| I-motif DNA structures are formed in the nuclei of human cells M Zeraati, DB Langley, P Schofield, AL Moye, R Rouet, WE Hughes, ... Nature chemistry 10 (6), 631-637, 2018 | 490 | 2018 |
| CRISPR-Cpf1 mediates efficient homology-directed repair and temperature-controlled genome editing MA Moreno-Mateos, JP Fernandez, R Rouet, CE Vejnar, MA Lane, E Mis, ... Nature communications 8 (1), 2024, 2017 | 272 | 2017 |
| Redemption of autoantibodies on anergic B cells by variable-region glycosylation and mutation away from self-reactivity Z Sabouri, P Schofield, K Horikawa, E Spierings, D Kipling, KL Randall, ... Proceedings of the National Academy of Sciences 111 (25), E2567-E2575, 2014 | 269 | 2014 |
| General strategy for the generation of human antibody variable domains with increased aggregation resistance K Dudgeon, R Rouet, I Kokmeijer, P Schofield, J Stolp, D Langley, ... Proceedings of the National Academy of Sciences 109 (27), 10879-10884, 2012 | 218 | 2012 |
| CAF hierarchy driven by pancreatic cancer cell p53-status creates a pro-metastatic and chemoresistant environment via perlecan C Vennin, P Mélénec, R Rouet, M Nobis, AS Cazet, KJ Murphy, ... Nature communications 10 (1), 3637, 2019 | 200 | 2019 |
| Aggregation, stability, and formulation of human antibody therapeutics D Lowe, K Dudgeon, R Rouet, P Schofield, L Jermutus, D Christ Advances in protein chemistry and structural biology 84, 41-61, 2011 | 197 | 2011 |
| Receptor-mediated delivery of CRISPR-Cas9 endonuclease for cell-type-specific gene editing R Rouet, BA Thuma, MD Roy, NG Lintner, DM Rubitski, JE Finley, ... Journal of the American Chemical Society 140 (21), 6596-6603, 2018 | 154 | 2018 |
| Stability engineering of the human antibody repertoire R Rouet, D Lowe, D Christ FEBS letters 588 (2), 269-277, 2014 | 115 | 2014 |
| Next-generation sequencing of antibody display repertoires R Rouet, KJL Jackson, DB Langley, D Christ Frontiers in immunology 9, 118, 2018 | 87 | 2018 |
| Long-term persistence of RBD+ memory B cells encoding neutralizing antibodies in SARS-CoV-2 infection A Abayasingam, H Balachandran, D Agapiou, M Hammoud, C Rodrigo, ... Cell reports Medicine 2 (4), 2021 | 74 | 2021 |
| Expression of high-affinity human antibody fragments in bacteria R Rouet, D Lowe, K Dudgeon, B Roome, P Schofield, D Langley, ... nature protocols 7 (2), 364-373, 2012 | 74 | 2012 |
| Fully human VH single domains that rival the stability and cleft recognition of camelid antibodies R Rouet, K Dudgeon, M Christie, D Langley, D Christ Journal of Biological Chemistry 290 (19), 11905-11917, 2015 | 62 | 2015 |
| Optimized CRISPR-Cpf1 system for genome editing in zebrafish JP Fernandez, CE Vejnar, AJ Giraldez, R Rouet, MA Moreno-Mateos Methods 150, 11-18, 2018 | 44 | 2018 |
| Immunizations with diverse sarbecovirus receptor-binding domains elicit SARS-CoV-2 neutralizing antibodies against a conserved site of vulnerability DL Burnett, KJL Jackson, DB Langley, A Aggarwal, AO Stella, ... Immunity 54 (12), 2908-2921. e6, 2021 | 43 | 2021 |
| Large expert-curated database for benchmarking document similarity detection in biomedical literature search P Brown, AC Tan, MA El-Esawi, T Liehr, O Blanck, DP Gladue, ... Database 2019, 2019 | 34 | 2019 |
| Bispecific antibodies with native chain structure R Rouet, D Christ Nature biotechnology 32 (2), 136-137, 2014 | 27 | 2014 |
| Structural basis for epitope masking and strain specificity of a conserved epitope in an intrinsically disordered malaria vaccine candidate RAV Morales, CA MacRaild, J Seow, B Krishnarjuna, N Drinkwater, ... Scientific reports 5 (1), 10103, 2015 | 26 | 2015 |
| Potent SARS-CoV-2 binding and neutralization through maturation of iconic SARS-CoV-1 antibodies R Rouet, O Mazigi, GJ Walker, DB Langley, M Sobti, P Schofield, ... MAbs 13 (1), 1922134, 2021 | 24 | 2021 |
| Rapid prediction of expression and refolding yields using phage display K Dudgeon, R Rouet, D Christ Protein Engineering, Design & Selection 26 (10), 671-674, 2013 | 23 | 2013 |
| Structure-based design of a highly stable, covalently-linked SARS-CoV-2 spike trimer with improved structural properties and immunogenicity E Olmedillas, CJ Mann, W Peng, YT Wang, RD Avalos, D Bedinger, ... bioRxiv, 2021.05. 06.441046, 2021 | 22 | 2021 |
