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Edward A. Fon
Edward A. Fon
Montreal Neurological Institute, McGill University
Adresse e-mail validée de mcgill.ca
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Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)1
DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ...
autophagy 17 (1), 1-382, 2021
13112*2021
Ubiquitin is phosphorylated by PINK1 to activate parkin
F Koyano, K Okatsu, H Kosako, Y Tamura, E Go, M Kimura, Y Kimura, ...
Nature 510 (7503), 162-166, 2014
14382014
A new pathway for mitochondrial quality control: mitochondrial‐derived vesicles
A Sugiura, GL McLelland, EA Fon, HM McBride
The EMBO journal 33 (19), 2142-2156, 2014
7602014
Parkin and PINK 1 function in a vesicular trafficking pathway regulating mitochondrial quality control
GL McLelland, V Soubannier, CX Chen, HM McBride, EA Fon
The EMBO journal 33 (4), 282-295, 2014
7412014
Mitochondrial processing peptidase regulates PINK1 processing, import and Parkin recruitment
AW Greene, K Grenier, MA Aguileta, S Muise, R Farazifard, ME Haque, ...
EMBO reports 13 (4), 378-385, 2012
7352012
A vesicular transport pathway shuttles cargo from mitochondria to lysosomes
V Soubannier, GL McLelland, R Zunino, E Braschi, P Rippstein, EA Fon, ...
Current Biology 22 (2), 135-141, 2012
6892012
Mitochondrial dysfunction and mitophagy in Parkinson's: from familial to sporadic disease
BJ Ryan, S Hoek, EA Fon, R Wade-Martins
Trends in biochemical sciences 40 (4), 200-210, 2015
5852015
Structure of parkin reveals mechanisms for ubiquitin ligase activation
JF Trempe, V Sauvé, K Grenier, M Seirafi, MY Tang, M Ménade, ...
Science 340 (6139), 1451-1455, 2013
5412013
Loss of the Parkinson's disease-linked gene DJ-1 perturbs mitochondrial dynamics
I Irrcher, H Aleyasin, EL Seifert, SJ Hewitt, S Chhabra, M Phillips, AK Lutz, ...
Human molecular genetics 19 (19), 3734-3746, 2010
4512010
A regulated interaction with the UIM protein Eps15 implicates parkin in EGF receptor trafficking and PI (3) K–Akt signalling
L Fallon, CML Bélanger, AT Corera, M Kontogiannea, E Regan-Klapisz, ...
Nature cell biology 8 (8), 834-842, 2006
4302006
Vesicular transport regulates monoamine storage and release but is not essential for amphetamine action
EA Fon, EN Pothos, BC Sun, N Killeen, D Sulzer, RH Edwards
Neuron 19 (6), 1271-1283, 1997
4031997
The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications
TM Durcan, EA Fon
Genes & development 29 (10), 989-999, 2015
3922015
Methamphetamine-induced degeneration of dopaminergic neurons involves autophagy and upregulation of dopamine synthesis
KE Larsen, EA Fon, TG Hastings, RH Edwards, D Sulzer
Journal of Neuroscience 22 (20), 8951-8960, 2002
3832002
In situ hybridization evidence for angiotensinogen messenger RNA in the rat proximal tubule. An hypothesis for the intrarenal renin angiotensin system.
JR Ingelfinger, WM Zuo, EA Fon, KE Ellison, VJ Dzau
The Journal of clinical investigation 85 (2), 417-423, 1990
3821990
USP 8 regulates mitophagy by removing K 6‐linked ubiquitin conjugates from parkin
TM Durcan, MY Tang, JR Pérusse, EA Dashti, MA Aguileta, GL McLelland, ...
The EMBO journal 33 (21), 2473-2491, 2014
3742014
Mfn2 ubiquitination by PINK1/parkin gates the p97-dependent release of ER from mitochondria to drive mitophagy
GL McLelland, T Goiran, W Yi, G Dorval, CX Chen, ND Lauinger, AI Krahn, ...
Elife 7, e32866, 2018
3022018
BAG5 inhibits parkin and enhances dopaminergic neuron degeneration
SK Kalia, S Lee, PD Smith, L Liu, SJ Crocker, TE Thorarinsdottir, ...
Neuron 44 (6), 931-945, 2004
2422004
Parkin and CASK/LIN-2 associate via a PDZ-mediated interaction and are co-localized in lipid rafts and postsynaptic densities in brain
L Fallon, F Moreau, BG Croft, N Labib, WJ Gu, EA Fon
Journal of Biological Chemistry 277 (1), 486-491, 2002
2382002
Syntaxin-17 delivers PINK1/parkin-dependent mitochondrial vesicles to the endolysosomal system
GL McLelland, SA Lee, HM McBride, EA Fon
Journal of Cell Biology 214 (3), 275-291, 2016
2202016
Expression of a putative vesicular acetylcholine transporter facilitates quantal transmitter packaging
H Song, G Ming, E Fon, E Bellocchio, RH Edwards, M Poo
Neuron 18 (5), 815-826, 1997
1971997
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