| Structure of parkin reveals mechanisms for ubiquitin ligase activation JF Trempe, V Sauvé, K Grenier, M Seirafi, MY Tang, M Ménade, ... Science 340 (6139), 1451-1455, 2013 | 541 | 2013 |
| USP 8 regulates mitophagy by removing K 6‐linked ubiquitin conjugates from parkin TM Durcan, MY Tang, JR Pérusse, EA Dashti, MA Aguileta, GL McLelland, ... The EMBO journal 33 (21), 2473-2491, 2014 | 376 | 2014 |
| Defending the mitochondria: The pathways of mitophagy and mitochondrial-derived vesicles RF Roberts, MY Tang, EA Fon, TM Durcan The international journal of biochemistry & cell biology 79, 427-436, 2016 | 113 | 2016 |
| Structure-guided mutagenesis reveals a hierarchical mechanism of Parkin activation MY Tang, M Vranas, AI Krahn, S Pundlik, JF Trempe, EA Fon Nature communications 8 (1), 14697, 2017 | 85 | 2017 |
| The landscape of Parkin variants reveals pathogenic mechanisms and therapeutic targets in Parkinson’s disease W Yi, EJ MacDougall, MY Tang, AI Krahn, Z Gan-Or, JF Trempe, EA Fon Human molecular genetics 28 (17), 2811-2825, 2019 | 69 | 2019 |
| Viral delivery of CAR targets to solid tumors enables effective cell therapy A Aalipour, F Le Boeuf, M Tang, S Murty, F Simonetta, AX Lozano, ... Molecular Therapy-Oncolytics 17, 232-240, 2020 | 46 | 2020 |
| Loss of UCHL1 promotes age-related degenerative changes in the enteric nervous system J Coulombe, P Gamage, MT Gray, M Zhang, MY Tang, J Woulfe, ... Frontiers in aging neuroscience 6, 129, 2014 | 36 | 2014 |
| Bcl-2-associated athanogene 5 (BAG5) regulates Parkin-dependent mitophagy and cell death ML De Snoo, EL Friesen, YT Zhang, R Earnshaw, G Dorval, M Kapadia, ... Cell Death & Disease 10 (12), 907, 2019 | 33 | 2019 |
| Experimental and Computational Analysis of Polyglutamine-Mediated Cytotoxicity M Tang University of Ottawa, 2012 | 17 | 2012 |
| Experimental and computational analysis of polyglutamine-mediated cytotoxicity MY Tang, CJ Proctor, J Woulfe, DA Gray PLoS computational biology 6 (9), e1000944, 2010 | 17 | 2010 |
| Delayed spinocerebellar ataxia in transgenic mice expressing mutant ubiquitin M Tsirigotis, MY Tang, M Beyers, M Zhang, J Woulfe, DA Gray Neuropathology and applied neurobiology 32 (1), 26-39, 2006 | 17 | 2006 |
| Activation of p38MAPK contributes to expanded polyglutamine-induced cytotoxicity M Tsirigotis, RM Baldwin, MY Tang, IAJ Lorimer, DA Gray PloS one 3 (5), e2130, 2008 | 14 | 2008 |
| Protective effects of mutant ubiquitin in transgenic mice DA Gray, M Tsirigotis, J Brun, M Tang, M Zhang, M Beyers, J Woulfe Annals of the New York Academy of Sciences 1019 (1), 215-218, 2004 | 12 | 2004 |
| CRISPR-mediated rapid arming of poxvirus vectors enables facile generation of the novel immunotherapeutic STINGPOX JT Whelan, R Singaravelu, F Wang, A Pelin, LA Tamming, G Pugliese, ... Frontiers in Immunology 13, 1050250, 2023 | 3 | 2023 |
| Abstract PR19: utilizing novel oncolytic vaccinia virus for selective expression of immunotherapeutic payloads in metastatic tumors A Pelin, M Huh, M Tang, F LeBouef, B Keller, J Duong, K Knowles, ... Cancer Immunology Research 8 (4_Supplement), PR19-PR19, 2020 | 2 | 2020 |
| Modified vaccinia vectors JC Bell, F Le Boeuf, BA KELLER, A PELIN US Patent App. 17/694,115, 2023 | 1 | 2023 |
| Modified orthopoxvirus vectors JC Bell, A PELIN, CJ BREITBACH, MF BURGESS, SH BERNSTEIN US Patent App. 17/415,606, 2022 | 1 | 2022 |
| Abstract B101: Novel oncolytic vaccinia virus platform for systemic delivery of immunotherapeutic payloads JC Bell, A Pelin, M Huh, M Tang, FL Boeuf, B Keller, J Duong, ... Cancer Immunology Research 7 (2_Supplement), B101-B101, 2019 | 1 | 2019 |
| Dysfunction of the Ubiquitin/Proteasome System and Mitochondria in Neurodegenerative Disease MY Tang, DA Gray Mitochondrial Dysfunction in Neurodegenerative Disorders, 141-155, 2012 | 1 | 2012 |
| Structure and dynamics of pathway activation by the Toll immunoreceptor from the viral mosquito vector Aedes aegypti M Gangloff, Y Saucereau, T Wilson, M Tang, M Moncrieffe, S Hardwick, ... | | 2021 |
Edward A. FonMontreal Neurological Institute, McGill UniversityAdresse e-mail validée de mcgill.ca
