| A reference map of the human binary protein interactome K Luck, DK Kim, L Lambourne, K Spirohn, BE Begg, W Bian, R Brignall, ... Nature 580 (7803), 402-408, 2020 | 902 | 2020 |
| BRCA1 recruitment to transcriptional pause sites is required for R-loop-driven DNA damage repair E Hatchi, K Skourti-Stathaki, S Ventz, L Pinello, A Yen, ... Molecular cell 57 (4), 636-647, 2015 | 448 | 2015 |
| E4F1 is an atypical ubiquitin ligase that modulates p53 effector functions independently of degradation L Le Cam, LK Linares, C Paul, E Julien, M Lacroix, E Hatchi, R Triboulet, ... Cell 127 (4), 775-788, 2006 | 284 | 2006 |
| MAPK Pathway Suppression Unmasks Latent DNA Repair Defects and Confers a Chemical Synthetic Vulnerability in BRAF-, NRAS-, and NF1-Mutant Melanomas O Maertens, R Kuzmickas, HE Manchester, CE Emerson, AG Gavin, ... Cancer discovery 9 (4), 526-545, 2019 | 76 | 2019 |
| BRCA1 binds TERRA RNA and suppresses R-Loop-based telomeric DNA damage J Vohhodina, LJ Goehring, B Liu, Q Kong, VV Botchkarev Jr, M Huynh, ... Nature communications 12 (1), 3542, 2021 | 65 | 2021 |
| CARM1 inhibition enables immunotherapy of resistant tumors by dual action on tumor cells and T cells S Kumar, Z Zeng, A Bagati, RE Tay, LA Sanz, SR Hartono, Y Ito, ... Cancer discovery 11 (8), 2050-2071, 2021 | 53 | 2021 |
| The transcription factor E4F1 coordinates CHK1-dependent checkpoint and mitochondrial functions G Rodier, O Kirsh, M Baraibar, T Houles, M Lacroix, H Delpech, E Hatchi, ... Cell reports 11 (2), 220-233, 2015 | 44 | 2015 |
| Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis M Lacroix, J Caramel, P Goguet-Rubio, LK Linares, S Estrach, E Hatchi, ... Proceedings of the National Academy of Sciences 107 (49), 21076-21081, 2010 | 40 | 2010 |
| BRCA1 and RNAi factors promote repair mediated by small RNAs and PALB2–RAD52 E Hatchi, L Goehring, S Landini, K Skourti-Stathaki, DK DeConti, ... https://www.nature.com/articles/s41586-020-03150-2 591 (7851), 665-670, 2021 | 35 | 2021 |
| E4F1 deficiency results in oxidative stress–mediated cell death of leukemic cells E Hatchi, G Rodier, M Lacroix, J Caramel, O Kirsh, C Jacquet, E Schrepfer, ... Journal of Experimental Medicine 208 (7), 1403-1417, 2011 | 23 | 2011 |
| MAPK pathway suppression unmasks latent DNA repair defects and confers a chemical synthetic vulnerability in BRAF-, NRAS-, and NF1-mutant melanomas. Cancer Discov. 2019; 9: 526 … O Maertens, R Kuzmickas, HE Manchester, CE Emerson, AG Gavin, ... DOI: https://doi. org/10.1158/2159-8290. CD-18-0879. PMID: https://www. ncbi …, 0 | 20 | |
| E4F1 dysfunction results in autophagic cell death in myeloid leukemic cells E Hatchi, G Rodier, C Sardet, L Le Cam Autophagy 7 (12), 1566-1567, 2011 | 10 | 2011 |
| Opening a door to PARP inhibitor-induced lethality in HR-proficient human tumor cells E Hatchi, DM Livingston Cancer cell 37 (2), 139-140, 2020 | 9 | 2020 |
| Transcription factor E4F1 is essential for epidermal stem cell maintenance and skin homeostasis (vol 107, pg 21076, 2010) M Lacroix, J Caramel, P Goguet-Rubio, LK Linares, S Estrach, E Hatchi, ... PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF …, 2012 | 1 | 2012 |
| Abstract LB-113: MAPK pathway suppression unmasks latent DNA repair defects and confers a chemical synthetic vulnerability inBRAF,NRASandNF1-mutant … O Maertens, R Kuzmickas, H Manchester, C Emerson, A Gavin, C Guild, ... Cancer Research 79 (13_Supplement), LB-113-LB-113, 2019 | | 2019 |
| Détermination des fonctions in vivo d'E4F1 au cours de la tumorigenèse: E4F1 E Hatchi | | 2009 |
| Determination of E4F1 functions in tumorigenesis (E4F1) E HATCHI Université de Montpellier 2 Sciences et Techniques du Languedoc, Montpellier, 2009 | | 2009 |
| E4F1-mediated ubiquitylation of p63 regulates epidermal homeostasis M Lacroix, J Caramel, L Linares, C De Bettignies, E Hatchi, A Thepot, ... BULLETIN DU CANCER 95, S22-S22, 2008 | | 2008 |
| Determination of the E4F1 role in tumorigenesis E Hatchi, S Lagarrigue, C Sardet, CL Le BULLETIN DU CANCER 95, S43-S43, 2008 | | 2008 |
| E4F1: a new therapeutic target in cancer treatment? E Hatchi, M Lacroix, E Schrepfer, S Laguarrigue, LK Linares, C Paul, ... BULLETIN DU CANCER 95, S17-S17, 2008 | | 2008 |
Giovanni ParmigianiProfessor Department of Data Science, DFCIAdresse e-mail validée de dfci.harvard.edu
