
A murine model of severe immune thrombocytopenia is induced by antibody- and CD8+ T cell–mediated responses that are differentially sensitive to therapy
L Chow, R Aslam, ER Speck, M Kim, N Cridland, ML Webster, P Chen, ...
Blood, The Journal of the American Society of Hematology 115 (6), 1247-1253, 2010
Nouvelle cuisine: platelets served with inflammation
R Kapur, A Zufferey, E Boilard, JW Semple
The Journal of Immunology 194 (12), 5579-5587, 2015
HLA alloimmunization against platelet transfusions: pathophysiology, significance, prevention and management
K Pavenski, J Freedman, JW Semple
Tissue antigens 79 (4), 237-245, 2012
Platelet-bound lipopolysaccharide enhances Fc receptor–mediated phagocytosis of IgG-opsonized platelets
JW Semple, R Aslam, M Kim, ER Speck, J Freedman
Blood, The Journal of the American Society of Hematology 109 (11), 4803-4805, 2007
Cellular immune mechanisms in autoimmune thrombocytopenic purpura: An update
MD Coopamah, MB Garvey, J Freedman, JW Semple
Transfusion medicine reviews 17 (1), 69-80, 2003
Transfusion-associated circulatory overload and transfusion-related acute lung injury
JW Semple, J Rebetz, R Kapur
Blood, The Journal of the American Society of Hematology 133 (17), 1840-1853, 2019
Immune pathophysiology of autoimmune thrombocytopenic purpura
JW Semple
Blood reviews 16 (1), 9-12, 2002
IVIg inhibits reticuloendothelial system function and ameliorates murine passive‐immune thrombocytopenia independent of anti‐idiotype reactivity
AR Crow, S Song, JW Semple, J Freedman, AH Lazarus
British journal of haematology 115 (3), 679-686, 2001
Pathogenesis of immune thrombocytopenia
DB Cines, A Cuker, JW Semple
La Presse Médicale 43 (4), e49-e59, 2014
Recent progress in understanding the pathogenesis of immune thrombocytopenia
JW Semple, D Provan, MB Garvey, J Freedman
Current opinion in hematology 17 (6), 590-595, 2010
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