| ORY-1001, a potent and selective covalent KDM1A inhibitor, for the treatment of acute leukemia T Maes, C Mascaró, I Tirapu, A Estiarte, F Ciceri, S Lunardi, N Guibourt, ... Cancer cell 33 (3), 495-511. e12, 2018 | 268 | 2018 |
| Pancreatic stellate cells radioprotect pancreatic cancer cells through β1-integrin signaling TS Mantoni, S Lunardi, O Al-Assar, A Masamune, TB Brunner Cancer research 71 (10), 3453-3458, 2011 | 247 | 2011 |
| The stromal compartments in pancreatic cancer: are there any therapeutic targets? S Lunardi, RJ Muschel, TB Brunner Cancer letters 343 (2), 147-155, 2014 | 198 | 2014 |
| IP-10/CXCL10 induction in human pancreatic cancer stroma influences lymphocytes recruitment and correlates with poor survival S Lunardi, NB Jamieson, SY Lim, KL Griffiths, M Carvalho-Gaspar, ... Oncotarget 5 (22), 11064, 2014 | 129 | 2014 |
| KDM1 histone lysine demethylases as targets for treatments of oncological and neurodegenerative disease T Maes, C Mascaró, A Ortega, S Lunardi, F Ciceri, TCP Somervaille, ... Epigenomics 7 (4), 609-626, 2015 | 94 | 2015 |
| IP-10/CXCL10 attracts regulatory T cells: Implication for pancreatic cancer S Lunardi, SY Lim, RJ Muschel, TB Brunner Oncoimmunology 4 (9), e1027473, 2015 | 88 | 2015 |
| Contextual regulation of pancreatic cancer stem cell phenotype and radioresistance by pancreatic stellate cells O Al-Assar, F Demiciorglu, S Lunardi, MM Gaspar-Carvalho, ... Radiotherapy and Oncology 111 (2), 243-251, 2014 | 79 | 2014 |
| Breast cancer stem-like cells show dominant homologous recombination due to a larger S-G2 fraction O Al-Assar, T Mantoni, S Lunardi, G Kingham, T Helleday, TB Brunner Cancer biology & therapy 11 (12), 1028-1035, 2011 | 41 | 2011 |
| Predicting In Vivo Efficacy from In Vitro Data: Quantitative Systems Pharmacology Modeling for an Epigenetic Modifier Drug in Cancer M Bouhaddou, LJ Yu, S Lunardi, SK Stamatelos, F Mack, JM Gallo, ... Clinical and Translational Science 13 (2), 419-429, 2020 | 20 | 2020 |
| The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries S Grasso, J Chapelle, V Salemme, S Aramu, I Russo, N Vitale, ... Nature Communications 8 (1), 14797, 2017 | 18 | 2017 |
| Neuroendocrine gene transcript expression is associated with efficacy to lysine-specific demethylase-1 inhibitor RG6016 in small cell lung cancer-derived cell lines F Milletti, WY Cheng, T Maes, S Lunardi, M DeMario, WE Pierceall, ... Cancer Research 76 (14_Supplement), 4708-4708, 2016 | 18 | 2016 |
| Chemoprobe-based assays of histone lysine demethylase 1A target occupation enable in vivo pharmacokinetics and pharmacodynamics studies of KDM1A inhibitors C Mascaró, A Ortega, E Carceller, RR Rodriguez, F Ciceri, S Lunardi, ... Journal of Biological Chemistry 294 (20), 8311-8322, 2019 | 15 | 2019 |
| The radiosensitizing effects of Nelfinavir on pancreatic cancer with and without pancreatic stellate cells O Al-Assar, MI Bittner, S Lunardi, MR Stratford, WG McKenna, TB Brunner Radiotherapy and Oncology 119 (2), 300-305, 2016 | 13 | 2016 |
| Combinations of lsd1 inhibitors for the treatment of hematological malignancies F Ciceri, S Lunardi, T Maes, CM CRUSAT, ITF DE LA CUESTA US Patent App. 15/458,636, 2017 | 6 | 2017 |
| Combinations of LSD1 inhibitors for use in the treatment of solid tumors MD DeMario, T Maes, WE Pierceall, M Fiona, S Lunardi US Patent 10,265,279, 2019 | 5 | 2019 |
| Efficacy of vafidemstat in experimental autoimmune encephalomyelitis highlights the KDM1A/RCOR1/HDAC epigenetic axis in multiple sclerosis F Cavalcanti, E Gonzalez-Rey, M Delgado, CP Falo, L Mestre, C Guaza, ... Pharmaceutics 14 (7), 1420, 2022 | 3 | 2022 |
| The scaffold protein p140Cap limits ERBB2-mediated breast cancer progression interfering with Rac GTPase-controlled circuitries (vol 8, 14797, 2017) S Grasso, J Chapelle, V Salemme, S Aramu, I Russo, N Vitale, ... NATURE COMMUNICATIONS 9, 2018 | 2* | 2018 |
| Efficacy of vafidemstat in experimental autoimmune encephalomyelitis highlights the KDM1A/RCOR1/HDAC epigenetic axis in multiple sclerosis F Cavalcanti, E González-Rey, M Delgado, L Mestre, C Guaza, ... Research Square, 2020 | 1 | 2020 |
| Biomarkers for determining responsiveness to lsd1 inhibitors MIA SÁNCHEZ, S Lunardi, T Maes, CM CRUSAT US Patent App. 16/346,915, 2019 | 1 | 2019 |
| Influence of IP-10/CXCL10 induction in human pancreatic cancer stroma on lymphocytes recruitment and correlation with survival. TB Brunner, S Lunardi, NB Jamieson, SY Lim, KL Griffiths, ... Journal of Clinical Oncology 33 (3_suppl), 290-290, 2015 | 1 | 2015 |
