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Mathieu Bottier
Mathieu Bottier
Royal Brompton Hospital
Adresse e-mail validée de rbht.nhs.uk
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Année
How does cilium length affect beating?
M Bottier, KA Thomas, SK Dutcher, PV Bayly
Biophysical journal 116 (7), 1292-1304, 2019
492019
Axonemal structures reveal mechanoregulatory and disease mechanisms
T Walton, M Gui, S Velkova, MR Fassad, RA Hirst, E Haarman, ...
Nature 618 (7965), 625-633, 2023
402023
Pathogenesis of chronic rhinosinusitis with nasal polyps: role of IL-6 in airway epithelial cell dysfunction
E Bequignon, D Mangin, J Bécaud, J Pasquier, C Angely, M Bottier, ...
Journal of Translational Medicine 18, 1-12, 2020
392020
A new index for characterizing micro-bead motion in a flow induced by ciliary beating: Part I, experimental analysis
M Bottier, S Blanchon, G Pelle, E Bequignon, D Isabey, A Coste, ...
PLoS computational biology 13 (7), e1005605, 2017
332017
Deep phenotyping, including quantitative ciliary beating parameters, and extensive genotyping in primary ciliary dyskinesia
S Blanchon, M Legendre, M Bottier, A Tamalet, G Montantin, N Collot, ...
Journal of medical genetics 57 (4), 237-244, 2020
322020
Mutation of CFAP57, a protein required for the asymmetric targeting of a subset of inner dynein arms in Chlamydomonas, causes primary ciliary dyskinesia
XM Bustamante-Marin, A Horani, M Stoyanova, WL Charng, M Bottier, ...
PLoS genetics 16 (8), e1008691, 2020
302020
Endotyping chronic obstructive pulmonary disease, bronchiectasis, and the “chronic obstructive pulmonary disease–bronchiectasis association”
JTJ Huang, E Cant, HR Keir, AK Barton, E Kuzmanova, M Shuttleworth, ...
American Journal of Respiratory and Critical Care Medicine 206 (4), 417-426, 2022
272022
FcRn-dependent transcytosis of monoclonal antibody in human nasal epithelial cells in vitro: a prerequisite for a new delivery route for therapy?
E Bequignon, C Dhommée, C Angely, L Thomas, M Bottier, E Escudier, ...
International journal of molecular sciences 20 (6), 1379, 2019
272019
A new index for characterizing micro-bead motion in a flow induced by ciliary beating: Part II, modeling
M Bottier, M Peña Fernández, G Pelle, D Isabey, B Louis, JB Grotberg, ...
PLoS computational biology 13 (7), e1005552, 2017
202017
Acoustic trap-and-release for rapid assessment of cell motility
M Kim, E Huff, M Bottier, SK Dutcher, PV Bayly, JM Meacham
Soft Matter 15 (21), 4266-4275, 2019
142019
Multiscale evaluation of cellular adhesion alteration and cytoskeleton remodeling by magnetic bead twisting
D Isabey, G Pelle, S André Dias, M Bottier, NM Nguyen, M Filoche, ...
Biomechanics and modeling in mechanobiology 15, 947-963, 2016
142016
TUBB4B variants specifically impact ciliary function, causing a ciliopathic spectrum
S Mechaussier, DO Dodd, PL Yeyati, F McPhie, T Attard, A Shoemark, ...
medRxiv, 2022.10. 19.22280748, 2022
92022
Methods for the assessment of human airway ciliary function
CL Jackson, M Bottier
European Respiratory Journal 60 (1), 2022
82022
Endotyping COPD, bronchiectasis and the “COPD-bronchiectasis association”
JTJ Huang, E Cant, HR Keir, AK Barton, E Kuzmanova, M Shuttleworth, ...
Am J Respir Crit Care Med 206 (4), 417-426, 2022
82022
Characterization of upper airway ciliary beat by coupling isolated and collective cilia motion analysis
M Bottier, S Blanchon, M Filoche, D Isabey, A Coste, E Escudier, ...
Cilia 4, 1-1, 2015
32015
IL-4 levels in sputum correlate with increased mucus production and ciliary dysfunction
E Cant, M Bottier, M Shuttleworth, F Daudvohra, RJ Urquhart, A Gilmour, ...
European Respiratory Journal 60 (suppl 66), 2022
22022
The role of the NLRP3 inflammasome in mucociliary clearance in bronchiectasis: The EMBARC-BRIDGE study
LP Soriano, M Bottier, E Cant, H Richardson, AJ Dicker, M Shuttleworth, ...
European Respiratory Journal 60 (suppl 66), 2022
22022
Mapping inflammatory endotypes of bronchiectasis associated with impaired mucociliary clearance
M Bottier, E Cant, L Delgado, DM Cassidy, YH Giam, A Smith, ...
European Respiratory Journal 58 (suppl 65), 2021
22021
Ciliopathy patient variants reveal organelle-specific functions for TUBB4B in axonemal microtubules
DO Dodd, S Mechaussier, PL Yeyati, F McPhie, JR Anderson, CJ Khoo, ...
Science 384 (6694), eadf5489, 2024
12024
Characterization of ciliary function in bronchiectasis (EMBARC-BRIDGE study)
M Bottier, L Delgado, MK Shuttleworth, DM Cassidy, ML Crichton, ...
A62. Cystic Fibrosis and Non-CF Bronchiectasis: Mechanistic Insights, A2000 …, 2022
12022
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