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Carol Sheppard
Carol Sheppard
Research Fellow, Imperial College London
Adresse e-mail validée de imperial.ac.uk - Page d'accueil
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The SARS-CoV-2 variants associated with infections in India, B. 1.617, show enhanced spike cleavage by furin
TP Peacock, CM Sheppard, JC Brown, N Goonawardane, J Zhou, ...
BioRxiv, 2021.05. 28.446163, 2021
952021
RASSF7 is a member of a new family of RAS association domain–containing proteins and is required for completing mitosis
V Sherwood, R Manbodh, C Sheppard, AD Chalmers
Molecular biology of the cell 19 (4), 1772-1782, 2008
762008
ANP32 proteins are essential for influenza virus replication in human cells
E Staller, CM Sheppard, PJ Neasham, B Mistry, TP Peacock, DH Goldhill, ...
Journal of virology 93 (17), 10.1128/jvi. 00217-19, 2019
752019
Archaeal TFEα/β is a hybrid of TFIIE and the RNA polymerase III subcomplex hRPC62/39
F Blombach, E Salvadori, T Fouqueau, J Yan, J Reimann, C Sheppard, ...
Elife 4, e08378, 2015
562015
Structural and mechanistic basis for the inhibition of Escherichia coli RNA polymerase by T7 Gp2
E James, M Liu, C Sheppard, V Mekler, B Cámara, B Liu, P Simpson, ...
Molecular cell 47 (5), 755-766, 2012
462012
Molecular mechanism of transcription inhibition by phage T7 gp2 protein
V Mekler, L Minakhin, C Sheppard, S Wigneshweraraj, K Severinov
Journal of molecular biology 413 (5), 1016-1027, 2011
392011
Host determinants of influenza RNA synthesis
TP Peacock, CM Sheppard, E Staller, WS Barclay
Annual review of virology 6, 215-233, 2019
372019
The SARS-CoV-2 variants associated with infections in India
TP Peacock, CM Sheppard, JC Brown, N Goonawardane, J Zhou, ...
B 1, 1-10, 2021
352021
Key Roles of the Downstream Mobile Jaw of Escherichia coli RNA Polymerase in Transcription Initiation
A Drennan, M Kraemer, M Capp, T Gries, E Ruff, C Sheppard, ...
Biochemistry 51 (47), 9447-9459, 2012
312012
A bacteriophage transcription regulator inhibits bacterial transcription initiation by σ-factor displacement
B Liu, A Shadrin, C Sheppard, V Mekler, Y Xu, K Severinov, S Matthews, ...
Nucleic acids research 42 (7), 4294-4305, 2014
302014
Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP
C Sheppard, F Blombach, A Belsom, S Schulz, T Daviter, K Smollett, ...
Nature Communications 7 (1), 13595, 2016
252016
Conformational heterogeneity and bubble dynamics in single bacterial transcription initiation complexes
D Duchi, K Gryte, NC Robb, Z Morichaud, C Sheppard, K Brodolin, ...
Nucleic acids research 46 (2), 677-688, 2018
202018
Inhibition of Escherichia coli RNAp by T7 Gp2 protein: role of negatively charged strip of amino acid residues in Gp2
C Sheppard, B Cámara, A Shadrin, N Akulenko, M Liu, G Baldwin, ...
Journal of molecular biology 407 (5), 623-632, 2011
202011
Structure and mechanisms of viral transcription factors in archaea
C Sheppard, F Werner
Extremophiles 21 (5), 829-838, 2017
182017
The C-terminal LCAR of host ANP32 proteins interacts with the influenza A virus nucleoprotein to promote the replication of the viral RNA genome
F Wang, CM Sheppard, B Mistry, E Staller, WS Barclay, JM Grimes, ...
Nucleic acids research 50 (10), 5713-5725, 2022
162022
Consortium PV, de Silva TI, Barclay WS The SARS-CoV-2 variants associated with infections in India, B. 1.617, show enhanced spike cleavage by furin
TP Peacock, CM Sheppard, JC Brown, N Goonawardane, J Zhou, ...
BioRxiv, 2021
132021
Substitutions in the Escherichia coli RNA polymerase inhibitor T7 Gp2 that allow inhibition of transcription when the primary interaction interface between Gp2 and …
A Shadrin, C Sheppard, K Severinov, S Matthews, S Wigneshweraraj
Microbiology 158 (11), 2753-2764, 2012
132012
Mammalian ANP32A and ANP32B proteins drive differential polymerase adaptations in avian influenza virus
TP Peacock, CM Sheppard, MG Lister, E Staller, R Frise, OC Swann, ...
Journal of virology 97 (5), e00213-23, 2023
112023
A non-bacterial transcription factor inhibits bacterial transcription by a multipronged mechanism
C Sheppard, E James, G Barton, S Matthews, K Severinov, ...
RNA biology 10 (4), 495-501, 2013
112013
Creating resistance to avian influenza infection through genome editing of the ANP32 gene family
A Idoko-Akoh, DH Goldhill, CM Sheppard, D Bialy, JL Quantrill, ...
Nature Communications 14 (1), 6136, 2023
102023
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