| Towards a platform PBPK model to characterize the plasma and tissue disposition of monoclonal antibodies in preclinical species and human DK Shah, AM Betts Journal of pharmacokinetics and pharmacodynamics 39, 67-86, 2012 | 378 | 2012 |
| Antibody biodistribution coefficients: inferring tissue concentrations of monoclonal antibodies based on the plasma concentrations in several preclinical species and human DK Shah, AM Betts MAbs 5 (2), 297-305, 2013 | 205 | 2013 |
| Bench to bedside translation of antibody drug conjugates using a multiscale mechanistic PK/PD model: a case study with brentuximab-vedotin DK Shah, N Haddish-Berhane, A Betts Journal of Pharmacokinetics and Pharmacodynamics, 1-17, 2012 | 158 | 2012 |
| Influence of molecular size on tissue distribution of antibody fragments Z Li, BF Krippendorff, S Sharma, AC Walz, T Lavé, DK Shah MAbs 8 (1), 113-119, 2016 | 139 | 2016 |
| Quantitative characterization of in vitro bystander effect of antibody-drug conjugates AP Singh, S Sharma, DK Shah Journal of pharmacokinetics and pharmacodynamics 43, 567-582, 2016 | 110 | 2016 |
| Antibody–drug conjugates: an emerging modality for the treatment of cancer M Leal, P Sapra, SA Hurvitz, P Senter, A Wahl, M Schutten, DK Shah, ... Annals of the New York Academy of Sciences 1321 (1), 41-54, 2014 | 104 | 2014 |
| On translation of antibody drug conjugates efficacy from mouse experimental tumors to the clinic: a PK/PD approach N Haddish-Berhane, DK Shah, D Ma, M Leal, HP Gerber, P Sapra, ... Journal of pharmacokinetics and pharmacodynamics 40, 557-571, 2013 | 75 | 2013 |
| Antibody pharmacokinetics in rat brain determined using microdialysis HY Chang, K Morrow, E Bonacquisti, WY Zhang, DK Shah MAbs 10 (6), 843-853, 2018 | 67 | 2018 |
| Application of Pharmacokinetic-Pharmacodynamic Modeling and Simulation for Antibody-Drug Conjugate Development. A Singh, Y Shin, DK Shah Pharmaceutical Research, 2015 | 58 | 2015 |
| A translational quantitative systems pharmacology model for CD3 bispecific molecules: application to quantify T cell-mediated tumor cell killing by P-cadherin LP DART® A Betts, N Haddish-Berhane, DK Shah, PH van der Graaf, F Barletta, ... The AAPS journal 21, 1-16, 2019 | 57 | 2019 |
| A Priori Prediction of Tumor Payload Concentrations: Preclinical Case Study with an Auristatin-Based Anti-5T4 Antibody-Drug Conjugate DK Shah, LE King, X Han, JA Wentland, Y Zhang, J Lucas, ... The AAPS journal 16, 452-463, 2014 | 55 | 2014 |
| A translational platform PBPK model for antibody disposition in the brain HY Chang, S Wu, G Meno-Tetang, DK Shah Journal of pharmacokinetics and pharmacodynamics 46, 319-338, 2019 | 54 | 2019 |
| Current progress and limitations of AAV mediated delivery of protein therapeutic genes and the importance of developing quantitative pharmacokinetic/pharmacodynamic (PK/PD) models EA Chowdhury, G Meno-Tetang, HY Chang, S Wu, HW Huang, T Jamier, ... Advanced Drug Delivery Reviews 170, 214-237, 2021 | 48 | 2021 |
| Pharmacokinetic and pharmacodynamic considerations for the next generation protein therapeutics DK Shah Journal of pharmacokinetics and pharmacodynamics 42, 553-571, 2015 | 48 | 2015 |
| Influence of molecular size on the clearance of antibody fragments Z Li, BF Krippendorff, DK Shah Pharmaceutical research 34, 2131-2141, 2017 | 47 | 2017 |
| Application of a PK-PD modeling and simulation-based strategy for clinical translation of antibody-drug conjugates: a case study with trastuzumab emtansine (T-DM1) AP Singh, DK Shah The AAPS journal 19, 1054-1070, 2017 | 47 | 2017 |
| Evolution of antibody-drug conjugate tumor disposition model to predict preclinical tumor pharmacokinetics of trastuzumab-emtansine (T-DM1) AP Singh, KF Maass, AM Betts, KD Wittrup, C Kulkarni, LE King, A Khot, ... The AAPS journal 18, 861-875, 2016 | 46 | 2016 |
| Use of an anti-vascular endothelial growth factor antibody in a pharmacokinetic strategy to increase the efficacy of intraperitoneal chemotherapy DK Shah, BS Shin, J Veith, K Tóth, RJ Bernacki, JP Balthasar Journal of Pharmacology and Experimental Therapeutics 329 (2), 580-591, 2009 | 46 | 2009 |
| Pharmacokinetics of protein and peptide conjugates B Bumbaca, Z Li, DK Shah Drug metabolism and pharmacokinetics 34 (1), 42-54, 2019 | 44 | 2019 |
| Alteration of skin hydration and its barrier function by vehicle and permeation enhancers: a study using TGA, FTIR, TEWL and drug permeation as markers DK Shah, S Khandavilli, R Panchagnula Methods Find Exp Clin Pharmacol 30 (7), 499-512, 2008 | 44 | 2008 |
