Ribosome• RelA structures reveal the mechanism of stringent response activation AB Loveland, E Bah, R Madireddy, Y Zhang, AF Brilot, N Grigorieff, ... Elife 5, e17029, 2016 | 164 | 2016 |
Bisubstrate inhibitors of the MYST HATs Esa1 and Tip60 J Wu, N Xie, Z Wu, Y Zhang, YG Zheng Bioorganic & medicinal chemistry 17 (3), 1381-1386, 2009 | 77 | 2009 |
Structures of darunavir-resistant HIV-1 protease mutant reveal atypical binding of darunavir to wide open flaps Y Zhang, YCE Chang, JM Louis, YF Wang, RW Harrison, IT Weber ACS chemical biology 9 (6), 1351-1358, 2014 | 37 | 2014 |
The L76V drug resistance mutation decreases the dimer stability and rate of autoprocessing of HIV-1 protease by reducing internal hydrophobic contacts JM Louis, Y Zhang, JM Sayer, YF Wang, RW Harrison, IT Weber Biochemistry 50 (21), 4786-4795, 2011 | 36 | 2011 |
Potent antiviral HIV-1 protease inhibitor GRL-02031 adapts to the structures of drug resistant mutants with its P1′-pyrrolidinone ring YCE Chang, XX Yu, Y Zhang, Y Tie, YF Wang, S Yashchuk, AK Ghosh, ... Journal of medicinal chemistry 55 (7), 3387-3397, 2012 | 25 | 2012 |
Structural basis for a hand-like site in the calcium sensor CatchER with fast kinetics Y Zhang, F Reddish, S Tang, Y Zhuo, YF Wang, JJ Yang, IT Weber Acta Crystallographica Section D: Biological Crystallography 69 (12), 2309-2319, 2013 | 13 | 2013 |
HIV-1 Protease and AIDS therapy IT Weber, Y Zhang, J Tözsér Viral Proteases and Antiviral Protease Inhibitor Therapy: Proteases in …, 2009 | 12 | 2009 |
Structural insights into ribosome structure and translation regulation A Korostelev, E Bah, CS Koh, R Madireddy, E Svidritskiy, Y Zhang The FASEB Journal 29, 711.23, 2015 | | 2015 |
HIV-1 protease drug resistance mutant L76V exhibits decreased dimer stability and lower rate of autoprocessing via reduced internal hydrophobic contacts Y Zhang, JM Louis, JM Sayer, YF Wang, RW Harrison, IT Weber ABSTRACTS OF PAPERS OF THE AMERICAN CHEMICAL SOCIETY 243, 2012 | | 2012 |
HIV-1 PR P51 Mutant Complex Formation with Inhibitors ST Greene, Y Zhang | | 2012 |