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| An improved zinc-finger nuclease architecture for highly specific genome editing JC Miller, MC Holmes, J Wang, DY Guschin, YL Lee, I Rupniewski, ... Nature biotechnology 25 (7), 778, 2007 | 1494 | 2007 |
| Establishment of HIV-1 resistance in CD4+ T cells by genome editing using zinc-finger nucleases EE Perez, J Wang, JC Miller, Y Jouvenot, KA Kim, O Liu, N Wang, G Lee, ... Nature biotechnology 26 (7), 808, 2008 | 1383 | 2008 |
| Selective recruitment of CCR4-bearing Th2 cells toward antigen-presenting cells by the CC chemokines thymus and activation-regulated chemokine and macrophage-derived chemokine T Imai, M Nagira, S Takagi, M Kakizaki, M Nishimura, J Wang, PW Gray, ... International immunology 11 (1), 81-88, 1999 | 852 | 1999 |
| Human hematopoietic stem/progenitor cells modified by zinc-finger nucleases targeted to CCR5 control HIV-1 in vivo N Holt, J Wang, K Kim, G Friedman, X Wang, V Taupin, GM Crooks, ... Nature biotechnology 28 (8), 839, 2010 | 829 | 2010 |
| An unbiased genome-wide analysis of zinc-finger nuclease specificity R Gabriel, A Lombardo, A Arens, JC Miller, P Genovese, C Kaeppel, ... Nature biotechnology 29 (9), 816, 2011 | 724 | 2011 |
| Enhancing zinc-finger-nuclease activity with improved obligate heterodimeric architectures Y Doyon, TD Vo, MC Mendel, SG Greenberg, J Wang, DF Xia, JC Miller, ... Nature methods 8 (1), 74, 2011 | 524 | 2011 |
| Evolution of the aging brain transcriptome and synaptic regulation PM Loerch, T Lu, KA Dakin, JM Vann, A Isaacs, C Geula, J Wang, Y Pan, ... PloS one 3 (10), e3329, 2008 | 350 | 2008 |
| Methods and compositions for targeted single-stranded cleavage and targeted integration J Wang US Patent 8,703,489, 2014 | 321 | 2014 |
| Homology-driven genome editing in hematopoietic stem and progenitor cells using ZFN mRNA and AAV6 donors J Wang, CM Exline, JJ DeClercq, GN Llewellyn, SB Hayward, PWL Li, ... Nature biotechnology 33 (12), 1256, 2015 | 308 | 2015 |
| CD16+ monocytes produce IL-6, CCL2, and matrix metalloproteinase-9 upon interaction with CX3CL1-expressing endothelial cells P Ancuta, J Wang, D Gabuzda Journal of leukocyte biology 80 (5), 1156-1164, 2006 | 268 | 2006 |
| Genomic editing of the HIV-1 coreceptor CCR5 in adult hematopoietic stem and progenitor cells using zinc finger nucleases L Li, L Krymskaya, J Wang, J Henley, A Rao, LF Cao, CA Tran, ... Molecular Therapy 21 (6), 1259-1269, 2013 | 216 | 2013 |
| The HIV Env variant N283 enhances macrophage tropism and is associated with brain infection and dementia RL Dunfee, ER Thomas, PR Gorry, J Wang, J Taylor, K Kunstman, ... Proceedings of the National Academy of Sciences 103 (41), 15160-15165, 2006 | 211 | 2006 |
| Targeted correction and restored function of the CFTR gene in cystic fibrosis induced pluripotent stem cells AM Crane, P Kramer, JH Bui, WJ Chung, XS Li, ML Gonzalez-Garay, ... Stem Cell Reports 4 (4), 569, 2015 | 207 | 2015 |
| Methods and compositions for treatment of a genetic condition A Conway, GJ Cost, R DeKelver, EJ Rebar, A Reik, F Urnov, J Wang, ... US Patent 9,873,894, 2018 | 204 | 2018 |
| Simultaneous zinc-finger nuclease editing of the HIV coreceptors ccr5 and cxcr4 protects CD4+ T cells from HIV-1 infection CA Didigu, CB Wilen, J Wang, J Duong, AJ Secreto, GA Danet-Desnoyers, ... Blood 123 (1), 61-69, 2014 | 199 | 2014 |
| Tumor necrosis factor (TNF) is a physiologic regulator of hematopoietic progenitor cells: increase of early hematopoietic progenitor cells in TNF receptor p55-deficient mice in … Y Zhang, A Harada, H Bluethmann, JB Wang, S Nakao, N Mukaida, ... Blood 86 (8), 2930-2937, 1995 | 194 | 1995 |
| Engineering HIV-resistant human CD4+ T cells with CXCR4-specific zinc-finger nucleases CB Wilen, J Wang, JC Tilton, JC Miller, KA Kim, EJ Rebar, SA Sherrill-Mix, ... PLoS pathogens 7 (4), e1002020, 2011 | 179 | 2011 |
| Targeted gene addition to a predetermined site in the human genome using a ZFN-based nicking enzyme J Wang, G Friedman, Y Doyon, NS Wang, CJ Li, JC Miller, KL Hua, JJ Yan, ... Genome research 22 (7), 1316-1326, 2012 | 170 | 2012 |
| Highly efficient homology-driven genome editing in human T cells by combining zinc-finger nuclease mRNA and AAV6 donor delivery J Wang, JJ DeClercq, SB Hayward, PWL Li, DA Shivak, PD Gregory, ... Nucleic acids research 44 (3), e30-e30, 2015 | 159 | 2015 |
