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Thomas Vierbuchen
Thomas Vierbuchen
Assistant Member, Developmental Biology Program, Sloan Kettering Institute, Memorial Sloan Kettering
Adresse e-mail validée de mskcc.org - Page d'accueil
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Direct conversion of fibroblasts to functional neurons by defined factors
T Vierbuchen, A Ostermeier, ZP Pang, Y Kokubu, TC Südhof, M Wernig
Nature 463 (7284), 1035-1041, 2010
36362010
Induction of human neuronal cells by defined transcription factors
ZP Pang*, N Yang*, T Vierbuchen*, A Ostermeier, DR Fuentes, TQ Yang, ...
Nature 476 (7359), 220-223, 2011
14752011
Hierarchical mechanisms for direct reprogramming of fibroblasts to neurons
OL Wapinski*, T Vierbuchen*, K Qu, QY Lee, S Chanda, DR Fuentes, ...
Cell 155 (3), 621-635, 2013
6332013
AP-1 Transcription Factors and the BAF Complex Mediate Signal-Dependent Enhancer Selection
T Vierbuchen*, E Ling*, CJ Cowley, CH Couch, X Wang, DA Harmin, ...
Molecular Cell 68 (6), 1067-1082, 2017
3522017
Generation of oligodendroglial cells by direct lineage conversion
N Yang, JB Zuchero, H Ahlenius, S Marro, YH Ng, T Vierbuchen, ...
Nature biotechnology 31 (5), 434-439, 2013
3512013
Direct lineage conversions: unnatural but useful?
T Vierbuchen, M Wernig
Nature biotechnology 29 (10), 892-907, 2011
2982011
Genome-wide identification and characterization of functional neuronal activity-dependent enhancers
AN Malik*, T Vierbuchen*, M Hemberg, AA Rubin, E Ling, CH Couch, ...
Nature neuroscience, 2014
2682014
Molecular roadblocks for cellular reprogramming
T Vierbuchen, M Wernig
Molecular cell 47 (6), 827-838, 2012
2232012
Myt1l safeguards neuronal identity by actively repressing many non-neuronal fates
M Mall, MS Kareta, S Chanda, H Ahlenius, N Perotti, B Zhou, SD Grieder, ...
Nature 544 (7649), 245-249, 2017
2072017
FOXO3 shares common targets with ASCL1 genome-wide and inhibits ASCL1-dependent neurogenesis
AE Webb, EA Pollina, T Vierbuchen, N Urbán, D Ucar, DS Leeman, ...
Cell reports 4 (3), 477-491, 2013
1542013
Characterization of human mosaic Rett syndrome brain tissue by single-nucleus RNA sequencing
W Renthal, LD Boxer, S Hrvatin, E Li, A Silberfeld, MA Nagy, EC Griffith, ...
Nature neuroscience 21 (12), 1670-1679, 2018
1062018
Direct conversion of cells to cells of other lineages
M Wernig, TC Sudhof, T Vierbuchen, A Ostermeier, Z Pang
US Patent 9,057,053, 2015
242015
A bipartite element with allele-specific functions safeguards DNA methylation imprints at the Dlk1-Dio3 locus
BE Aronson, L Scourzic, V Shah, E Swanzey, A Kloetgen, A Polyzos, ...
Developmental cell 56 (22), 3052-3065. e5, 2021
152021
Characterization of sequence determinants of enhancer function using natural genetic variation
MG Yang, E Ling, CJ Cowley, ME Greenberg, T Vierbuchen
Elife 11, e76500, 2022
122022
Dynamic network-guided CRISPRi screen identifies CTCF-loop-constrained nonlinear enhancer gene regulatory activity during cell state transitions
R Luo, J Yan, JW Oh, W Xi, D Shigaki, W Wong, HS Cho, D Murphy, ...
Nature genetics 55 (8), 1336-1346, 2023
10*2023
Chromatin regulation of transcriptional enhancers and cell fate by the Sotos syndrome gene NSD1
Z Sun, Y Lin, MT Islam, R Koche, L Hedehus, D Liu, C Huang, ...
Molecular Cell 83 (14), 2398-2416. e12, 2023
82023
Rapid and robust directed differentiation of mouse epiblast stem cells into definitive endoderm and forebrain organoids
D Medina-Cano, EK Corrigan, RA Glenn, MT Islam, Y Lin, J Kim, H Cho, ...
Development 149 (20), dev200561, 2022
42022
Direct conversion of cells to cells of other lineages
M Wernig, TC Sudhof, T Vierbuchen, A Ostermeier, Z Pang
US Patent App. 15/651,910, 2017
12017
WNK1 enforces macrophage lineage fidelity
AJ Trzeciak, WS Rojas, ZL Liu, AS Krebs, Z Wang, PHV Saavedra, ...
bioRxiv, 2023.04. 26.538482, 2023
2023
WNK1 enforces macrophage lineage fidelity
J Perry, A Trzeciak, WS Rojas, A Krebs, G Zago, YT Wang, Z Wang, ...
2022
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