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Mathieu Bourdenx
Mathieu Bourdenx
UK Dementia Research Institute at University College London
Adresse e-mail validée de ucl.ac.uk - Page d'accueil
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Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson's disease
MF Bastide, WG Meissner, B Picconi, S Fasano, PO Fernagut, M Feyder, ...
Progress in neurobiology 132, 96-168, 2015
4852015
Selective autophagy as a potential therapeutic target for neurodegenerative disorders
A Scrivo, M Bourdenx, O Pampliega, AM Cuervo
The Lancet Neurology 17 (9), 802-815, 2018
3022018
Chaperone-mediated autophagy prevents collapse of the neuronal metastable proteome
M Bourdenx, A Martín-Segura, A Scrivo, JA Rodriguez-Navarro, ...
Cell 184 (10), 2696-2714. e25, 2021
1812021
Nanoparticles restore lysosomal acidification defects: Implications for Parkinson and other lysosomal-related diseases
M Bourdenx, J Daniel, E Genin, FN Soria, M Blanchard-Desce, E Bezard, ...
Autophagy 12 (3), 472-483, 2016
1802016
Protein aggregation and neurodegeneration in prototypical neurodegenerative diseases: Examples of amyloidopathies, tauopathies and synucleinopathies
M Bourdenx, NS Koulakiotis, D Sanoudou, E Bezard, B Dehay, ...
Progress in neurobiology 155, 171-193, 2017
1722017
The different autophagy degradation pathways and neurodegeneration
A Fleming, M Bourdenx, M Fujimaki, C Karabiyik, GJ Krause, A Lopez, ...
Neuron, 2022
1702022
Proteome-wide analysis of chaperone-mediated autophagy targeting motifs
P Kirchner, M Bourdenx, J Madrigal-Matute, S Tiano, A Diaz, BA Bartholdy, ...
PLoS biology 17 (5), e3000301, 2019
1662019
Bidirectional gut-to-brain and brain-to-gut propagation of synucleinopathy in non-human primates
ML Arotcarena, S Dovero, A Prigent, M Bourdenx, S Camus, G Porras, ...
Brain 143 (5), 1462-1475, 2020
1622020
Exosomes, an unmasked culprit in neurodegenerative diseases
FN Soria, O Pampliega, M Bourdenx, WG Meissner, E Bezard, B Dehay
Frontiers in neuroscience 11, 26, 2017
1402017
Lack of additive role of ageing in nigrostriatal neurodegeneration triggered by α-synuclein overexpression
M Bourdenx, S Dovero, M Engeln, S Bido, MF Bastide, N Dutheil, ...
Acta neuropathologica communications 3 (1), 1-15, 2015
1202015
Acetylated tau inhibits chaperone-mediated autophagy and promotes tau pathology propagation in mice
B Caballero, M Bourdenx, E Luengo, A Diaz, PD Sohn, X Chen, C Wang, ...
Nature Communications 12 (1), 1-18, 2021
1182021
In vitro α-synuclein neurotoxicity and spreading among neurons and astrocytes using Lewy body extracts from Parkinson disease brains
F Cavaliere, L Cerf, B Dehay, P Ramos-Gonzalez, F De Giorgi, ...
Neurobiology of disease 103, 101-112, 2017
1152017
Lysosomes and α-synuclein form a dangerous duet leading to neuronal cell death
M Bourdenx, E Bezard, B Dehay
Frontiers in neuroanatomy 8, 83, 2014
992014
Systemic gene delivery to the central nervous system using Adeno-associated virus
M Bourdenx, N Dutheil, E Bezard, B Dehay
Frontiers in molecular neuroscience 7, 50, 2014
992014
Selective inactivation of striatal FosB/ΔFosB-expressing neurons alleviates L-DOPA–induced dyskinesia
M Engeln, MF Bastide, E Toulmé, B Dehay, M Bourdenx, E Doudnikoff, ...
Biological psychiatry 79 (5), 354-361, 2016
872016
Transcription factor EB overexpression prevents neurodegeneration in experimental synucleinopathies
ML Arotcarena, M Bourdenx, N Dutheil, ML Thiolat, E Doudnikoff, ...
JCI insight 4 (16), 2019
582019
Targeting α‐synuclein: Therapeutic options
B Dehay, M Decressac, M Bourdenx, I Guadagnino, PO Fernagut, ...
Movement Disorders 31 (6), 882-888, 2016
492016
Reciprocal regulation of chaperone-mediated autophagy and the circadian clock
YR Juste, S Kaushik, M Bourdenx, R Aflakpui, S Bandyopadhyay, ...
Nature Cell Biology 23 (12), 1255-1270, 2021
382021
Identification of distinct pathological signatures induced by patient-derived α-synuclein structures in nonhuman primates
M Bourdenx, A Nioche, S Dovero, ML Arotcarena, S Camus, G Porras, ...
Science advances 6 (20), eaaz9165, 2020
382020
Protective role of chaperone-mediated autophagy against atherosclerosis
J Madrigal-Matute, J de Bruijn, K van Kuijk, DF Riascos-Bernal, A Diaz, ...
Proceedings of the National Academy of Sciences 119 (14), e2121133119, 2022
332022
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