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Timothy Frankel
Timothy Frankel
Adresse e-mail validée de umich.edu
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Macrophage-released pyrimidines inhibit gemcitabine therapy in pancreatic cancer
CJ Halbrook, C Pontious, I Kovalenko, L Lapienyte, S Dreyer, HJ Lee, ...
Cell metabolism 29 (6), 1390-1399. e6, 2019
3252019
Validation of the American Joint Commission on Cancer (AJCC) staging system for patients with pancreatic adenocarcinoma: a Surveillance, Epidemiology and End Results (SEER …
SK Kamarajah, WR Burns, TL Frankel, CS Cho, H Nathan
Annals of surgical oncology 24, 2023-2030, 2017
2682017
Regulatory T-cell depletion alters the tumor microenvironment and accelerates pancreatic carcinogenesis
Y Zhang, J Lazarus, NG Steele, W Yan, HJ Lee, ZC Nwosu, CJ Halbrook, ...
Cancer discovery 10 (3), 422-439, 2020
2622020
PRC2 epigenetically silences Th1-type chemokines to suppress effector T-cell trafficking in colon cancer
N Nagarsheth, D Peng, I Kryczek, K Wu, W Li, E Zhao, L Zhao, S Wei, ...
Cancer research 76 (2), 275-282, 2016
2482016
Multimodal mapping of the tumor and peripheral blood immune landscape in human pancreatic cancer
NG Steele, ES Carpenter, SB Kemp, VR Sirihorachai, S The, L Delrosario, ...
Nature Cancer 1 (11), 1097-1112, 2020
2392020
A TCR targeting the HLA-A* 0201–restricted epitope of MAGE-A3 recognizes multiple epitopes of the MAGE-A antigen superfamily in several types of cancer
N Chinnasamy, JA Wargo, Z Yu, M Rao, TL Frankel, JP Riley, JJ Hong, ...
The Journal of Immunology 186 (2), 685-696, 2011
2082011
Inhibition of hedgehog signaling alters fibroblast composition in pancreatic cancer
NG Steele, G Biffi, SB Kemp, Y Zhang, D Drouillard, LJ Syu, Y Hao, ...
Clinical Cancer Research 27 (7), 2023-2037, 2021
1702021
Inhibition of ATM increases interferon signaling and sensitizes pancreatic cancer to immune checkpoint blockade therapy
Q Zhang, MD Green, X Lang, J Lazarus, JD Parsels, S Wei, LA Parsels, ...
Cancer research 79 (15), 3940-3951, 2019
1672019
The role of tumor microenvironment in cancer immunotherapy
T Frankel, MP Lanfranca, W Zou
Tumor Immune Microenvironment in Cancer Progression and Cancer Therapy, 51-64, 2017
1532017
Critical evaluation of the American Joint Commission on Cancer (AJCC) staging system for patients with Hepatocellular Carcinoma (HCC): a Surveillance, Epidemiology, End Results …
SK Kamarajah, TL Frankel, C Sonnenday, CS Cho, H Nathan
Journal of surgical oncology 117 (4), 644-650, 2018
1422018
Biological and pathological activities of interleukin-22
M Perusina Lanfranca, Y Lin, J Fang, W Zou, T Frankel
Journal of molecular medicine 94, 523-534, 2016
1362016
Hepatic resection for colorectal metastases
TL Frankel, MI D'Angelica
Journal of Surgical Oncology 109 (1), 2-7, 2014
1202014
Both CD4 and CD8 T cells mediate equally effective in vivo tumor treatment when engineered with a highly avid TCR targeting tyrosinase
TL Frankel, WR Burns, PD Peng, Z Yu, D Chinnasamy, JA Wargo, ...
The Journal of Immunology 184 (11), 5988-5998, 2010
1172010
A high molecular weight melanoma-associated antigen–specific chimeric antigen receptor redirects lymphocytes to target human melanomas
WR Burns, Y Zhao, TL Frankel, CS Hinrichs, Z Zheng, H Xu, SA Feldman, ...
Cancer research 70 (8), 3027-3033, 2010
1172010
Preoperative imaging for hepatic resection of colorectal cancer metastasis
TL Frankel, RKG Do, WR Jarnagin
Journal of gastrointestinal oncology 3 (1), 11, 2012
922012
Spatial and phenotypic immune profiling of metastatic colon cancer
J Lazarus, T Maj, JJ Smith, MP Lanfranca, A Rao, MI D’Angelica, ...
JCI insight 3 (22), 2018
782018
Murine-and human-derived autologous organoid/immune cell co-cultures as pre-clinical models of pancreatic ductal adenocarcinoma
L Holokai, J Chakrabarti, J Lundy, D Croagh, P Adhikary, SS Richards, ...
Cancers 12 (12), 3816, 2020
712020
IFNγ signaling integrity in colorectal cancer immunity and immunotherapy
W Du, TL Frankel, M Green, W Zou
Cellular & molecular immunology 19 (1), 23-32, 2022
702022
Pancreatic cancer is marked by complement-high blood monocytes and tumor-associated macrophages
SB Kemp, NG Steele, ES Carpenter, KL Donahue, GG Bushnell, ...
Life science alliance 4 (6), 2021
682021
Coaltered Ras/B-raf and TP53 is associated with extremes of survivorship and distinct patterns of metastasis in patients with metastatic colorectal cancer
J Datta, JJ Smith, WK Chatila, JC McAuliffe, C Kandoth, E Vakiani, ...
Clinical Cancer Research 26 (5), 1077-1085, 2020
652020
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